(Q36098879)

12 August 2017

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title

HIV-1 infection and AIDS: consequences for the central nervous system (English)

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12 August 2017

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Kaul M

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12 August 2017

Zheng J

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12 August 2017

Okamoto S

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12 August 2017

Gendelman HE

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12 August 2017

Lipton SA

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12 August 2017

language of work or name

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1 August 2005

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Cell Death & Differentiation

12 August 2017

published in

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12 August 2017

volume

12 Suppl 1

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12 August 2017

page(s)

878-892

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The global impact of HIV/AIDS

12 August 2017

cites work

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Chemokines in the CNS: plurifunctional mediators in diverse states

21 January 2018

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HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels

21 January 2018

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Microglia-passaged simian immunodeficiency virus induces neurophysiological abnormalities in monkeys

21 January 2018

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Chemokines and chemokine receptors in the CNS: a possible role in neuroinflammation and patterning

21 January 2018

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IL-16 expression in lymphocytes and microglia in HIV-1 encephalitis

21 January 2018

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Induction of matrix metalloproteinase-2 in human immunodeficiency virus-1 glycoprotein 120 transgenic mouse brains.

21 January 2018

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A new class of membrane-bound chemokine with a CX3C motif

21 January 2018

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Neuropathology of Human Immunodeficiency Virus Infection

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Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia

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21 January 2018

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Cellular localization of tumor necrosis factor mRNA in neurological tissue from HIV-infected patients by combined reverse transcriptase/polymerase chain reaction in situ hybridization and immunohistochemistry

21 January 2018

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Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status

21 January 2018

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Glutamate is a mediator of neurotoxicity in secretions of activated HIV-1-infected macrophages

21 January 2018

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Neuronal apoptosis in HIV infection in adults

21 January 2018

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Apoptotic neurons in brains from paediatric patients with HIV-1 encephalitis and progressive encephalopathy.

21 January 2018

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Neuronal apoptosis does not correlate with dementia in HIV infection but is related to microglial activation and axonal damage

21 January 2018

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The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes

21 January 2018

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Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity.

21 January 2018

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Cytokine-stimulated, but not HIV-infected, human monocyte-derived macrophages produce neurotoxic levels of l -cysteine

21 January 2018

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Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

21 January 2018

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Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity

21 January 2018

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Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

21 January 2018

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Chemokine receptors: signposts to brain development and disease

21 January 2018

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Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

21 January 2018

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The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

21 January 2018

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Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

21 January 2018

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Chemokines and chemokine receptors: biology and clinical relevance in inflammation and AIDS.

21 January 2018

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Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells

21 January 2018

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CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1

21 January 2018

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The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

21 January 2018

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CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

21 January 2018

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Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis.

21 January 2018

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Development of a human neuronal cell model for human immunodeficiency virus (HIV)-infected macrophage-induced neurotoxicity: apoptosis induced by HIV type 1 primary isolates and evidence for involvement of the Bcl-2/Bcl-xL-sensitive intrinsic apopto

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4.

21 January 2018

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Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis

21 January 2018

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Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia

21 January 2018

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CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity

21 January 2018

1 reference

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Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Cloning and characterization of SDF-1gamma, a novel SDF-1 chemokine transcript with developmentally regulated expression in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Expression of stromal cell-derived factor 1alpha protein in HIV encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration

21 January 2018

1 reference

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Lentivirus infection in the brain induces matrix metalloproteinase expression: role of envelope diversity

21 January 2018

1 reference

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Haptoglobin polymorphism, iron metabolism and mortality in HIV infection

21 January 2018

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Chemokine and chemokine-receptor expression in human glial elements: induction by the HIV protein, Tat, and chemokine autoregulation

21 January 2018

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Stromal cell-derived factor 1-mediated CXCR4 signaling in rat and human cortical neural progenitor cells

21 January 2018

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Regenerating the damaged central nervous system

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Functional neurogenesis in the adult hippocampus

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Neurogenesis after ischaemic brain insults

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Embryonic expression of the mRNA for the rat homologue of the fusin/CXCR-4 HIV-1 co-receptor

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor

21 January 2018

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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

21 January 2018

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Chemokines promote quiescence and survival of human neural progenitor cells

21 January 2018

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HIV-1 promotes quiescence in human neural progenitor cells

21 January 2018

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HIV-1 infected immune competent mononuclear phagocytes influence the pathways to neuronal demise

21 January 2018

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CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons

21 January 2018

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Expression of CX3CR1 chemokine receptors on neurons and their role in neuronal survival

21 January 2018

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Gp120 can revert antagonism at the glycine site of NMDA receptors mediating GABA release from cultured hippocampal neurons

21 January 2018

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Extracellular HIV-1 virus protein R causes a large inward current and cell death in cultured hippocampal neurons: implications for AIDS pathology

21 January 2018

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Apoptosis induced by HIV-1 infection of the central nervous system

21 January 2018

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Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide.

21 January 2018

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Neuronal injury due to HIV-1 envelope protein is blocked by anti-gp120 antibodies but not by anti-CD4 antibodies

21 January 2018

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HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists

21 January 2018

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Human immunodeficiency virus-infected macrophages produce soluble factors that cause histological and neurochemical alterations in cultured human brains

21 January 2018

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Prospects for clinically tolerated NMDA antagonists: open-channel blockers and alternative redox states of nitric oxide

21 January 2018

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An experimental model system for HIV-1-induced brain injury

21 January 2018

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Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine

21 January 2018

1 reference

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Mitochondrial and extramitochondrial apoptotic signaling pathways in cerebrocortical neurons

21 January 2018

1 reference

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p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein

21 January 2018

1 reference

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Requirement for nitric oxide activation of p21(ras)/extracellular regulated kinase in neuronal ischemic preconditioning

21 January 2018

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Suppression of neuronal apoptosis by S-nitrosylation of caspases

21 January 2018

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Perturbation of sphingolipid metabolism and ceramide production in HIV-dementia

21 January 2018

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S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death

21 January 2018

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Differential modulation of cell death proteins in human brain cells by tumor necrosis factor alpha and platelet activating factor

21 January 2018

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Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA

21 January 2018

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21 January 2018

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Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice.

21 January 2018

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21 January 2018

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Memantine protects hippocampal neuronal function in murine human immunodeficiency virus type 1 encephalitis.

21 January 2018

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Differential immunochemical markers reveal the normal distribution of brain macrophages and microglia in the developing rat brain

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Macrophage proteomic fingerprinting predicts HIV-1-associated cognitive impairment.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Microglia-derived IGF-2 prevents TNFalpha induced death of mature oligodendrocytes in vitro

21 January 2018

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Nerve growth factor is an autocrine factor essential for the survival of macrophages infected with HIV

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Specificity of neurotrophin-3 determined by loss-of-function mutagenesis

21 January 2018

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HIV-1 infection of subcortical astrocytes in the pediatric central nervous system

21 January 2018

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Pathobiology of human immunodeficiency virus dementia

21 January 2018

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Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Kynurenine pathway inhibition reduces neurotoxicity of HIV-1-infected macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

CNS invasion by CD14+/CD16+ peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Tumor necrosis factor-related apoptosis-inducing ligand induces neuronal death in a murine model of HIV central nervous system infection

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Identification and characterization of a new member of the TNF family that induces apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

The receptor for the cytotoxic ligand TRAIL

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

BH3-Only proteins-essential initiators of apoptotic cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

A unified model for apical caspase activation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Death receptors: signaling and modulation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Cell death inhibition: keeping caspases in check

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Memantine prevents HIV coat protein-induced neuronal injury in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Randomized trial of the platelet-activating factor antagonist lexipafant in HIV-associated cognitive impairment. Neurological AIDS Research Consortium.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

A phase I/II trial of nimodipine for HIV-related neurologic complications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Transdermal selegiline in HIV-associated cognitive impairment: pilot, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Immunohistochemical localization of protein kinase C delta during postnatal development of the cerebellum

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Signalling pathways in the brain: cellular transduction of mood stabilisation in the treatment of manic-depressive illness

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Insulin and Insulin-like Growth Factor-1 Regulate Tau Phosphorylation in Cultured Human Neurons

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Lithium ameliorates HIV-gp120-mediated neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Erythropoietin protects cerebrocortical neurons from HIV-1/gp120-induced damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Erythropoietin for neurologic protection and diabetic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

The Molecular Basis of the Chemokine/Chemokine Receptor Interaction—Scope for Design of Chemokine Antagonists

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

Cerebrospinal fluid beta chemokine concentrations in neurocognitively impaired individuals infected with human immunodeficiency virus type 1.

21 January 2018

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Apoptosis in the nervous system

21 January 2018

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Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)

21 January 2018

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Neurologic manifestations of AIDS.

21 January 2018

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7 January 2021

Progress in clinical neurosciences: The neuropathogenesis of HIV infection: host-virus interaction and the impact of therapy.

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7 January 2021

Neurocognitive impairment is an independent risk factor for death in HIV infection. San Diego HIV Neurobehavioral Research Center Group

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7 January 2021

HIV infection and dementia

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7 January 2021

Trends in incidence of AIDS illnesses in Australia from 1983 to 1994: the Australian AIDS cohort

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7 January 2021

Changes to AIDS dementia complex in the era of highly active antiretroviral therapy

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7 January 2021

HIV-associated dementia

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7 January 2021

Human immunodeficiency virus-associated dementia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

TNF-α Opens a Paracellular Route for HIV-1 Invasion across the Blood-Brain Barrier

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Neuronal death induced by brain-derived human immunodeficiency virus type 1 envelope genes differs between demented and nondemented AIDS patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Study of receptor-mediated neurotoxins released by HIV-1-infected mononuclear phagocytes found in human brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Cortical synaptic density is reduced in mild to moderate human immunodeficiency virus neurocognitive disorder. HNRC Group. HIV Neurobehavioral Research Center.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Selective neuronal vulnerability in HIV encephalitis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Mitochondrial glutaminase enhances extracellular glutamate production in HIV-1-infected macrophages: linkage to HIV-1 associated dementia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

HIV-1 entry inhibitors: evading the issue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Apoptosis induced by infection of primary brain cultures with diverse human immunodeficiency virus type 1 isolates: evidence for a role of the envelope.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

In vivo distribution of the human immunodeficiency virus/simian immunodeficiency virus coreceptors: CXCR4, CCR3, and CCR5.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

HIV associated neurodegeneration requires p53 in neurons and microglia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

A dual role for the SDF-1/CXCR4 chemokine receptor system in adult brain: isoform-selective regulation of SDF-1 expression modulates CXCR4-dependent neuronal plasticity and cerebral leukocyte recruitment after focal ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

CXCR4 regulates interneuron migration in the developing neocortex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Caspase cascades in human immunodeficiency virus-associated neurodegeneration.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

An analysis of HIV-1-associated inflammatory products in brain tissue of humans and SCID mice with HIV-1 encephalitis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Neuronal apoptosis induced by HIV-1 Tat protein and TNF-alpha: potentiation of neurotoxicity mediated by oxidative stress and implications for HIV-1 dementia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Transplantation of activated macrophages overcomes central nervous system regrowth failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Regulated Expression of Sodium‐dependent Glutamate Transporters and Synthetase: a Neuroprotective Role for Activated Microglia and Macrophages in HIV Infection?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Tumor necrosis factor-alpha production by human fetal microglial cells: regulation by other cytokines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Neurotoxic effects of tumor necrosis factor alpha in primary human neuronal cultures are mediated by activation of the glutamate AMPA receptor subtype: implications for AIDS neuropathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

The suicide in the thymus, a twisted trail

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Pharmacotherapy of HIV dementia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Central Neurologic Complications of HIV Infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Neuroprotective activity of chemokines against N-methyl-D-aspartate or beta-amyloid-induced toxicity in culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Role of p38 mitogen-activated protein kinase in axotomy-induced apoptosis of rat retinal ganglion cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401623

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401623

1 reference

Dimensions Publication ID

12 August 2017

1051717697

0 references

1 reference