(Q35213803)

7 August 2017

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title

How we detect microbes and respond to them: the Toll-like receptors and their transducers (English)

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7 August 2017

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7 August 2017

Beutler B

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7 August 2017

Du X

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7 August 2017

Ulevitch RJ

series ordinal

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7 August 2017

publication date

1 July 2003

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Journal of Leukocyte Biology

7 August 2017

published in

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7 August 2017

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7 August 2017

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7 August 2017

page(s)

479-485

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Lipid A: Chemical Structure and Biological Activity

7 August 2017

cites work

1 reference

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Adjuvant activity of bacterial peptidoglycans on the production of delayed hypersensitivity and on antibody response

21 January 2018

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CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

21 January 2018

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Genetic and Physical Mapping of theLpsLocus: Identification of the Toll-4 Receptor as a Candidate Gene in the Critical Region

21 January 2018

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

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MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

21 January 2018

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Essential role of MD-2 in LPS responsiveness and TLR4 distribution

21 January 2018

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Chromosomal localization of TIL, a gene encoding a protein related to the Drosophila transmembrane receptor Toll, to human chromosome 4p14.

21 January 2018

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Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0203082

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0203082

A family of human receptors structurally related to Drosophila Toll

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0203082

TLR6: A novel member of an expanding toll-like receptor family

21 January 2018

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Initial sequencing and analysis of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0203082

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

21 January 2018

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Interleukin-6 induction by tumor necrosis factor and interleukin-1 in human fibroblasts involves activation of a nuclear factor binding to a kappa B-like sequence

21 January 2018

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Insect immunity: the diptericin promoter contains multiple functional regulatory sequences homologous to mammalian acute-phase response elements.

21 January 2018

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Drosophila innate immunity: an evolutionary perspective

21 January 2018

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Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation

21 January 2018

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Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide

21 January 2018

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Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2

21 January 2018

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Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition

21 January 2018

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Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

21 January 2018

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The extracellular toll-like receptor 2 domain directly binds peptidoglycan derived from Staphylococcus aureus

21 January 2018

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The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.

21 January 2018

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Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

21 January 2018

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The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

21 January 2018

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Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

21 January 2018

1 reference

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The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

21 January 2018

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A Toll-like receptor recognizes bacterial DNA

21 January 2018

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

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Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0203082

Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

TIRAP: an adapter molecule in the Toll signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

IRF3 mediates a TLR3/TLR4-specific antiviral gene program

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

Innate immune recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0203082

The plasticity of dendritic cell responses to pathogens and their components

21 January 2018

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1189/JLB.0203082

Cell activation by Porphyromonas gingivalis lipid A molecule through Toll-like receptor 4- and myeloid differentiation factor 88-dependent signaling pathway

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1189/JLB.0203082

Insect immunity: developmental and inducible activity of the Drosophila diptericin promoter

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1189/JLB.0203082

Unresponsiveness of MyD88-deficient mice to endotoxin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1189/JLB.0203082

How does the immune system distinguish self from nonself?

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1189/JLB.0203082

Adjuvant effect of cord factor, a mycobacterial lipid

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1189/JLB.0203082

Identifiers

DOI

10.1189/JLB.0203082

1 reference

7 August 2017

1 reference