(Q35208007)

English

Insulin receptors in isolated human adipocytes. Characterization by photoaffinity labeling and evidence for internalization and cellular processing

scientific article published on December 1, 1983

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Insulin receptors in isolated human adipocytes. Characterization by photoaffinity labeling and evidence for internalization and cellular processing (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

affinity labels

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

Jerrold M. Olefsky

5

object named as

J M Olefsky

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

author name string

P. Berhanu

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

O. G. Kolterman

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

A. Baron

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

P. Tsai

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

D. Brandenburg

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

language of work or name

0 references

publication date

1 December 1983

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

full work available at URL

http://www.jci.org/articles/view/111160/files/pdf

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

https://europepmc.org/articles/PMC437036

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

https://europepmc.org/articles/PMC437036?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

http://www.jci.org/articles/view/111160/files/pdf

1 reference

10.1172/JCI111160

https://api.crossref.org/works/10.1172/JCI111160

7 October 2023

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

72

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

1958-1970

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Variations of glucose metabolism by fat cells from three adipose depots of the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Internalization and molecular processing of insulin receptors in isolated rat adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Internalization and intracellular processing of insulin and insulin receptors in adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Evidence for insulin-induced internalization and degradation of insulin receptors in rat adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Biochemical and morphological evidence that the insulin receptor is internalized with insulin in hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Effect of chloroquine on the internalization of 125I-insulin into subcellular fractions of rat liver. Evidence for an effect of chloroquine on Golgi elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Mechanism of the postreceptor defect in insulin action in human obesity. Decrease in glucose transport system activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

LIlly lecture 1980. Insulin resistance and insulin action. An in vitro and in vivo perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Characterization of insulin receptor subunits in brain and other tissues by photoaffinity labeling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Effects of insulin incubation on insulin binding, glucose transport, and insulin degradation by isolated rat adipocytes. Evidence for hormone-induced desensitization at the receptor and postreceptor level

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Mechanisms of insulin resistance in human obesity: evidence for receptor and postreceptor defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Lysosomal degradation of receptor-bound 125I-labeled insulin by rat adipocytes: its characterization and dissociation from the short-term biologic effects of insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Biosynthetic labeling of insulin receptor: studies of subunits in cultured human IM-9 lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Insulin receptor: evidence that it is a protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Commentary. Lysosomotropic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Methods for the determination of adipose cell size in man and animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Inactivation of lysosomal function in normal cultured human fibroblasts by chloroquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Defect in insulin binding to receptors in obese man. Amelioration with calorie restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Insulin binding in diabetes. Relationships with plasma insulin levels and insulin sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

The insulin receptor: its role in insulin resistance of obesity and diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Insulin induced changes in insulin binding and insulin-sensitivity of adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

The pathogenic role of an insulin-receptor defect in diabetes mellitus of the obese

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Effects of lysosomotropic agents on insulin interactions with adipocytes. Evidence for a lysosomal pathway for insulin processing and degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Insulin Sensitivity and Insulin Binding to Monocytes in Maturity-Onset Diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Molecular mechanism of mitogen action: processing of receptor induced by epidermal growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Insulin receptor: covalent labeling and identification of subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Decreased insulin binding to adipocytes and circulating monocytes from obese subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Inhibition of proteolytic degradation of low density lipoprotein in human fibroblasts by chloroquine, concanavalin A, and Triton WR 1339

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

A desensitized state of the beta adrenergic receptor not associated with high-affinity agonist occupancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Purification and properties of the human placental insulin receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

26 September 2018

Differences at the Receptor and Postreceptor Levels Between Human Omental and Subcutaneous Adipose Tissue in the Action of Insulin on Lipolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

26 September 2018

Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

26 September 2018

Down regulation of insulin receptors in primary cultures of adult rat hepatocytes in monolayer

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stoichiometric binding and regulation of insulin receptors on human diploid fibroblasts using physiologic insulin levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of photoaffinity labeled insulin receptor proteins by linear polyacrylamide gradient gel electrophoresis under non-denaturing conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Covalent linking of photoreactive insulin to adipocytes produces a prolonged signal

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unimpaired signal transduction by the adipocyte insulin receptor following its partial proteolytic fragmentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catecholamine-induced desensitization in turkey erythrocytes: cAMP mediated impairment of high affinity agonist binding without alteration in receptor number

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photoaffinity labeling of the insulin receptor in H4 hepatoma cells: lack of cellular receptor processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-stimulated tyrosine phosphorylation of the insulin receptor in detergent extracts of human placental membranes. Comparison to epidermal growth factor-stimulated phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photoaffinity labeling of insulin receptors in viable cultured human lymphocytes. Demonstration of receptor shedding and degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct demonstration of insulin receptor internalization. A quantitative electron microscopic study of covalently bound 125I-photoreactive insulin incubated with isolated hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin receptor binding to fat and blood cells and insulin action in fat cells from insulin-dependent diabetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship between the insulin-binding capacity of fat cells and the cellular response to insulin. Studies with intact and trypsin-treated fat cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-dependent regulation of the insulin-sensitivity of adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI111160

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q35208007&oldid=1987574878"