(Q35751042)

10 August 2017

title

Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML. (English)

1 reference

10 August 2017

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Marina Konopleva

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10 August 2017

Michael Andreeff

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10 August 2017

Mark F Munsell

1 reference

10 August 2017

David M Sabatini

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10 August 2017

Dos D Sarbassov

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10 August 2017

Ismael J Samudio

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10 August 2017

Zhihong Zeng

1 reference

10 August 2017

Karen W L Yee

1 reference

10 August 2017

C Ellen Jackson

series ordinal

1 reference

10 August 2017

Francis J Giles

series ordinal

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10 August 2017

language of work or name

English

0 references

publication date

19 December 2006

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10 August 2017

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10 August 2017

volume

109

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10 August 2017

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10 August 2017

page(s)

3509-3512

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Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

10 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852241

TOR signaling in growth and metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852241

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852241

mTOR and cancer: reason for dancing at the crossroads?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852241

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852241

The TOR pathway: a target for cancer therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852241

Nuclear factor-kappaB modulation as a therapeutic approach in hematologic malignancies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852241

Mammalian target of rapamycin inhibition as therapy for hematologic malignancies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852241

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852241

A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852241

Mutational analysis of the tumour suppressor gene MMAC1/PTEN in malignant myeloid disorders

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852241

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852241

Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852241

Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17179228

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2006-06-030833

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10 August 2017

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10 August 2017

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