(Q35599161)

9 August 2017

title

Evidence for cytokine-inducible nitric oxide synthesis from L-arginine in patients receiving interleukin-2 therapy (English)

1 reference

9 August 2017

J B Hibbs

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9 August 2017

C Westenfelder

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9 August 2017

R Taintor

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9 August 2017

Z Vavrin

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9 August 2017

C Kablitz

1 reference

9 August 2017

R L Baranowski

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9 August 2017

J H Ward

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9 August 2017

R L Menlove

1 reference

9 August 2017

M P McMurry

1 reference

9 August 2017

J P Kushner

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9 August 2017

language of work or name

English

0 references

publication date

1 March 1992

1 reference

Journal of Clinical Investigation

9 August 2017

published in

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9 August 2017

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9 August 2017

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9 August 2017

page(s)

867-877

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Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

9 August 2017

cites work

1 reference

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12 July 2018

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Nitrate biosynthesis in man

12 July 2018

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Mammalian nitrate biosynthesis: incorporation of 15NH3 into nitrate is enhanced by endotoxin treatment

12 July 2018

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Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide

12 July 2018

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Escherichia coli endotoxin injections potentiate experimental ischemic renal injury

12 July 2018

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Endotoxemic acute renal failure in awake rats.

12 July 2018

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Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

12 July 2018

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Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

12 July 2018

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NIH conference. New approaches to the immunotherapy of cancer using interleukin-2.

12 July 2018

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Induction of circulating tumor necrosis factor (TNF alpha) as the mechanism for the febrile response to interleukin-2 (IL-2) in cancer patients

12 July 2018

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Nitric oxide: a cytotoxic activated macrophage effector molecule

12 July 2018

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Circulating cytokines in patients with metastatic cancer treated with recombinant interleukin 2 and lymphokine-activated killer cells

12 July 2018

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Vascular endothelial cells synthesize nitric oxide from L-arginine

12 July 2018

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Human interleukin 2: molecular biology, physiology and clinical possibilities

12 July 2018

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Atrial natriuretic peptide protects against acute ischemic renal failure in the rat

12 July 2018

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Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst

12 July 2018

1 reference

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Passive immunization against tumor necrosis factor partially abrogates interleukin 2 toxicity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

L-arginine is a precursor for nitrate biosynthesis in humans

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Macrophage cytotoxicity against schistosomula of Schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Heme-dependent activation of soluble guanylate cyclase by nitric oxide: regulation of enzyme activity by porphyrins and metalloporphyrins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Formation and release of nitric oxide from human neutrophils and HL-60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B4.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Correlation between clinical response to interleukin 2 therapy and sustained production of tumor necrosis factor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Glomerular endothelial cells respond to calcium-mobilizing agonists with release of EDRF.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Effects of endothelium-derived relaxing factor and nitric oxide on rat mesangial cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblasts.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Alterations of ribonucleotide reductase activity following induction of the nitrite-generating pathway in adenocarcinoma cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Endothelial cell production of nitrogen oxides in response to interferon gamma in combination with tumor necrosis factor, interleukin-1, or endotoxin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Endothelial derived relaxing factor controls renal hemodynamics in the normal rat kidney

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Tumor necrosis factor alpha activates soluble guanylate cyclase in bovine glomerular mesangial cells via an L-arginine-dependent mechanism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Tumor necrosis factor and granulocyte macrophage-colony stimulating factor stimulate human macrophages to restrict growth of virulent Mycobacterium avium and to kill avirulent M. avium: killing effector mechanism depends on the generation of reactiv

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Role of nitric oxide synthesis in macrophage antimicrobial activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Localization of nitric oxide synthase indicating a neural role for nitric oxide

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Stoichiometry of the reaction of oxyhemoglobin with nitrite

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Induction of endogenous cytokine-mRNA in circulating peripheral blood mononuclear cells by IL-2 administration to cancer patients.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

IFN-gamma-activated macrophages: detection by electron paramagnetic resonance of complexes between L-arginine-derived nitric oxide and non-heme iron proteins

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442932

L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells

26 September 2018

1 reference

12 December 2020

Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism

1 reference

12 December 2020

Cytokines induce an L-arginine-dependent effector system in nonmacrophage cells

1 reference

12 December 2020

Effects of interleukin-2 on renal function in patients receiving immunotherapy for advanced cancer

1 reference

12 December 2020

Effect of vanadate on renal tubular function in rats

1 reference

12 December 2020

Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man

1 reference

12 December 2020

The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium

1 reference

12 December 2020

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

1 reference

12 December 2020

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production

1 reference

12 December 2020

Interferon-gamma and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages

1 reference

12 December 2020

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

1 reference

12 December 2020

Effects of interleukin-2 immunotherapy on renal function

1 reference

12 December 2020

Relative significance of dietary sources of nitrate and nitrite

1 reference

12 December 2020

Effect of intravenous infusion of atriopeptin 3 on immediate renal allograft function

1 reference

12 December 2020

Killing of Leishmania parasites in activated murine macrophages is based on an L-arginine-dependent process that produces nitrogen derivatives

1 reference

12 December 2020

Adoptive Immunotherapy of Established Pulmonary Metastases with LAK Cells and Recombinant Interleukin-2

1 reference

12 December 2020

A rapid method for the assay of nitrate in urine using the nitrate reductase enzyme of Escherichia coli

1 reference

12 December 2020

Nitrate synthesis in the germfree and conventional rat

1 reference

12 December 2020

Renal tubular function in glycerol-induced acute renal failure

1 reference

12 December 2020

Lysis of fresh and cultured autologous tumor by human lymphocytes cultured in T-cell growth factor

1 reference

12 December 2020

Acute renal failure in the 1980s: the importance of septic shock and of endotoxaemia

1 reference

12 December 2020

Gas chromatography/mass spectrometric determination of [15N]urea in plasma and application to urea metabolism study

1 reference

12 December 2020

Adoptive immunotherapy of human cancer: the cytokine cascade and monocyte activation following high-dose interleukin 2 bolus treatment

1 reference

12 December 2020

Reactive oxygen metabolites in endotoxin-induced acute renal failure in rats

1 reference

12 December 2020

Modulation of nitrogen oxide synthesis in vivo: NG-monomethyl-L-arginine inhibits endotoxin-induced nitrate/nitrate biosynthesis while promoting hepatic damage

1 reference

12 December 2020

Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine

1 reference

12 December 2020

Volume homeostasis in calves with artificial atria and ventricles

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI115666

1 reference

9 August 2017

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9 August 2017

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