(Q35630861)

English

Dipeptidyl peptidase-4 inhibition ameliorates Western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function

scientific article published on 20 January 2015

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scholarly article

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Europe PubMed Central

PubMed publication ID

9 August 2017

Dipeptidyl peptidase-4 inhibition ameliorates Western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

insulin resistance

1 reference

based on heuristic

inferred from title

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inferred from title

Elizabeth Parks

object named as

Elizabeth J Parks

10

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David A Ford

3

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object named as

John P Thyfault

9

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author name string

Annayya R Aroor

1

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Europe PubMed Central

PubMed publication ID

9 August 2017

Javad Habibi

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Ravi Nistala

4

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Europe PubMed Central

PubMed publication ID

9 August 2017

Guido Lastra

5

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Europe PubMed Central

PubMed publication ID

9 August 2017

Camila Manrique

6

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Merlow M Dunham

7

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Kaitlin D Ford

8

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

James R Sowers

11

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Europe PubMed Central

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9 August 2017

R Scott Rector

12

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Europe PubMed Central

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9 August 2017

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publication date

20 January 2015

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Europe PubMed Central

PubMed publication ID

9 August 2017

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Europe PubMed Central

PubMed publication ID

9 August 2017

64

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Europe PubMed Central

PubMed publication ID

9 August 2017

6

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Europe PubMed Central

PubMed publication ID

9 August 2017

1988-2001

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Dipeptidyl peptidase inhibition prevents diastolic dysfunction and reduces myocardial fibrosis in a mouse model of Western diet induced obesity

1 reference

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12 July 2018

Prevention of obesity-induced renal injury in male mice by DPP4 inhibition

1 reference

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12 July 2018

Effect of diet on expression of genes involved in lipid metabolism, oxidative stress, and inflammation in mouse liver-insights into mechanisms of hepatic steatosis

1 reference

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12 July 2018

The role of diet and nutritional intervention for the management of patients with NAFLD.

1 reference

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12 July 2018

Nonalcoholic Fatty liver: a possible new target for type 2 diabetes prevention and treatment

1 reference

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12 July 2018

Impact of various exercise modalities on hepatic mitochondrial function

1 reference

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12 July 2018

Sugar, uric acid, and the etiology of diabetes and obesity.

1 reference

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12 July 2018

Non-alcoholic fatty liver disease (NAFLD): a tale of fat and sugar?

1 reference

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12 July 2018

High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

The place of GLP-1-based therapy in diabetes management: differences between DPP-4 inhibitors and GLP-1 receptor agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Dipeptidyl peptidase-4 inhibitor attenuates hepatic fibrosis via suppression of activated hepatic stellate cell in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Dietary fructose in nonalcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Selective hepatic insulin resistance in a murine model heterozygous for a mitochondrial trifunctional protein defect

1 reference

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12 July 2018

Potential of incretin-based therapies for non-alcoholic fatty liver disease

1 reference

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12 July 2018

Obesity-related alterations in cardiac lipid profile and nondipping blood pressure pattern during transition to diastolic dysfunction in male db/db mice

1 reference

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12 July 2018

GLP-1 receptor activation inhibits VLDL production and reverses hepatic steatosis by decreasing hepatic lipogenesis in high-fat-fed APOE*3-Leiden mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Effects of insulin resistance and hepatic lipid accumulation on hepatic mRNA expression levels of apoB, MTP and L-FABP in non-alcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Fructose and risk of cardiometabolic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function

1 reference

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12 July 2018

Diacylglycerol activation of protein kinase Cε and hepatic insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Intrahepatic diacylglycerol content is associated with hepatic insulin resistance in obese subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Mechanisms for insulin resistance: common threads and missing links

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Exendin-4 improves steatohepatitis by increasing Sirt1 expression in high-fat diet-induced obese C57BL/6J mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

The Role of Overweight and Obesity in the Cardiorenal Syndrome

1 reference

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12 July 2018

Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Elevated glucose represses liver glucokinase and induces its regulatory protein to safeguard hepatic phosphate homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Increased diacylglycerols characterize hepatic lipid changes in progression of human nonalcoholic fatty liver disease; comparison to a murine model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Diet-Induced Adipose Tissue Inflammation and Liver Steatosis Are Prevented by DPP-4 Inhibition in Diabetic Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Serum Dipeptidyl Peptidase-4 Activity in Insulin Resistant Patients with Non-Alcoholic Fatty Liver Disease: A Novel Liver Disease Biomarker

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

The role of mitochondria in the pathogenesis of type 2 diabetes

1 reference

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Prevalence and trends in obesity among US adults, 1999-2008

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid beta-oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Glucose metabolism in vivo in four commonly used inbred mouse strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

The role of gut hormones in glucose homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

12 July 2018

Liquid fructose downregulates Sirt1 expression and activity and impairs the oxidation of fatty acids in rat and human liver cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

25 September 2018

Dipeptidyl peptidase IV (DDP IV) in NASH patients.

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25 September 2018

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25 September 2018

Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

25 September 2018

Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339.

1 reference

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25 September 2018

Quantitative analysis and molecular species fingerprinting of triacylglyceride molecular species directly from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry

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25 September 2018

Association of nonalcoholic fatty liver disease with insulin resistance.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439570

25 September 2018

The DPP-4 inhibitor MK0626 and exercise protect islet function in early pre-diabetic kkay mice

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased hepatic expression of dipeptidyl peptidase-4 in non-alcoholic fatty liver disease and its association with insulin resistance and glucose metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/25605806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acyl chain dependence of diacylglycerol activation of protein kinase C activity in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/25605806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct effects of fructose metabolism on fatty acid oxidation in a recombined rat liver mitochondria-high speed supernatant system

1 reference

https://pubmed.ncbi.nlm.nih.gov/25605806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB14-0804

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

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