(Q35144535)

6 August 2017

title

Catechol metabolites of endogenous estrogens induce redox cycling and generate reactive oxygen species in breast epithelial cells (English)

1 reference

6 August 2017

main subject

reactive oxygen species

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1 reference

Karma C Fussell

1 reference

6 August 2017

Ronald G Udasin

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6 August 2017

Peter J S Smith

1 reference

6 August 2017

Michael A Gallo

1 reference

6 August 2017

Jeffrey D Laskin

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6 August 2017

language of work or name

English

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publication date

10 June 2011

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6 August 2017

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

1285-1293

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Redox cycling and increased oxygen utilization contribute to diquat-induced oxidative stress and cytotoxicity in Chinese hamster ovary cells overexpressing NADPH-cytochrome P450 reductase.

6 August 2017

cites work

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Application of the Amplex red/horseradish peroxidase assay to measure hydrogen peroxide generation by recombinant microsomal enzymes

13 July 2018

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Profiling endogenous serum estrogen and estrogen-glucuronides by liquid chromatography-tandem mass spectrometry.

13 July 2018

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17-Beta-estradiol inhibits transforming growth factor-beta signaling and function in breast cancer cells via activation of extracellular signal-regulated kinase through the G protein-coupled receptor 30.

13 July 2018

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Nuclear and extranuclear pathway inputs in the regulation of global gene expression by estrogen receptors

13 July 2018

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Role of cytochrome P450 reductase in nitrofurantoin-induced redox cycling and cytotoxicity.

13 July 2018

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Potential mechanisms of estrogen quinone carcinogenesis

13 July 2018

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Estrogen-induced generation of reactive oxygen and nitrogen species, gene damage, and estrogen-dependent cancers

13 July 2018

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Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention

13 July 2018

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Estrogen carcinogenesis in breast cancer

13 July 2018

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A transmembrane intracellular estrogen receptor mediates rapid cell signaling

13 July 2018

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Interactions of mammalian cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b(5) enzymes

13 July 2018

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Quinoids formed from estrogens and antiestrogens

13 July 2018

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Estrogen and its metabolites are carcinogenic agents in human breast epithelial cells.

13 July 2018

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Metabolism and DNA binding studies of 4-hydroxyestradiol and estradiol-3,4-quinone in vitro and in female ACI rat mammary gland in vivo

13 July 2018

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The estrogen receptor: a model for molecular medicine.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Quinoids, quinoid radicals, and phenoxyl radicals formed from estrogens and antiestrogens

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial

13 July 2018

1 reference

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Evidence that a metabolite of equine estrogens, 4-hydroxyequilenin, induces cellular transformation in vitro

13 July 2018

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Role of DNA adducts in hormonal carcinogenesis

13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Estrogens as endogenous genotoxic agents--DNA adducts and mutations

13 July 2018

1 reference

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Role of quinones in toxicology.

13 July 2018

1 reference

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Oxygen and nitrogen are pro-carcinogens. Damage to DNA by reactive oxygen, chlorine and nitrogen species: measurement, mechanism and the effects of nutrition

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast cancer. Collaborative Group on Hormonal Factors in Breast Cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Lipid peroxidation-induced putative malondialdehyde-DNA adducts in human breast tissues.

13 July 2018

1 reference

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Breast tumor cell lines from pleural effusions

13 July 2018

1 reference

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Resolution of the cytochrome P-450-containing omega-hydroxylation system of liver microsomes into three components

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

A human cell line from a pleural effusion derived from a breast carcinoma

13 July 2018

1 reference

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Protective effects of progesterone and tamoxifen in estrogen-induced mammary carcinogenesis in ovariectomized W/Fu rats.

13 July 2018

1 reference

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Cytochrome P-450-mediated redox cycling of estrogens

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Estrogen-induced endogenous DNA adduction: possible mechanism of hormonal cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

13 July 2018

1 reference

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Increased cell division as a cause of human cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

The effects of caffeic acid and its related catechols on hydroxyl radical formation by 3-hydroxyanthranilic acid, ferric chloride, and hydrogen peroxide.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Effects of 17 beta-estradiol metabolites on cell cycle events in MCF-7 cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Spontaneous and estrogen-produced tumors in Nb rats and their behavior after transplantation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Paraquat increases cyanide-insensitive respiration in murine lung epithelial cells by activating an NAD(P)H:paraquat oxidoreductase: identification of the enzyme as thioredoxin reductase.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Oxidative changes in the DNA of stroma and epithelium from the female breast: potential implications for breast cancer

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Characterization of hydroxyl radical formation by microsomal enzymes using a water-soluble trap, terephthalate

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Detection of estrogen DNA-adducts in human breast tumor tissue and healthy tissue by combined nano LC-nano ES tandem mass spectrometry

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Endogenous sex hormones and breast cancer in postmenopausal women: reanalysis of nine prospective studies

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Real-time detection of reactive oxygen intermediates from single microglial cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

The effects of catechol-O-methyltransferase inhibition on estrogen metabolite and oxidative DNA damage levels in estradiol-treated MCF-7 cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Role of human cytochrome P450 1A1, 1A2, 1B1, and 3A4 in the 2-, 4-, and 16alpha-hydroxylation of 17beta-estradiol

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Metabolism of equilenin in MCF-7 and MDA-MB-231 human breast cancer cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Role of quinoids in estrogen carcinogenesis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Bioreductive activation of catechol estrogen-ortho-quinones: aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

Catecholestrogens are MCF-7 cell estrogen receptor agonists

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

The action of paraquat and diquat on the respiration of liver cell fractions

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149209

The possible role of lipid peroxidation in breast cancer risk

27 September 2018

1 reference

12 December 2020

Elevated 4-hydroxylation of estradiol by hamster kidney microsomes: a potential pathway of metabolic activation of estrogens

1 reference

12 December 2020

Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes

1 reference

12 December 2020

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on estrogen metabolism in MCF-7 breast cancer cells: evidence for induction of a novel 17 beta-estradiol 4-hydroxylase

1 reference

12 December 2020

Mechanism of cytochrome P450-catalyzed aromatic hydroxylation of estrogens

1 reference

12 December 2020

Ovary-intact, but not ovariectomized female ACI rats treated with 17beta-estradiol rapidly develop mammary carcinoma

1 reference

12 December 2020

Reactive oxygen species generated from the reaction of copper(II) complexes with biological reductants cause DNA strand scission

1 reference

12 December 2020

Rhythm of the beta-cell oscillator is not governed by a single regulator: multiple systems contribute to oscillatory behavior

1 reference

12 December 2020

Identifiers

DOI

10.1093/CARCIN/BGR109

1 reference

6 August 2017

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6 August 2017

1 reference