(Q35696798)

9 August 2017

title

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks (English)

1 reference

9 August 2017

0 references

Aviv Regev

1 reference

9 August 2017

Rahul Satija

0 references

Nir Hacohen

object named as

Nir Hacohen

0 references

Itay Tirosh

object named as

Itay Tirosh

1 reference

9 August 2017

Raktima Raychowdhury

1 reference

9 August 2017

Dariusz Przybylski

1 reference

9 August 2017

Neville E Sanjana

0 references

Steven A Carr

1 reference

9 August 2017

Chun Jimmie Ye

1 reference

9 August 2017

Thomas M Eisenhaure

1 reference

9 August 2017

Philipp Mertins

1 reference

9 August 2017

Oren Parnas

1 reference

9 August 2017

Marko Jovanovic

1 reference

9 August 2017

Rebecca H Herbst

1 reference

9 August 2017

Atray Dixit

1 reference

9 August 2017

Randall J Platt

1 reference

9 August 2017

Ophir Shalem

1 reference

9 August 2017

Feng Zhang

1 reference

9 August 2017

language of work or name

English

0 references

publication date

16 July 2015

1 reference

full work available at URL

9 August 2017

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522370

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published in

Cell

1 reference

9 August 2017

volume

162

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9 August 2017

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9 August 2017

page(s)

675-686

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The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

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12 July 2018

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Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

12 July 2018

1 reference

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CRISPR-Cas9 knockin mice for genome editing and cancer modeling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Improved vectors and genome-wide libraries for CRISPR screening

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Measuring error rates in genomic perturbation screens: gold standards for human functional genomics

12 July 2018

1 reference

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Single-cell RNA-seq reveals dynamic paracrine control of cellular variation

12 July 2018

1 reference

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Genome-scale CRISPR-Cas9 knockout screening in human cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Genetic screens in human cells using the CRISPR-Cas9 system

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

GWAS Central: a comprehensive resource for the comparison and interrogation of genome-wide association studies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Smart-seq2 for sensitive full-length transcriptome profiling in single cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

The DNA-binding factor Ctcf critically controls gene expression in macrophages.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

ER stress induced impaired TLR signaling and macrophage differentiation of human monocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Compensatory dendritic cell development mediated by BATF-IRF interactions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Suppression of the antiviral response by an influenza histone mimic

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Strategies to discover regulatory circuits of the mammalian immune system

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Recent insights into cerebral cavernous malformations: a complex jigsaw puzzle under construction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

The Paf1 complex: platform or player in RNA polymerase II transcription?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Haploid genetic screens in human cells identify host factors used by pathogens

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Congenital disorders of glycosylation: an update on defects affecting the biosynthesis of dolichol-linked oligosaccharides

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Transcriptional regulatory circuits: predicting numbers from alphabets

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Control of inducible gene expression by signal-dependent transcriptional elongation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

AU-rich RNA-binding induces changes in the quaternary structure of AUH

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Deacetylase activity is required for STAT5-dependent GM-CSF functional activity in macrophages and differentiation to dendritic cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Differential expression of IFN regulatory factor 4 gene in human monocyte-derived dendritic cells and macrophages

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

The parafibromin tumor suppressor protein is part of a human Paf1 complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

KEGG: kyoto encyclopedia of genes and genomes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

STATs and Gene Regulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

AUH, a gene encoding an AU-specific RNA binding protein with intrinsic enoyl-CoA hydratase activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Yeast mutants deficient in protein glycosylation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Plasma filtration in Couette flow membrane devices

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Precision mapping of an in vivo N-glycoproteome reveals rigid topological and sequence constraints.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Minimizing the risk of reporting false positives in large-scale RNAi screens

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522370

Regulation of dendritic cell differentiation and subset distribution by the zinc finger protein CTCF

7 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26189680

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential regulation of tumor necrosing factor-alpha (TNF-alpha) and interleukin-10 (IL-10) secretion by protein kinase and phosphatase inhibitors in human alveolar macrophages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26189680

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2015.06.059

1 reference

9 August 2017

1 reference

9 August 2017

1 reference