(Q35647543)

9 August 2017

title

Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age. (English)

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9 August 2017

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Irving L Weissman

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9 August 2017

Wendy W Pang

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9 August 2017

Elizabeth A Price

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9 August 2017

Debashis Sahoo

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9 August 2017

Isabel Beerman

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9 August 2017

William J Maloney

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9 August 2017

Derrick J Rossi

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9 August 2017

Stanley L Schrier

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9 August 2017

language of work or name

English

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publication date

28 November 2011

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Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

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inferred from page(s)

published in

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9 August 2017

volume

108

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9 August 2017

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9 August 2017

page(s)

20012-20017

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Stem cells and the aging hematopoietic system

9 August 2017

cites work

1 reference

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Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

27 July 2018

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27 July 2018

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Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.

27 July 2018

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Boolean implication networks derived from large scale, whole genome microarray datasets

27 July 2018

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Determining the influence of telomere dysfunction and DNA damage on stem and progenitor cell aging: what markers can we use?

27 July 2018

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Hematopoietic fingerprints: an expression database of stem cells and their progeny

27 July 2018

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Long-term propagation of distinct hematopoietic differentiation programs in vivo

27 July 2018

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Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

27 July 2018

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DNA repair is limiting for haematopoietic stem cells during ageing

27 July 2018

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Age-dependent increase in side population distribution within hematopoiesis: implications for our understanding of the mechanism of aging

27 July 2018

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Hematopoietic stem cells: the paradigmatic tissue-specific stem cell

27 July 2018

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Normal and neoplastic stem cells.

27 July 2018

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Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice

27 July 2018

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The relationship of patient age to the pathobiology of the clonal myeloid diseases

27 July 2018

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Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished lymphoid progeny with impaired IL-7 responsiveness

27 July 2018

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27 July 2018

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Ageing, repetitive genomes and DNA damage

27 July 2018

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27 July 2018

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Prospective isolation of human clonogenic common myeloid progenitors

27 July 2018

1 reference

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Significance analysis of microarrays applied to the ionizing radiation response

27 July 2018

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Age-associated characteristics of murine hematopoietic stem cells

27 July 2018

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Transplantation of highly purified CD34+Thy-1+ hematopoietic stem cells in patients with metastatic breast cancer

27 July 2018

1 reference

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Evidence for a continuous decline in haemopoietic cell function from birth: application to evaluating bone marrow failure in children

27 July 2018

1 reference

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Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice.

27 July 2018

1 reference

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The aging of hematopoietic stem cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250139

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250139

Analysis of human hematopoietic stem cell populations

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250139

Bone marrow stromal cell lines with lymphopoietic activity express high levels of a pre-B neoplasia-associated molecule.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250139

The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250139

Isolation of a candidate human hematopoietic stem-cell population

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250139

Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250139

A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250139

Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250139

Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250139

Cell intrinsic alterations underlie hematopoietic stem cell aging.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250139

Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250139

The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250139

Acquired skewing of X‐chromosome inactivation patterns in myeloid cells of the elderly suggests stochastic clonal loss with age

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250139

Restoration of TRAIL-induced apoptosis in a caspase-8-deficient neuroblastoma cell line by stable re-expression of caspase-8.

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1116110108

21 January 2018

1 reference

12 December 2020

Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age

1 reference

12 December 2020

Age and stress related phenotypical changes in bone marrow CD34+ cells

1 reference

12 December 2020

The anemia of senescence

1 reference

12 December 2020

Thy-1-expressing CD34+ human cells express multiple hematopoietic potentialities in vitro and in SCID-hu mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1116110108

1 reference

9 August 2017

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1 reference

9 August 2017

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