(Q35663680)

9 August 2017

title

Genetic evidence for functional dependency of p18Ink4c on Cdk4. (English)

1 reference

9 August 2017

Xin-Hai Pei

1 reference

9 August 2017

Feng Bai

1 reference

9 August 2017

Tateki Tsutsui

1 reference

9 August 2017

Hiroaki Kiyokawa

1 reference

9 August 2017

Yue Xiong

1 reference

9 August 2017

language of work or name

English

0 references

publication date

1 August 2004

1 reference

Molecular and Cellular Biology

9 August 2017

published in

1 reference

9 August 2017

1 reference

9 August 2017

1 reference

9 August 2017

page(s)

6653-6664

1 reference

p27Kip1 and p21Cip1 Are Not Required for the Formation of Active D Cyclin-cdk4 Complexes

9 August 2017

cites work

1 reference

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Genetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell number

12 July 2018

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Haploinsufficiency of p18(INK4c) sensitizes mice to carcinogen-induced tumorigenesis

12 July 2018

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Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system

12 July 2018

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Genetic evidence for the interactions of cyclin D1 and p27(Kip1) in mice

12 July 2018

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Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

12 July 2018

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Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

12 July 2018

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Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis

12 July 2018

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INK4d-deficient mice are fertile despite testicular atrophy

12 July 2018

1 reference

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Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

12 July 2018

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INK4 cell cycle inhibitors direct transcriptional inactivation of NF-kappaB

12 July 2018

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Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

12 July 2018

1 reference

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The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

12 July 2018

1 reference

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Complete inhibition of Cdk/cyclin by one molecule of p21(Cip1)

12 July 2018

1 reference

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CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis

12 July 2018

1 reference

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A unique pattern of photoreceptor degeneration in cyclin D1 mutant mice

12 July 2018

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Hormone-induced proliferation and differentiation of granulosa cells: a coordinated balance of the cell cycle regulators cyclin D2 and p27Kip1

12 July 2018

1 reference

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p107 is a suppressor of retinoblastoma development in pRb-deficient mice

12 July 2018

1 reference

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Coupled transcriptional and translational control of cyclin-dependent kinase inhibitor p18INK4c expression during myogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

New functional activities for the p21 family of CDK inhibitors

12 July 2018

1 reference

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A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

12 July 2018

1 reference

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Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

12 July 2018

1 reference

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Physical interaction of the retinoblastoma protein with human D cyclins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

WAF1, a potential mediator of p53 tumor suppression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

p21-containing cyclin kinases exist in both active and inactive states

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Cell cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Cyclin D1 provides a link between development and oncogenesis in the retina and breast

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Inhibition of cyclin-dependent kinases by p21

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Growth suppression by p16ink4 requires functional retinoblastoma protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Radiation-induced cell cycle arrest compromised by p21 deficiency

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Effects of an Rb mutation in the mouse

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Cell cycle control: a complex issue

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Pituitary hypoplasia and lactotroph dysfunction in mice deficient for cyclin-dependent kinase-4.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

p27Kip1 and p57Kip2 regulate proliferation in distinct retinal progenitor cell populations.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=444851

Cooperative tumorigenic effects of germline mutations in Rb and p53

15 November 2018

1 reference

12 December 2020

Heterozygous Rb-1 delta 20/+mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance

1 reference

12 December 2020

Requirements for cell cycle arrest by p16INK4a

1 reference

12 December 2020

The absence of p27Kip1, an inhibitor of G1 cyclin-dependent kinases, uncouples differentiation and growth arrest during the granulosa->luteal transition

1 reference

12 December 2020

10.1128/MCB.24.15.6653-6664.2004

Identifiers

DOI

1 reference

9 August 2017

1 reference

9 August 2017

1 reference