(Q35596780)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Matsuoka K

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Inoue N

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Sato T

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Okamoto S

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Hisamatsu T

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Kishi Y

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Hitotsumatsu O

1 reference

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31 December 2019

Ogata H

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Koganei K

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Fukushima T

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Kanai T

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Watanabe M

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Ishii H

1 reference

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31 December 2019

Hibi T

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

language of work or name

English

0 references

publication date

1 September 2004

1 reference

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31 December 2019

1 reference

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31 December 2019

volume

1 reference

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31 December 2019

issue

1 reference

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31 December 2019

page(s)

1303-1308

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

Combined budesonide and antibiotic therapy for active Crohn's disease: a randomized controlled trial

31 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

The role of Th1/Th2 polarization in mucosal immunity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Immunoregulation in the gut: success and failures in human disease.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Up-regulation of the IL-12 receptor beta 2 chain in Crohn's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Type I interferons and T helper development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Transcriptional regulation of Th1/Th2 polarization

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Lineage commitment in the immune system: the T helper lymphocyte grows up.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

A novel transcription factor, T-bet, directs Th1 lineage commitment

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Infliximab for the treatment of fistulas in patients with Crohn's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Inflammatory bowel disease: etiology and pathogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Interleukin-10-deficient mice develop chronic enterocolitis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Incidence of inflammatory bowel disease in northern France (1988-1990).

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Antibodies to interleukin 12 abrogate established experimental colitis in mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Classification of inflammatory bowel disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Role of T-bet in commitment of TH1 cells before IL-12-dependent selection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Bioactive IL-18 expression is up-regulated in Crohn's disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Comparison of enteral nutrition and drug treatment in active Crohn's disease. Results of the European Cooperative Crohn's Disease Study. IV.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774174

Repeated antigen exposure is necessary for the differentiation, but not the initial proliferation, of naive CD4(+) T cells

26 September 2018

1 reference

12 December 2020

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

1 reference

12 December 2020

Th1-mediated intestinal inflammation in Crohn's disease may be induced by activation of lamina propria lymphocytes through synergistic stimulation of interleukin-12 and interleukin-18 without T cell receptor engagement

1 reference

12 December 2020

Interleukin 18 is a potent proliferative factor for intestinal mucosal lymphocytes in Crohn's disease

1 reference

12 December 2020

Analysis of intestinal lymphocytes in mouse colitis mediated by transfer of CD4+, CD45RBhigh T cells to SCID recipients

1 reference

12 December 2020

Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells

1 reference

12 December 2020

Identifiers

DOI

10.1136/GUT.2003.024190

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

PubMed publication ID

15306590

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15306590%20AND%20SRC:MED&resulttype=core&format=json