(Q35603395)

25811318

9 August 2017

title

Severe insulin resistance alters metabolism in mesenchymal progenitor cells (English)

1 reference

9 August 2017

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25811318%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25811318%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Chad Cowan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25811318%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Bharti Balhara

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25811318%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Alison Burkart

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25811318%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Youn-Kyoung Lee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25811318%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

C Ronald Kahn

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25811318%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Mary-Elizabeth Patti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25811318%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

language of work or name

English

0 references

publication date

26 March 2015

1 reference

9 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25811318%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

156

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7 June 2020

issue

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7 June 2020

page(s)

2039-2048

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25811318%20AND%20SRC:MED&resulttype=core&format=json

Genetic insulin resistance is a potent regulator of gene expression and proliferation in human iPS cells

7 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Energy metabolism and energy-sensing pathways in mammalian embryonic and adult stem cell fate

12 July 2018

1 reference

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Programming human pluripotent stem cells into white and brown adipocytes.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Mitochondrial dysfunction in patients with primary congenital insulin resistance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Epigenetic memory in induced pluripotent stem cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Severe insulin resistance and intrauterine growth deficiency associated with haploinsufficiency for INSR and CHN2: new insights into synergistic pathways involved in growth and metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Markers of mitochondrial biogenesis and metabolism are lower in overweight and obese insulin-resistant subjects.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Functional characterization of a novel insulin receptor mutation contributing to Rabson-Mendenhall syndrome.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Mitochondrial dysfunction and type 2 diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Gene expression in human cells with mutant insulin receptors.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Genotype-phenotype correlation in inherited severe insulin resistance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Leprechaunism/Donohue syndrome/insulin receptor gene mutations: a syndrome delineation story from clinicopathological description to molecular understanding

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

A syndrome of insulin resistance resembling leprechaunism in five sibs of consanguineous parents

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Endocrine-metabolic relationships in patients with leprechaunism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Fibroblasts from a Patient with Leprechaunism Are Resistant to Insulin, Epidermal Growth Factor, and Somatomedin C*

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Leprechaunism: an inherited defect in a high-affinity insulin receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Leprechaunism: report of two cases and review.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Insulin receptor function in fibroblasts from patients with leprechaunism. Differential alterations in binding, autophosphorylation, kinase activity, and receptor-mediated internalization

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Epidermal growth factor receptor defects in leprechaunism. A multiple growth factor-resistant syndrome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Insulin-receptor gene and its expression in patients with insulin resistance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Human diabetes associated with a deletion of the tyrosine kinase domain of the insulin receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Five mutant alleles of the insulin receptor gene in patients with genetic forms of insulin resistance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Substitution of arginine for histidine at position 209 in the alpha-subunit of the human insulin receptor. A mutation that impairs receptor dimerization and transport of receptors to the cell surface

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Lilly Lecture: molecular mechanisms of insulin resistance. Lessons from patients with mutations in the insulin-receptor gene

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Impact of exercise training on insulin sensitivity, physical fitness, and muscle oxidative capacity in first-degree relatives of type 2 diabetic patients

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Impaired generation of reactive oxygen species in leprechaunism through downregulation of Nox4.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Cell culture studies on patients with extreme insulin resistance. I. Receptor defects on cultured fibroblasts.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Insulin-resistant diabetes associated with partial deletion of insulin-receptor gene

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Reduced Expression of Nuclear-Encoded Genes Involved in Mitochondrial Oxidative Metabolism in Skeletal Muscle of Insulin-Resistant Women With Polycystic Ovary Syndrome

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430624

Defects in human insulin receptor gene expression

15 November 2018

1 reference

12 December 2020

Growth factor receptor regulation in the Minn-1 leprechaun: defects in both insulin receptor and epidermal growth factor receptor gene expression

1 reference

12 December 2020

Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study

1 reference

12 December 2020

Homozygosity for a null allele of the insulin receptor gene in a patient with leprechaunism

1 reference

12 December 2020

Molecular analysis of the insulin receptor gene for prenatal diagnosis of leprechaunism in two families

1 reference

12 December 2020

Leprechaunism: a euphemism for a rare familial disorder

1 reference

12 December 2020

Leprechaunism. A report of two new cases

1 reference

12 December 2020

Identifiers

DOI

10.1210/EN.2014-1403

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25811318%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25811318%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

25811318

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25811318%20AND%20SRC:MED&resulttype=core&format=json