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Fatty acid metabolism and insulin secretion in pancreatic beta cells

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Europe PubMed Central

PubMed publication ID

7 August 2017

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Europe PubMed Central

Fatty acid metabolism and insulin secretion in pancreatic beta cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

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1 reference

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author name string

Yaney GC

1

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Corkey BE

2

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

language of work or name

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based on heuristic

inferred from title

publication date

12 September 2003

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Europe PubMed Central

PubMed publication ID

7 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

46

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

1297-1312

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

The antidiabetic beta 3-adrenoceptor agonist BRL 26830A works by release of endogenous insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromaffin cell cortical actin network dynamics control the size of the release-ready vesicle pool and the initial rate of exocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of 25-kDa synaptosome-associated protein. Possible involvement in protein kinase C-mediated regulation of neurotransmitter release

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid-induced beta cell hypersensitivity to glucose. Increased phosphofructokinase activity and lowered glucose-6-phosphate content

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C in beta-cells: expression of multiple isoforms and involvement in cholinergic stimulation of insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and subcellular characterization of protein kinase-C isoforms in insulinoma beta-cells and whole islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the ATP-sensitive K+ channel by long chain acyl-CoA. A role in modulation of pancreatic beta-cell glucose sensitivity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acyl CoA regulation of metabolism and signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The stimulus-secretion coupling of glucose-induced insulin release: fuel metabolism in islets deprived of exogenous nutrient

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting of SNAP-25 to membranes is mediated by its association with the target SNARE syntaxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of protein kinase C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C modulates the insulin secretory process by maintaining a proper function of the beta-cell voltage-activated Ca2+ channels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose stimulation of insulin secretion in islets of fed and starved rats and its dependence on lipid metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New insights into the mitochondrial carnitine palmitoyltransferase enzyme system

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-induced translocation of protein kinase C in rat pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obesity and insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of a novel alpha 1-subunit of the voltage-dependent calcium channel from the beta-cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+/calmodulin and cyclic 3,5' adenosine monophosphate control movement of secretory granules through protein phosphorylation/dephosphorylation in the pancreatic beta-cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shared biochemical properties of glucotoxicity and lipotoxicity in islets decrease citrate synthase activity and increase phosphofructokinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linked oscillations of free Ca2+ and the ATP/ADP ratio in permeabilized RINm5F insulinoma cells supplemented with a glycolyzing cell-free muscle extract

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible Ca2+-dependent translocation of protein kinase C and glucose-induced insulin release.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acyl-CoA esters modulate intracellular Ca2+ handling by permeabilized clonal pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diacylglycerol synthesis de novo from glucose by pancreatic islets isolated from rats and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphofructokinase isozymes in pancreatic islets and clonal beta-cells (INS-1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acyl-coenzyme A is required for budding of transport vesicles from Golgi cisternae

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Syntaxin 1 interacts with the L(D) subtype of voltage-gated Ca(2+) channels in pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential Role of Acetyl-CoA Carboxylase in the Glucose-Induced Insulin Secretion in a Pancreatic β-Cell Line

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic exposure to TPA depletes PKC alpha and augments Ca-dependent insulin secretion from cultured rat islets.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two different spatiotemporal patterns for Ca2+ oscillations in pancreatic acinar cells: evidence of a role for protein kinase C in Ins(1,4,5)P3-mediated Ca2+ signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty Acids Decrease IDX-1 Expression in Rat Pancreatic Islets and Reduce GLUT2, Glucokinase, Insulin, and Somatostatin Levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atypical β-adrenoceptor on brown adipocytes as target for anti-obesity drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]-amino] propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent beta-adrenergic agonist virtually specific for beta 3 receptors. A promising antidiabetic and antiobesity agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular machinery mediating vesicle budding, docking and fusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretagogue-induced [Ca2+]i changes in single rat pancreatic islets and correlation with simultaneously measured insulin release

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple palmitoylation of synaptotagmin and the t-SNARE SNAP-25

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of the stimulation of insulin release by saturated fatty acids. A study of palmitate effects in mouse beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ICI D7114: a novel selective adrenoceptor agonist of brown fat and thermogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific inhibition of glucokinase by long chain acyl coenzymes A below the critical micelle concentration

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerulenin, an inhibitor of protein acylation, selectively attenuates nutrient stimulation of insulin release: a study in rat pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C: a paradigm for regulation of protein function by two membrane-targeting modules

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of phospholipid-derived mediators including arachidonic acid, its metabolites, and inositoltrisphosphate and of intracellular Ca2+ in glucose-induced insulin secretion by pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long chain coenzyme A esters activate the pore-forming subunit (Kir6. 2) of the ATP-regulated potassium channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane targeting of L-type calcium channels. Role of palmitoylation in the subcellular localization of the beta2a subunit.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of islet protein kinase C translocation by palmitate requires metabolism of the fatty acid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of L- and non-L-type calcium channels to voltage-gated calcium current and glucose-dependent insulin secretion in HIT-T15 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hexamminecobalt(III) chloride inhibits glucose-induced insulin secretion at the exocytotic process

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the readily releasable vesicle pool by protein kinase C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposite effects of short- and long-term fatty acid infusion on insulin secretion in healthy subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of ketone bodies on insulin release and islet-cell metabolism in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute effects of fatty acids on insulin secretion from rat and human islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SNAP-25 Palmitoylation and Plasma Membrane Targeting Require a Functional Secretory Pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of CL-316,243, a thermogenic beta 3-agonist, on energy balance and brown and white adipose tissues in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C isotypes and signaling in neutrophils. Differential substrate specificities of a translocatable calcium- and phospholipid-dependent beta-protein kinase C and a phospholipid-dependent protein kinase which is inhibited by long chain f

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the docked granule pool responsible for the first phase of glucose-stimulated insulin secretion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the hormone-sensitive lipase in adipose tissue by long-chain fatty acyl coenzyme A

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pleiotypic mechanisms of cellular responses to biologically active lysophospholipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of insulin secretion by phospholipase C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A fatty acid- dependent step is critically important for both glucose- and non-glucose-stimulated insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coupling factors in nutrient-induced insulin release

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of the role of group VI phospholipase A2 in fatty acid incorporation, phospholipid remodeling, lysophosphatidylcholine generation, and secretagogue-induced arachidonic acid release in pancreatic islets and insulinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low Density Lipoprotein Binding and Uptake by Human and Rat Isletβ Cells*

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of the alpha 1 subunit of a voltage-dependent calcium channel expressed in pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal sequence of metabolic and ionic events in glucose-stimulated clonal pancreatic beta-cells (HIT).

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose and carbachol generate 1,2-diacylglycerols by different mechanisms in pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The expression of hormone-sensitive lipase in clonal beta-cells and rat islets is induced by long-term exposure to high glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

β3-Adrenergic Receptors on White and Brown Adipocytes Mediate β3-Selective Agonist-induced Effects on Energy Expenditure, Insulin Secretion, and Food Intake

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunocytochemical localization of alpha-protein kinase C in rat pancreatic beta-cells during glucose-induced insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Starvation-induced changes of palmitate metabolism and insulin secretion in isolated rat islets stimulated by glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptobrevin 2 is palmitoylated in synaptic vesicles prepared from adult, but not from embryonic brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ambient plasma free fatty acid concentrations in noninsulin-dependent diabetes mellitus: evidence for insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repetitive mitochondrial Ca 2+ signals synchronize with cytosolic Ca 2+ oscillations in the pancreatic beta-cell line, MIN6

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct effects of fatty acids on translocation of gamma- and epsilon-subspecies of protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single islet beta-cell stimulation by nutrients: relationship between pyridine nucleotides, cytosolic Ca2+ and secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Adenylate cyclase-cyclic AMP system in islets of langerhans and its role in the control of insulin release

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How are free fatty acids transported in membranes? Is it by proteins or by free diffusion through the lipids?

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Banting lecture 1990. Beta-cells in type II diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrospray ionization mass spectrometric analyses of phospholipids from INS-1 insulinoma cells: comparison to pancreatic islets and effects of fatty acid supplementation on phospholipid composition and insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global and societal implications of the diabetes epidemic

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of acyl-coenzyme A with phosphatidylcholine bilayers and serum albumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calmodulin and protein kinase C increase Ca(2+)-stimulated secretion by modulating membrane-attached exocytic machinery

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose and insulin stimulate heparin-releasable lipoprotein lipase activity in mouse islets and INS-1 cells. A potential link between insulin resistance and beta-cell dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cardiac L-type calcium channels by protein kinase C phosphorylation of two sites in the N-terminal domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Cell Physiology of Biphasic Insulin Secretion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of insulin secretion by infusion of free fatty acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

More direct evidence for a malonyl-CoA-carnitine palmitoyltransferase I interaction as a key event in pancreatic beta-cell signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimates of glycolysis, pyruvate (de)carboxylation, pentose phosphate pathway, and methyl succinate metabolism in incapacitated pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acylation promotes fusion of transport vesicles with Golgi cisternae

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction mechanisms in nutrient-induced insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oscillations in cytosolic free Ca2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolism of lipids in mouse pancreatic islets. The biosynthesis of triacylglycerols and phospholipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-induced metabolic oscillations parallel those of Ca(2+) and insulin release in clonal insulin-secreting cells. A multiwell approach to oscillatory cell behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucagon-like peptide 1 stimulates lipolysis in clonal pancreatic beta-cells (HIT).

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the beta 3-adrenergic receptor gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of Munc-18/n-Sec1/rbSec1 by protein kinase C: its implication in regulating the interaction of Munc-18/n-Sec1/rbSec1 with syntaxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma Triglyceride and Fatty Acid Metabolism in Diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a Unique Long Chain Acyl-CoA Ester Binding Site on the ATP-regulated Potassium Channel in Mouse Pancreatic Beta Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are Metabolic Oscillations Responsible for Normal Oscillatory Insulin Secretion?

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Palmitate dependence of insulin secretion, "de novo" phospholipid synthesis and 45Ca2+-turnover in glucose stimulated rat islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of fatty acids on insulin release: role of chain length and degree of unsaturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antilipolytic agent 3,5-dimethylpyrazole inhibits insulin release in response to both nutrient secretagogues and cyclic adenosine monophosphate agonists in isolated rat islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subunit structure of dihydropyridine-sensitive calcium channels from skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

What if Minkowski had been ageusic? An alternative angle on diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of steady-state free Ca2+ levels by the ATP/ADP ratio and orthophosphate in permeabilized RINm5F insulinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective regulation of protein kinase C isoenzymes by oleic acid in human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential mechanisms of glucose and palmitate in augmentation of insulin secretion in mouse pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the interaction of palmitoyl coenzyme A with the adenine nucleotide translocase

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin release in pancreatic islets by a glycolytic and a Krebs cycle intermediate: contrasting patterns of glyceraldehyde phosphate and succinate

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal patterns of changes in ATP/ADP ratio, glucose 6-phosphate and cytoplasmic free Ca2+ in glucose-stimulated pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATP-sensitive K channel modulation by products of PLA2 action in the insulin-secreting HIT cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane localization and biological activity of SNAP-25 cysteine mutants in insulin-secreting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergism of protein kinase A, protein kinase C, and myosin light-chain kinase in the secretory cascade of the pancreatic beta-cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acids rapidly induce the carnitine palmitoyltransferase I gene in the pancreatic beta-cell line INS-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cysteine residues of SNAP-25 are required for SNARE disassembly and exocytosis, but not for membrane targeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of ATP-regulated K+ channels precedes depolarization-induced increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells).

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of insulin release by phospholipase D. A potential role for endogenous phosphatidic acid in pancreatic islet function

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-chain acyl CoA regulation of protein kinase C and fatty acid potentiation of glucose-stimulated insulin secretion in clonal beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C acylation by palmitoyl coenzyme A facilitates its translocation to membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different requirements for protein kinase C activation and Ca2+-independent insulin secretion in response to guanine nucleotides. Endogenously generated diacylglycerol requires elevated Ca2+ for kinase C insertion into membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucagon-like peptide 1 and fatty acids amplify pulsatile insulin secretion from perifused rat islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for hormone-sensitive lipase in glucose-stimulated insulin secretion: a study in hormone-sensitive lipase-deficient mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fuel concept for insulin release: regulation of glucose phosphorylation in pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of Glyconeogenesis in Pancreatic Islets: Expression of Gluconeogenic Enzyme Genes in Islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pulsatile insulin secretion: detection, regulation, and role in diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C activity affects glucose-induced oscillations in cytoplasmic free Ca2+ in the pancreatic B-cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal and quantitative correlations between insulin secretion and stably elevated or oscillatory cytoplasmic Ca2+ in mouse pancreatic beta-cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular diversity and functional characterization of voltage-dependent calcium channels (CACN4) expressed in pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Palmitate and myristate selectively mimic the effect of glucose in augmenting insulin release in the absence of extracellular Ca2+

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A key role for a 145-kDa cytosolic protein in the stimulation of Ca(2+)-dependent secretion by protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolism of lipids in mouse pancreatic islets. The oxidation of fatty acids and ketone bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATP-sensitive K+ channel-independent glucose action in rat pancreatic beta-cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of glucose-induced insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beneficial effect of diazoxide in obese hyperinsulinemic adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM?

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms regulating hormone-sensitive lipase and lipolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acids and beta-cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C enhances exocytosis from chromaffin cells by increasing the size of the readily releasable pool of secretory granules

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

K(ATP) channels: linker between phospholipid metabolism and excitability

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The voltage sensitive Lc-type Ca2+ channel is functionally coupled to the exocytotic machinery

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of protein kinase C isoenzymes in fatty acid stimulation of insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of pancreatic beta-cell mitochondrial metabolism: influence of Ca2+, substrate and ADP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of acyl-coenzyme A esters in biological samples

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High saturated fat and low starch and fibre are associated with hyperinsulinaemia in a non-diabetic population: the San Luis Valley Diabetes Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormalities of insulin pulsatility and glucose oscillations during meals in obese noninsulin-dependent diabetic patients: effects of weight reduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C and calcium regulation of adenylyl cyclase in isolated rat pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of insulin secretion by phorbol esters is mediated by PKC-alpha and nPKC isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translocation inhibitors define specificity of protein kinase C isoenzymes in pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Carbohydrates on the Oxygen Consumption of Isolated Pancreatic Islets of Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose stimulation of insulin release in the absence of extracellular Ca2+ and in the absence of any increase in intracellular Ca2+ in rat pancreatic islets.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of N- and L-type calcium channel currents by protein kinase C in frog sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular diversity and functional characterization of voltage-dependent calcium channels (CACN4) expressed in pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13680127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-003-1207-4

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

ResearchGate publication ID

0 references

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