(Q35486021)

8 August 2017

title

Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice (English)

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8 August 2017

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Jun Yoshino

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8 August 2017

Kathryn F Mills

series ordinal

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8 August 2017

Myeong Jin Yoon

series ordinal

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8 August 2017

Shin-ichiro Imai

series ordinal

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8 August 2017

publication date

1 October 2011

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8 August 2017

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8 August 2017

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8 August 2017

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8 August 2017

page(s)

528-536

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Obesity, insulin resistance and diabetes: sex differences and role of oestrogen receptors.

8 August 2017

cites work

1 reference

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A nutrient-sensitive interaction between Sirt1 and HNF-1α regulates Crp expression

27 July 2018

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Interleukin-1beta may mediate insulin resistance in liver-derived cells in response to adipocyte inflammation.

27 July 2018

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Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

27 July 2018

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Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

27 July 2018

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27 July 2018

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"Clocks" in the NAD World: NAD as a metabolic oscillator for the regulation of metabolism and aging

27 July 2018

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S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis.

27 July 2018

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Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt

27 July 2018

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Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice

27 July 2018

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Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme

27 July 2018

1 reference

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Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1

27 July 2018

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Inflammation and insulin resistance

27 July 2018

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Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

27 July 2018

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The molecular basis for oxidative stress-induced insulin resistance

27 July 2018

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PAGE: parametric analysis of gene set enrichment

27 July 2018

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Mitochondrial dysfunction and type 2 diabetes

27 July 2018

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Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

27 July 2018

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FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis

27 July 2018

1 reference

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Effects of ageing on insulin secretion and action

27 July 2018

1 reference

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Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders

27 July 2018

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Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice.

26 September 2018

1 reference

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Hepatic lipin 1beta expression is diminished in insulin-resistant obese subjects and is reactivated by marked weight loss

26 September 2018

1 reference

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Epidemiologic and economic consequences of the global epidemics of obesity and diabetes

26 September 2018

1 reference

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Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204926

How obesity causes diabetes: not a tall tale

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204926

TNF-alpha and insulin resistance: summary and future prospects

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3204926

10.1016/J.CMET.2011.08.014

26 September 2018

Identifiers

DOI

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8 August 2017

1 reference

8 August 2017

1 reference