(Q35032609)

25409149

5 August 2017

title

IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo (English)

1 reference

5 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Avinashnarayan Venkatanarayan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Payal Raulji

1 reference

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9 June 2020

William Norton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Deepavali Chakravarti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Cristian Coarfa

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Xiaohua Su

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Santosh K Sandur

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Marc S Ramirez

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Jaehuk Lee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Charles V Kingsley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Eliot F Sananikone

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Kimal Rajapakshe

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Katherine Naff

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Jan Parker-Thornburg

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Preethi H Gunaratne

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Elsa R Flores

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

0 references

publication date

17 November 2014

1 reference

5 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

517

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

7536

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

626-630

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

Induced multipotency in adult keratinocytes through down-regulation of ΔNp63 or DGCR8.

9 June 2020

cites work

1 reference

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BRAF inhibitors suppress apoptosis through off-target inhibition of JNK signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Amylin uncovered: a review on the polypeptide responsible for type II diabetes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

TAp63 is a master transcriptional regulator of lipid and glucose metabolism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Comprehensive molecular portraits of human breast tumours

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Comprehensive genomic characterization of squamous cell lung cancers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Comprehensive molecular characterization of human colon and rectal cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Sequence analysis of mutations and translocations across breast cancer subtypes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Glycolytic inhibition alters anaplastic thyroid carcinoma tumor metabolism and improves response to conventional chemotherapy and radiation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

The mutational landscape of head and neck squamous cell carcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Restoring expression of wild-type p53 suppresses tumor growth but does not cause tumor regression in mice with a p53 missense mutation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Regulation of cancer cell metabolism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

p63 and p73 transcriptionally regulate genes involved in DNA repair

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

TAp63 prevents premature aging by promoting adult stem cell maintenance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Pramlintide in the treatment of diabetes mellitus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Restoration of p53 function leads to tumour regression in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

A highly efficient recombineering-based method for generating conditional knockout mutations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene product

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Zp3-cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Tumor spectrum analysis in p53-mutant mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Amyloid peptides are toxic via a common oxidative mechanism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312210

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE13910

Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE13910

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

21 January 2018

2 references

Crossref

https://api.crossref.org/works/10.1038%2FNATURE13910

21 January 2018

12 December 2020

Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium

1 reference

12 December 2020

Amylin-mediated inhibition of insulin-stimulated glucose transport in skeletal muscle

1 reference

12 December 2020

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

12 December 2020

Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE13910

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

release_hmylajeadzhzvb3htngxeomf5e

9 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hmylajeadzhzvb3htngxeomf5e

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

25409149

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409149%20AND%20SRC:MED&resulttype=core&format=json