(Q35911464)

11 August 2017

1 reference

title

Systems biology in drug discovery. (English)

1 reference

11 August 2017

1 reference

1 reference

Ellen L Berg

1 reference

11 August 2017

Eugene C Butcher

1 reference

11 August 2017

Eric J Kunkel

series ordinal

1 reference

11 August 2017

publication date

1 October 2004

1 reference

11 August 2017

1 reference

inferred from page(s)

published in

Nature Biotechnology

1 reference

11 August 2017

1 reference

11 August 2017

1 reference

11 August 2017

page(s)

1253-1259

1 reference

The price of innovation: new estimates of drug development costs

11 August 2017

cites work

1 reference

7 January 2021

A new approach to decoding life: systems biology

1 reference

7 January 2021

Building with a scaffold: emerging strategies for high- to low-level cellular modeling

1 reference

7 January 2021

Integration from proteins to organs: the Physiome Project

1 reference

7 January 2021

Systems biology, proteomics, and the future of health care: toward predictive, preventative, and personalized medicine

1 reference

7 January 2021

Integrative biological analysis of the APOE*3-leiden transgenic mouse

1 reference

7 January 2021

Biomarker discovery by comprehensive phenotyping for autoimmune diseases

1 reference

7 January 2021

A genomic regulatory network for development

1 reference

7 January 2021

Integrated genomic and proteomic analyses of a systematically perturbed metabolic network

1 reference

7 January 2021

Integrating high-throughput and computational data elucidates bacterial networks

1 reference

7 January 2021

Functional discovery via a compendium of expression profiles

1 reference

7 January 2021

Computational physiology and the Physiome Project

1 reference

7 January 2021

Modeling the heart--from genes to cells to the whole organ

1 reference

7 January 2021

The computational integrated myocyte: a view into the virtual heart

1 reference

7 January 2021

Small- and large-scale biosimulation applied to drug discovery and development

1 reference

7 January 2021

Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.

1 reference

7 January 2021

Modeling approaches to type 2 diabetes

1 reference

7 January 2021

Emergent properties of networks of biological signaling pathways

1 reference

7 January 2021

PathBLAST: a tool for alignment of protein interaction networks

1 reference

7 January 2021

Use of human tissue in ADME and safety profiling of development candidates

1 reference

7 January 2021

Genome-scale functional profiling of the mammalian AP-1 signaling pathway

1 reference

7 January 2021

Multidimensional chemical genetic analysis of diversity-oriented synthesis-derived deacetylase inhibitors using cell-based assays

1 reference

7 January 2021

Systematic discovery of multicomponent therapeutics

1 reference

7 January 2021

Drug target validation and identification of secondary drug target effects using DNA microarrays

1 reference

7 January 2021

An integrative biology approach for analysis of drug action in models of human vascular inflammation

1 reference

7 January 2021

Rapid structure-activity and selectivity analysis of kinase inhibitors by BioMAP analysis in complex human primary cell-based models

1 reference

7 January 2021

Method for analyzing signaling networks in complex cellular systems

1 reference

7 January 2021

Statins as novel immunomodulators: From cell to potential clinical benefit

1 reference

7 January 2021

Data-driven computer simulation of human cancer cell

1 reference

7 January 2021

Computational modeling of the EGF-receptor system: a paradigm for systems biology

1 reference

7 January 2021

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

1 reference

7 January 2021

Investigations into the analysis and modeling of the TNF alpha-mediated NF-kappa B-signaling pathway

1 reference

7 January 2021

The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

1 reference

7 January 2021

Identifiers

DOI

10.1038/NBT1017

1 reference

Dimensions Publication ID

11 August 2017

1015044270

0 references

1 reference