(Q35207580)

7 August 2017

title

A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest (English)

1 reference

7 August 2017

G F Claassen

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7 August 2017

S R Hann

series ordinal

1 reference

7 August 2017

language of work or name

English

0 references

publication date

1 August 2000

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Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

published in

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7 August 2017

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7 August 2017

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7 August 2017

page(s)

9498-9503

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Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

7 August 2017

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13 July 2018

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c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points

13 July 2018

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13 July 2018

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Overexpression of c-Myc inhibits p21WAF1/CIP1 expression and induces S-phase entry in 12-O-tetradecanoylphorbol-13-acetate (TPA)-sensitive human cancer cells

13 July 2018

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c-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets

13 July 2018

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13 July 2018

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13 July 2018

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TGF-beta signal transduction

13 July 2018

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The molecular role of Myc in growth and transformation: recent discoveries lead to new insights

13 July 2018

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Histone deacetylase inhibitor activates the WAF1/Cip1 gene promoter through the Sp1 sites

13 July 2018

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Mechanism and function of signaling by the TGF beta superfamily.

13 July 2018

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Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPbeta

13 July 2018

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Phenotypes of c-Myc-deficient rat fibroblasts isolated by targeted homologous recombination.

13 July 2018

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Transforming growth factor‐β: The breaking open of a black box

13 July 2018

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13 July 2018

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Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

13 July 2018

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Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

13 July 2018

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A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

13 July 2018

1 reference

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The viral oncoprotein E1A blocks transforming growth factor beta-mediated induction of p21/WAF1/Cip1 and p15/INK4B.

13 July 2018

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Cyclin-dependent kinase regulation during G1 phase and cell cycle regulation by TGF-beta

13 July 2018

1 reference

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Identification of downstream-initiated c-Myc proteins which are dominant-negative inhibitors of transactivation by full-length c-Myc proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

c-Myc inactivation by mutant Max alters growth and morphology of NCI-H-630 colon cancer cells

13 July 2018

1 reference

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Proteins of the Myc network: essential regulators of cell growth and differentiation.

13 July 2018

1 reference

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Direct role for Myc in transcription initiation mediated by interactions with TFII-I

13 July 2018

1 reference

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Intracellular association of the protein product of the c-myc oncogene with the TATA-binding protein

13 July 2018

1 reference

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WAF1, a potential mediator of p53 tumor suppression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Induction of WAF1/CIP1 by a p53-independent pathway

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

The alternatively initiated c-Myc proteins differentially regulate transcription through a noncanonical DNA-binding site

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

p21-containing cyclin kinases exist in both active and inactive states

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

TATA-binding protein and the retinoblastoma gene product bind to overlapping epitopes on c-Myc and adenovirus E1A protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Inhibition of cyclin-dependent kinases by p21

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

p21 Is a Component of Active Cell Cycle Kinases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Proteins encoded by v-myc and c-myc oncogenes: Identification and localization in acute leukemia virus transformants and bursal lymphoma cell lines

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor beta

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Enhanced translation and increased turnover of c-myc proteins occur during differentiation of murine erythroleukemia cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

The MYC protein activates transcription of the alpha-prothymosin gene.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Loss of transforming growth factor beta 1 (TGF-beta 1)-induced growth arrest and p34cdc2 regulation in ras-transfected epithelial cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Modifications of cell cycle controlling nuclear proteins by transforming growth factor beta in the HaCaT keratinocyte cell line.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Structure and expression of the human gene for the matrix metalloproteinase matrilysin.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Regulation of cell cycle duration by c-myc levels.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16893

Myc represses the growth arrest gene gadd45

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.150006697

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.150006697

Sensitivity to transforming growth factor beta 1-induced growth arrest is common in human squamous cell carcinoma cell lines: c-MYC down-regulation and p21waf1 induction are important early events

21 January 2018

1 reference

12 December 2020

The CDK inhibitor p21WAF1/Cip1 is induced through a p300-dependent mechanism during NGF-mediated neuronal differentiation of PC12 cells

1 reference

12 December 2020

Transforming growth factor beta and cell cycle regulation

1 reference

12 December 2020

Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.150006697

1 reference

7 August 2017

0 references

1 reference

7 August 2017

1 reference