(Q35128243)

6 August 2017

title

Organization of the integrin LFA-1 in nanoclusters regulates its activity (English)

1 reference

6 August 2017

Frank N van Leeuwen

0 references

Jack A Fransen

0 references

Alessandra Cambi

0 references

Ruurd Torensma

0 references

Carl G Figdor

0 references

Ben Joosten

1 reference

6 August 2017

Marjolein Koopman

1 reference

6 August 2017

Frank de Lange

1 reference

6 August 2017

Inge Beeren

1 reference

6 August 2017

Maria Garcia-Parajó

1 reference

6 August 2017

publication date

19 July 2006

1 reference

Molecular Biology of the Cell

6 August 2017

published in

1 reference

6 August 2017

1 reference

6 August 2017

1 reference

6 August 2017

page(s)

4270-4281

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Molecular mechanisms that set the stage for DC-T cell engagement.

6 August 2017

cites work

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RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

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Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation

13 July 2018

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A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

13 July 2018

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Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation

13 July 2018

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CD18 activation epitopes induced by leukocyte activation

13 July 2018

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Locking in alternate conformations of the integrin alphaLbeta2 I domain with disulfide bonds reveals functional relationships among integrin domains

13 July 2018

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An isolated, surface-expressed I domain of the integrin alphaLbeta2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond.

13 July 2018

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Integrin cytoplasmic domain-binding proteins

13 July 2018

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Cytohesin-1 regulates beta-2 integrin-mediated adhesion through both ARF-GEF function and interaction with LFA-1

13 July 2018

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Cholesterol-dependent clustering of IL-2Ralpha and its colocalization with HLA and CD48 on T lymphoma cells suggest their functional association with lipid rafts.

13 July 2018

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DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

13 July 2018

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Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses

13 July 2018

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Overexpression of CD82 on human T cells enhances LFA-1 / ICAM-1-mediated cell-cell adhesion: functional association between CD82 and LFA-1 in T cell activation

13 July 2018

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Integrin leukocyte function-associated antigen-1-mediated cell binding can be activated by clustering of membrane rafts

13 July 2018

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The actin cytoskeleton regulates LFA-1 ligand binding through avidity rather than affinity changes

13 July 2018

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The immunological synapse: a molecular machine controlling T cell activation

13 July 2018

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Cytoskeletal interactions with the leukocyte integrin beta2 cytoplasmic tail. Activation-dependent regulation of associations with talin and alpha-actinin

13 July 2018

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Three-dimensional segregation of supramolecular activation clusters in T cells

13 July 2018

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Dendritic cells and the control of immunity

13 July 2018

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Are changes in integrin affinity and conformation overemphasized?

13 July 2018

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13 July 2018

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13 July 2018

Ins and outs of LFA-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635357

Extracellular Ca2+ modulates leukocyte function-associated antigen-1 cell surface distribution on T lymphocytes and consequently affects cell adhesion

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635357

LFA-1 and other accessory molecules functioning in adhesions of T and B lymphocytes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635357

The specific interaction of helper T cells and antigen-presenting B cells. IV. Membrane and cytoskeletal reorganizations in the bound T cell as a function of antigen dose

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635357

Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635357

Regulated expression of Mg2+ binding epitope on leukocyte integrin alpha subunits

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635357

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635357

Adhesion receptors of the immune system

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635357

Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635357

Activation of LFA-1 through a Ca2(+)-dependent epitope stimulates lymphocyte adhesion

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635357

Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635357

Leukocyte function-associated antigen 1-mediated adhesion stability is dynamically regulated through affinity and valency during bond formation with intercellular adhesion molecule-1.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635357

Membrane cholesterol regulates LFA-1 function and lipid raft heterogeneity

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635357

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

27 September 2018

1 reference

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The involvement of lipid rafts in the regulation of integrin function

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1 reference

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Anti-CD81 activates LFA-1 on T cells and promotes T cell-B cell collaboration.

27 September 2018

1 reference

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DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking.

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1 reference

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A monoclonal antibody (NKI-L16) directed against a unique epitope on the alpha-chain of human leukocyte function-associated antigen 1 induces homotypic cell-cell interactions

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1 reference

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Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking

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12 December 2020

High frequency of adhesion defects in B-lineage acute lymphoblastic leukemia

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Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)

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Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes

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Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability

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Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines

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Identifiers

DOI

10.1091/MBC.E05-12-1098

1 reference

6 August 2017

1 reference

6 August 2017

1 reference