(Q35143902)

6 August 2017

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title

New therapeutic target in primary headaches - blocking theCGRP receptor (English)

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6 August 2017

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Lars Edvinsson

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6 August 2017

language of work or name

English

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publication date

1 June 2003

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Expert Opinion on Therapeutic Targets

6 August 2017

published in

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

377-383

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Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Central nervous system binding sites for calcitonin and calcitonin gene-related peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Calcitonin gene-related peptide (CGRP): perivascular distribution and vasodilatory effects.

21 January 2018

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Calcitonin gene-related peptide: functional role in cerebrovascular regulation

21 January 2018

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Innervation of the feline cerebral vasculature by nerve fibers containing calcitonin gene-related peptide: trigeminal origin and co-existence with substance P.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Neuronal messengers in the human cerebral circulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Vasoactive peptide release in the extracerebral circulation of humans during migraine headache

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

The trigeminovascular system and migraine: studies characterizing cerebrovascular and neuropeptide changes seen in humans and cats.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.7.3.377

5-HT(1B) and 5-HT(1D) receptors in the human trigeminal ganglion: co-localization with calcitonin gene-related peptide, substance P and nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

An immunocytochemical investigation of human trigeminal nucleus caudalis: CGRP, substance P and 5-HT1D-receptor immunoreactivities are expressed by trigeminal sensory fibres.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Increase in plasma calcitonin gene-related peptide from the extracerebral circulation during nitroglycerin-induced cluster headache attack

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Responsiveness of the trigeminovascular system to nitroglycerine in cluster headache patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Cutaneous sensory stimulation leading to facial flushing and release of calcitonin gene-related peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Neuropeptide changes in a case of chronic paroxysmal hemicrania--evidence for trigemino-parasympathetic activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

RAMPs: accessory proteins for seven transmembrane domain receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Identification of a protein that confers calcitonin gene-related peptide responsiveness to oocytes by using a cystic fibrosis transmembrane conductance regulator assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

CGRP-RCP, a novel protein required for signal transduction at calcitonin gene-related peptide and adrenomedullin receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Characterization of CGRP(1) receptors in the guinea pig basilar artery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Expression of calcitonin receptor-like receptor and receptor-activity-modifying proteins in human cranial arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Immunohistochemical localization of calcitonin receptor-like receptor and receptor activity-modifying proteins in the human cerebral vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Characterisation of the effects of a non-peptide CGRP receptor antagonist in SK-N-MC cells and isolated human cerebral arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Receptor activity-modifying protein 1 determines the species selectivity of non-peptide CGRP receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Blockade and reversal of spinal morphine tolerance by peptide and non-peptide calcitonin gene-related peptide receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

Effect of the CGRP receptor antagonist BIBN4096BS in human cerebral, coronary and omental arteries and in SK-N-MC cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.377

21 January 2018

Identifiers

DOI

10.1517/14728222.7.3.377

1 reference

6 August 2017

1 reference