(Q35760937)

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Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells

scientific article published on 15 November 2011

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Europe PubMed Central

PubMed publication ID

10 August 2017

Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells (English)

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Europe PubMed Central

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10 August 2017

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Federica Sotgia

10

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Federica Sotgia

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Europe PubMed Central

PubMed publication ID

10 August 2017

Michael P. Lisanti

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Michael P Lisanti

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10 August 2017

Richard Pestell

8

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Richard G Pestell

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10 August 2017

6

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Chenguang Wang

1 reference

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10 August 2017

Ubaldo E Martinez-Outschoorn

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Ubaldo E Martinez-Outschoorn

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Europe PubMed Central

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10 August 2017

Neal Flomenberg

5

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Neal Flomenberg

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10 August 2017

Stephanos Pavlides

7

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Stephanos Pavlides

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10 August 2017

Allison Goldberg

2

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Allison Goldberg

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10 August 2017

9

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Anthony Howell

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10 August 2017

author name string

Zhao Lin

3

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10 August 2017

Ying-Hui Ko

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10 August 2017

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15 November 2011

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10 August 2017

Cancer Biology and Therapy

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Europe PubMed Central

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10 August 2017

12

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Europe PubMed Central

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10 August 2017

10

1 reference

Europe PubMed Central

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10 August 2017

924-938

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts

1 reference

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2 October 2017

Arsenic-induced oxidative stress and its reversibility.

1 reference

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1 reference

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Identification of PUMA as an estrogen target gene that mediates the apoptotic response to tamoxifen in human breast cancer cells and predicts patient outcome and tamoxifen responsiveness in breast cancer.

1 reference

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A gene expression signature from human breast cancer cells with acquired hormone independence identifies MYC as a mediator of antiestrogen resistance

1 reference

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2 October 2017

Autophagy and Metabolism

1 reference

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HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis

1 reference

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1 reference

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1 reference

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1 reference

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Diabetes and cancer: a consensus report.

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Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors

1 reference

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2 October 2017

Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer

1 reference

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1 reference

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2 October 2017

Long-term metformin use is associated with decreased risk of breast cancer.

1 reference

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2 October 2017

BCL2 and CASP8 regulation by NF-kappaB differentially affect mitochondrial function and cell fate in antiestrogen-sensitive and -resistant breast cancer cells.

1 reference

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2 October 2017

Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model

1 reference

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2 October 2017

Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase

1 reference

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2 October 2017

Modulation of intracellular ROS levels by TIGAR controls autophagy

1 reference

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2 October 2017

Biological determinants of endocrine resistance in breast cancer

1 reference

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2 October 2017

CYP2D6 and tamoxifen: DNA matters in breast cancer

1 reference

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2 October 2017

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

1 reference

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2 October 2017

New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes

1 reference

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2 October 2017

Expression of ER-{alpha}36, a novel variant of estrogen receptor {alpha}, and resistance to tamoxifen treatment in breast cancer

1 reference

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Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer

1 reference

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Topoisomerase II{alpha} amplification does not predict benefit from dose-intense cyclophosphamide, doxorubicin, and fluorouracil therapy in HER2-amplified early breast cancer: results of CALGB 8541/150013

1 reference

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2 October 2017

The substrate domain of BCAR1 is essential for anti-estrogen-resistant proliferation of human breast cancer cells

1 reference

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2 October 2017

Stromal cell expression of caveolin-1 predicts outcome in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280908

2 October 2017

An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers

1 reference

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2 October 2017

Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts

1 reference

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Pharmacogenetics of tamoxifen: who should undergo CYP2D6 genetic testing?

1 reference

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Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation

1 reference

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1 reference

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Estrogen-related cancer microenvironment of breast carcinoma

1 reference

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Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function

1 reference

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1 reference

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1 reference

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1 reference

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Direct involvement of breast tumor fibroblasts in the modulation of tamoxifen sensitivity

1 reference

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Enhanced NF kappa B and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer

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2 October 2017

Cyclin D1 overexpression is a negative predictive factor for tamoxifen response in postmenopausal breast cancer patients

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2 October 2017

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2 October 2017

Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer

1 reference

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2 October 2017

Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells

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Mechanisms of action of arsenic trioxide.

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2 October 2017

Recent trends in breast cancer incidence and mortality

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2 October 2017

Epidemiology of breast cancer.

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2 October 2017

Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression)

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2 October 2017

c-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry

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2 October 2017

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2 October 2017

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12 July 2018

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12 July 2018

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12 July 2018

Prognostic significance of tumor/stromal caveolin‐1 expression in breast cancer patients

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25 September 2018

Metformin and incident breast cancer among diabetic women: a population-based case-control study in Denmark

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25 September 2018

Metformin Suppresses Colorectal Aberrant Crypt Foci in a Short-term Clinical Trial

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25 September 2018

Insulin, glucose and the increased risk of cancer in patients with type 2 diabetes

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25 September 2018

Towards a new "stromal-based" classification system for human breast cancer prognosis and therapy

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25 September 2018

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25 September 2018

Ketone bodies stimulate chaperone-mediated autophagy

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25 September 2018

Molecular changes in tamoxifen-resistant breast cancer: relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase

1 reference

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25 September 2018

Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: a multinational, double-blind, randomized trial

1 reference

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25 September 2018

Nonendocrine pathways and endocrine resistance: observations with antiestrogens and signal transduction inhibitors in combination

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25 September 2018

p27(Kip1) induces quiescence and growth factor insensitivity in tamoxifen-treated breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280908

25 September 2018

Incidence of invasive breast cancer by hormone receptor status from 1992 to 1998.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280908

25 September 2018

Ectopic expression of cyclin E in estrogen responsive cells abrogates antiestrogen mediated growth arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280908

25 September 2018

The impact of caveolin protein expression in tumor stroma on prognosis of breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22041887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/22041887

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/CBT.12.10.17780

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

ResearchGate publication ID

0 references

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