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Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe.
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1 reference
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Europe PubMed Central
PubMed publication ID
12478465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
review article
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Europe PubMed Central
title
Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12478465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
main subject
apoptotic process
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author
Maria Castedo
series ordinal
1
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Europe PubMed Central
PubMed publication ID
12478465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
Jean-Luc Perfettini
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2
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Europe PubMed Central
PubMed publication ID
12478465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
Guido Kroemer
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4
object named as
Kroemer G
1 reference
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Europe PubMed Central
PubMed publication ID
12478465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
author name string
Roumier T
series ordinal
3
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Europe PubMed Central
PubMed publication ID
12478465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
publication date
1 December 2002
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Europe PubMed Central
PubMed publication ID
12478465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
published in
Cell Death & Differentiation
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Europe PubMed Central
PubMed publication ID
12478465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
volume
9
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Europe PubMed Central
PubMed publication ID
12478465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
issue
12
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12478465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
page(s)
1287-1293
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12478465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
cites work
Premature p34cdc2 activation required for apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chromatin condensation during apoptosis is accompanied by degradation of lamin A+B, without enhanced activation of cdc2 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc2 activation is not required for thymocyte apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitotic kinases as regulators of cell division and its checkpoints
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Checking out the G(2)/M transition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 negatively regulates cdc2 transcription via the CCAAT-binding NF-Y transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of G2 arrest in response to overexpression of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The anaphase-promoting complex: proteolysis in mitosis and beyond
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A unified view of the DNA-damage checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Organelle-specific initiation of cell death pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Construction by gene targeting in human cells of a "conditional' CDC2 mutant that rereplicates its DNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Flavopiridol, a novel cyclin-dependent kinase inhibitor, in clinical development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-dependent activation of cyclin-dependent kinases during Fas-induced apoptosis in Jurkat cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Temporal relationship of CDK1 activation and mitotic arrest to cytosolic accumulation of cytochrome C and caspase-3 activity during Taxol-induced apoptosis of human AML HL-60 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial control of cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemotherapy: targeting the mitochondrial cell death pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microtubule-targeting drugs induce Bcl-2 phosphorylation and association with Pin1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive Cdc25B tyrosine phosphatase activity in adult brain neurons with M phase-type alterations in Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear localization of cyclin B1 controls mitotic entry after DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The radioresistance to killing of A1-5 cells derives from activation of the Chk1 pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Unscheduled cyclin B expression and p34 cdc2 activation in T lymphocytes from HIV-infected patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exogenous interleukin-2 administration corrects the cell cycle perturbation of lymphocytes from human immunodeficiency virus-infected individuals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus 1 envelope-initiated G2-phase programmed cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The beauty of death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis and karyogamy in syncytia induced by the HIV-1-envelope glycoprotein complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A carboxy-terminally truncated form of the human immunodeficiency virus type 1 Vpr protein induces apoptosis via G(1) cell cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a cytopathogenicity determinant in HIV-1 Vpr.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The C-terminal moiety of HIV-1 Vpr induces cell death via a caspase-independent mitochondrial pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene Defects Clustered at the C-Terminus of the vpr Gene of HIV-1 in Long-Term Nonprogressing Mother and Child Pair:In VivoEvolution of vpr Quasispecies in Blood and Plasma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic characterization of vif, vpr, and vpu sequences from long-term survivors of human immunodeficiency virus type 1 infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation-induced T-cell death is cell cycle dependent and regulated by cyclin B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401130
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.CDD.4401130
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12478465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
PubMed publication ID
12478465
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12478465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12478465%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
ResearchGate publication ID
10994851
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