(Q35191607)

7 August 2017

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title

Not just for housekeeping: protein initiation and elongation factors in cell growth and tumorigenesis (English)

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7 August 2017

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Sarah Thornton

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7 August 2017

Nisha Anand

series ordinal

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7 August 2017

Dan Purcell

series ordinal

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7 August 2017

Jonathan Lee

series ordinal

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7 August 2017

publication date

1 August 2003

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Journal of Molecular Medicine

7 August 2017

published in

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7 August 2017

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7 August 2017

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7 August 2017

page(s)

536-548

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Changes in activity and amount of active elongation factor 1 alpha in aging and immortal human fibroblast cultures.

7 August 2017

cites work

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12 December 2020

Expression of the translation initiation factor eIF4E in the polyp-cancer sequence in the colon

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12 December 2020

'Wasted', a new mutant of the mouse with abnormalities characteristic to ataxia telangiectasia

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12 December 2020

Overexpression of eukaryotic initiation factor 4E (eIF4E) in breast carcinoma

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12 December 2020

Elongation factor-1alpha stabilizes microtubules in a calcium/calmodulin-dependent manner

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12 December 2020

The regulation of protein synthesis in animal cells by serum factors

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12 December 2020

The effects of enhanced expression of elongation factor EF-1 alpha on lifespan in Drosophila melanogaster. IV. A summary of three experiments

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12 December 2020

Replicative senescence of human fibroblast-like cells in culture

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12 December 2020

Elongation factor 1 gamma mRNA expression in oesophageal carcinoma

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12 December 2020

Genomics, gene expression and DNA arrays

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12 December 2020

The mitotic apparatus-associated 51-kDa protein from sea urchin eggs is a GTP-binding protein and is immunologically related to yeast polypeptide elongation factor 1 alpha

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12 December 2020

Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic.

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12 December 2020

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12 December 2020

Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays

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12 December 2020

Comparative genomic hybridization analysis detects frequent, often high-level, overrepresentation of DNA sequences at 3q, 5p, 7p, and 8q in human non-small cell lung carcinomas

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12 December 2020

From patterns to pathways: gene expression data analysis comes of age.

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12 December 2020

Longitudinal assessment of immunologic abnormalities of mice with the autosomal recessive mutation, "wasted".

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12 December 2020

Does the ribosome translate cancer?

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12 December 2020

Elongation factor 1α, translation and the cytoskeleton

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12 December 2020

Pattern of amplification and overexpression of the eukaryotic initiation factor 4E gene in solid tumor

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12 December 2020

Phosphorylation of elongation factor 1 (EF-1) and valyl-tRNA synthetase by protein kinase C and stimulation of EF-1 activity

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12 December 2020

Oncogenic kinase signalling

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12 December 2020

Decline in synthesis of elongation factor one (EF-1) precedes the decreased synthesis of total protein in aging Drosophila melanogaster.

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12 December 2020

Transcription factors as targets for cancer therapy

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12 December 2020

Expression of eukaryotic translation initiation factors 4E and 2alpha is increased frequently in bronchioloalveolar but not in squamous cell carcinomas of the lung

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12 December 2020

Stimulation of translation in 3T3-L1 cells in response to insulin and phorbol ester is directly correlated with increased phosphate labelling of initiation factor (eIF-) 4F and ribosomal protein S6.

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12 December 2020

Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer

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12 December 2020

Control of cell growth by c-Myc in the absence of cell division

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12 December 2020

The overexpression of elongation factor 1 gamma mRNA in gastric carcinoma

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12 December 2020

Modelling the molecular circuitry of cancer

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12 December 2020

Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer

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12 December 2020

Assignment of human elongation factor 1alpha genes: EEF1A maps to chromosome 6q14 and EEF1A2 to 20q13.3

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12 December 2020

Genetic aberrations detected by comparative genomic hybridization in ovarian clear cell adenocarcinomas.

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12 December 2020

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

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12 December 2020

Molecular portraits of human breast tumours

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12 December 2020

Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression

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12 December 2020

Discordant protein and mRNA expression in lung adenocarcinomas

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12 December 2020

Analysing gene expression data from DNA microarrays to identify candidate genes

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12 December 2020

Altered cellular responses by varying expression of a ribosomal protein gene: sequential coordination of enhancement and suppression of ribosomal protein S3a gene expression induces apoptosis

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12 December 2020

Microtubule severing by elongation factor 1 alpha

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12 December 2020

Protein synthesis elongation factor EF-1 alpha expression and longevity in Drosophila melanogaster

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12 December 2020

Progression of eIF4e gene amplification and overexpression in benign and malignant tumors of the head and neck.

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12 December 2020

Elongation factor-1 alpha gene determines susceptibility to transformation

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12 December 2020

Differential screening of a human pancreatic adenocarcinoma lambda gt11 expression library has identified increased transcription of elongation factor EF-1 alpha in tumour cells

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12 December 2020

Peptide elongation factor eEF1A-2/S1 expression in cultured differentiated myotubes and its protective effect against caspase-3-mediated apoptosis

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12 December 2020

Gains and losses of DNA sequences in childhood brain tumors analyzed by comparative genomic hybridization.

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12 December 2020

Biological characterization of various forms of elongation factor 1 from rabbit reticulocytes

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12 December 2020

Regulation of peptide-chain elongation in mammalian cells

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12 December 2020

Amplification of chromosomal region 20q13 in invasive breast cancer: prognostic implications

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12 December 2020

Discovery of over-expressed genes and genetic alterations in breast cancer cells using a combination of suppression subtractive hybridization, multiplex FISH and comparative genomic hybridization

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12 December 2020

Genetic aberrations detected by comparative genomic hybridization predict outcome in node-negative breast cancer

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12 December 2020

A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders

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12 December 2020

Tissue-dependent variation in the expression of elongation factor-1 alpha isoforms: isolation and characterisation of a cDNA encoding a novel variant of human elongation-factor 1 alpha

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12 December 2020

Correlation of p53 and the proto-oncogene eIF4E in larynx cancers: prognostic implications

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12 December 2020

Deletion of chromosomal region 6q14-16 in prostate cancer

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12 December 2020

Understanding inner ear development with gene expression profiling.

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12 December 2020

Molecular and functional profiling of memory CD8 T cell differentiation.

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12 December 2020

Identification of the human prostatic carcinoma oncogene PTI-1 by rapid expression cloning and differential RNA display

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12 December 2020

Specific disappearance of translatable messenger RNA for elongation factor one in aging Drosophila melanogaster

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12 December 2020

Phosphorylation of elongation factor 1 (EF-1) by protein kinase C stimulates GDP/GTP-exchange activity

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12 December 2020

Coordination of growth with cell division in the yeast Saccharomyces cerevisiae

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12 December 2020

Increased copy number at 20q13 in breast cancer: defining the critical region and exclusion of candidate genes

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12 December 2020

F-actin sequesters elongation factor 1alpha from interaction with aminoacyl-tRNA in a pH-dependent reaction

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12 December 2020

The effect of F-actin on the binding and hydrolysis of guanine nucleotide by Dictyostelium elongation factor 1A

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12 December 2020

Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction

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12 December 2020

Ras mediates translation initiation factor 4E-induced malignant transformation

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12 December 2020

Phosphorylation of valyl-tRNA synthetase and elongation factor 1 in response to phorbol esters is associated with stimulation of both activities

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12 December 2020

Noncoordinated expression of S6, S11, and S14 ribosomal protein genes in leukemic blast cells

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12 December 2020

Differentially expressed genes identified in human melanoma cell lines with different metastatic behaviour using high density oligonucleotide arrays

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12 December 2020

The economics of ribosome biosynthesis in yeast

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12 December 2020

An analysis of vertebrate mRNA sequences: intimations of translational control

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12 December 2020

Identification of genes differentially expressed in association with acquired cisplatin resistance

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12 December 2020

Identification of differentially expressed genes associated with androgen-independent growth of prostate cancer

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12 December 2020

Isolation of gene associated with high metastatic potential in rat mammary adenocarcinomas

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12 December 2020

Genetic changes in clinically organ-confined prostate cancer by comparative genomic hybridization

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12 December 2020

Tissue-specific expression in mammalian brain, heart, and muscle of S1, a member of the elongation factor-1 alpha gene family.

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12 December 2020

Bundling of actin filaments by elongation factor 1 alpha inhibits polymerization at filament ends

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12 December 2020

Phosphorylation of Elongation Factor 1 and Ribosomal Protein S6 by Multipotential S6 Kinase and Insulin Stimulation of Translational Elongation

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12 December 2020

Translation factors as effectors of cell growth and tumorigenesis

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12 December 2020

The lethal mutation of the mouse wasted (wst) is a deletion that abolishes expression of a tissue-specific isoform of translation elongation factor 1alpha, encoded by the Eef1a2 gene

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12 December 2020

Prospective study of eukaryotic initiation factor 4E protein elevation and breast cancer outcome

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12 December 2020

Effect of age on peptide chain initiation and elongation in preparations from brain, liver, kidney and skeletal muscle of the C57B1/6J mouse

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12 December 2020

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12 December 2020

Independent amplification and frequent co-amplification of three nonsyntenic regions on the long arm of chromosome 20 in human breast cancer

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12 December 2020

20q13 and cyclin D1 in ovarian carcinomas. Analysis by fluorescence in situ hybridization

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12 December 2020

Oncogenic potential of mouse translation elongation factor-1 delta, a novel cadmium-responsive proto-oncogene

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12 December 2020

Antisense inhibition of the PTI-1 oncogene reverses cancer phenotypes

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12 December 2020

Fruit flies with additional expression of the elongation factor EF-1 alpha live longer

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12 December 2020

Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

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12 December 2020

ATM: from gene to function

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12 December 2020

Detection of eIF4E gene amplification in breast cancer by competitive PCR.

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12 December 2020

Enhanced expression of translation factor mRNAs in hepatocellular carcinoma.

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12 December 2020

Elongation factor-1 alpha is an overexpressed actin binding protein in metastatic rat mammary adenocarcinoma

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12 December 2020

Glutathione-associated enzymes in the human cell lines of the National Cancer Institute Drug Screening Program

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12 December 2020

Correlation between protein and mRNA abundance in yeast

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12 December 2020

Identification of an actin-binding protein from Dictyostelium as elongation factor 1a.

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12 December 2020

Gene expression profiles in normal and cancer cells

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12 December 2020

Regulation of protein synthesis by insulin

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12 December 2020

Characterization of immunologic and neuropathologic abnormalities in wasted mice

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12 December 2020

Translational control in mammalian cells

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12 December 2020

Purification and characterization of a phosphatidylinositol 4-kinase activator in carrot cells

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12 December 2020

Mutations in elongation factor 1beta, a guanine nucleotide exchange factor, enhance translational fidelity

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12 December 2020

Compartmentalization and actin binding properties of ABP-50: the elongation factor-1 alpha of Dictyostelium

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12 December 2020

The wst gene regulates multiple forms of thymocyte apoptosis

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12 December 2020

Elongation factor-1 alpha is a selective regulator of growth factor withdrawal and ER stress-induced apoptosis

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12 December 2020

Radiation sensitivity of T-lymphocytes from immunodeficient "wasted" mice

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12 December 2020

A sampling of the yeast proteome

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12 December 2020

Two novel tumor suppressor gene loci on chromosome 6q and 15q in human osteosarcoma identified through comparative study of allelic imbalances in mouse and man

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12 December 2020

10.1007/S00109-003-0461-8

Identifiers

DOI

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7 August 2017

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