(Q35027731)

5 August 2017

title

No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans (English)

1 reference

5 August 2017

Heng Li

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David Reich

1 reference

5 August 2017

Ron Do

1 reference

5 August 2017

Daniel Balick

series ordinal

1 reference

5 August 2017

Ivan Adzhubei

series ordinal

1 reference

5 August 2017

Shamil Sunyaev

series ordinal

1 reference

5 August 2017

language of work or name

English

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publication date

12 January 2015

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5 August 2017

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

126-131

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The distribution of deleterious genetic variation in human populations

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins

8 July 2018

1 reference

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Distribution and medical impact of loss-of-function variants in the Finnish founder population

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

The impact of population demography and selection on the genetic architecture of complex traits

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

The deleterious mutation load is insensitive to recent population history

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

The complete genome sequence of a Neanderthal from the Altai Mountains

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Whole-exome sequencing reveals a rapid change in the frequency of rare functional variants in a founding population of humans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Population growth inflates the per-individual number of deleterious mutations and reduces their mean effect

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Predicting functional effect of human missense mutations using PolyPhen-2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

An integrated map of genetic variation from 1,092 human genomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

A high-coverage genome sequence from an archaic Denisovan individual

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Evolution and functional impact of rare coding variation from deep sequencing of human exomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Bayesian inference of ancient human demography from individual genome sequences

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Inference of human population history from individual whole-genome sequences

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Demographic history and rare allele sharing among human populations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Complete Khoisan and Bantu genomes from southern Africa

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Biased gene conversion and the evolution of mammalian genomic landscapes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Fundamental concepts in genetics: Effective population size and patterns of molecular evolution and variation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Assessing the evolutionary impact of amino acid mutations in the human genome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Proportionally more deleterious genetic variation in European than in African populations.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Measurement of the human allele frequency spectrum demonstrates greater genetic drift in East Asians than in Europeans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

Predicting deleterious amino acid substitutions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310772

PSIC: profile extraction from sequence alignments with position-specific counts of independent observations

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.3186

The Jackknife and the Bootstrap for General Stationary Observations

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.3186

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NG.3186

1 reference

5 August 2017

1 reference

5 August 2017

1 reference