(Q35723141)

9 August 2017

title

Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation (English)

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9 August 2017

David A Brenner

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Tian Lan

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9 August 2017

Tatiana Kisseleva

series ordinal

1 reference

9 August 2017

language of work or name

English

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publication date

29 July 2015

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9 August 2017

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9 August 2017

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9 August 2017

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9 August 2017

page(s)

e0129743

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Creative Commons Attribution 4.0 International

9 August 2017

start time

29 July 2015

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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Inhibitory effect of tanshinone IIA on rat hepatic stellate cells

12 July 2018

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Novel role of nuclear receptor Rev-erbα in hepatic stellate cell activation: potential therapeutic target for liver injury

12 July 2018

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12 July 2018

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Thymoquinone attenuates liver fibrosis via PI3K and TLR4 signaling pathways in activated hepatic stellate cells

12 July 2018

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NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development.

12 July 2018

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12 July 2018

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Hedgehog controls hepatic stellate cell fate by regulating metabolism

12 July 2018

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Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent

12 July 2018

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Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo.

12 July 2018

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12 July 2018

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The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice

12 July 2018

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Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism

12 July 2018

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12 July 2018

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α-Lipoic acid inhibits liver fibrosis through the attenuation of ROS-triggered signaling in hepatic stellate cells activated by PDGF and TGF-β.

12 July 2018

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Control of hepatic nuclear superoxide production by glucose 6-phosphate dehydrogenase and NADPH oxidase-4

12 July 2018

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First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis

12 July 2018

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Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway.

12 July 2018

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Toll-like receptor signaling and liver fibrosis

12 July 2018

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Hepatocyte NAD(P)H oxidases as an endogenous source of reactive oxygen species during hepatitis C virus infection

12 July 2018

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Signals from dying hepatocytes trigger growth of liver progenitors

12 July 2018

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Linking oxidative stress to inflammation: Toll-like receptors

12 July 2018

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Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis

12 July 2018

1 reference

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NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury.

12 July 2018

1 reference

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Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4519306

Mechanisms of hepatic fibrogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4519306

Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4519306

TLR4 enhances TGF-beta signaling and hepatic fibrosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4519306

Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4519306

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4519306

Cytochrome P450 2E1-derived reactive oxygen species mediate paracrine stimulation of collagen I protein synthesis by hepatic stellate cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4519306

Oxidative stress-related molecules and liver fibrosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4519306

Silencing of TGF-beta signalling by the pseudoreceptor BAMBI.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4519306

Pathobiology of hepatic stellate cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4519306

The antihepatic fibrotic effects of fluorofenidone via MAPK signalling pathways.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4519306

Hepatic expression of candidate genes in patients with alcoholic hepatitis: correlation with disease severity.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4519306

Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4519306

Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells

25 September 2018

1 reference

12 December 2020

Glutathione Levels Discriminate between Oxidative Stress and Transforming Growth Factor-β Signaling in Activated Rat Hepatic Stellate Cells

1 reference

12 December 2020

Design, synthesis and biological activity of original pyrazolo-pyrido-diazepine, -pyrazine and -oxazine dione derivatives as novel dual Nox4/Nox1 inhibitors

1 reference

12 December 2020

NOX1/nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) oxidase promotes proliferation of stellate cells and aggravates liver fibrosis induced by bile duct ligation

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0129743

Identifiers

DOI

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9 August 2017

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9 August 2017

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