(Q35020155)

5 August 2017

title

Design and specificity of hammerhead ribozymes against calretinin mRNA. (English)

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5 August 2017

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J Ellis

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5 August 2017

J Rogers

series ordinal

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5 August 2017

language of work or name

English

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publication date

1 November 1993

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5 August 2017

published in

Nucleic Acids Research

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

5171-5178

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A comprehensive set of sequence analysis programs for the VAX

5 August 2017

cites work

1 reference

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8 July 2018

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8 July 2018

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Calretinin: a gene for a novel calcium-binding protein expressed principally in neurons

8 July 2018

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Self-cleavage of virusoid RNA is performed by the proposed 55-nucleotide active site

8 July 2018

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8 July 2018

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8 July 2018

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Specific gene suppression by engineered ribozymes in monkey cells

8 July 2018

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Design of RNA enzymes distinguishing a single base mutation in RNA.

8 July 2018

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CUUCGG hairpins: extraordinarily stable RNA secondary structures associated with various biochemical processes

8 July 2018

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Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites

8 July 2018

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Ribozymes correctly cleave a model substrate and endogenous RNA in vivo

8 July 2018

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Characterization of self-cleavage of viroid and virusoid RNAs

8 July 2018

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A simple single-step procedure for small-scale preparation of Escherichia coli plasmids

8 July 2018

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Ribozymes as potential anti-HIV-1 therapeutic agents.

8 July 2018

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Structure of the human brain calcium-binding protein calretinin and its expression in bacteria

8 July 2018

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Ribozymes that cleave an RNA sequence from human immunodeficiency virus: the effect of flanking sequence on rate

8 July 2018

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Prevention of human immunodeficiency virus type 1 integrase expression in Escherichia coli by a ribozyme

8 July 2018

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Implications of ribozyme kinetics for targeting the cleavage of specific RNA molecules in vivo: more isn't always better

8 July 2018

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Functional characterization of a U5 ribozyme: intracellular suppression of human immunodeficiency virus type 1 expression

8 July 2018

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Ribozymes which cleave arenavirus RNAs: identification of susceptible target sites and inhibition by target site secondary structure

8 July 2018

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Hammerhead ribozyme-mediated cleavage of the long terminal repeat RNA of human immunodeficiency virus type 1.

8 July 2018

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Structural Features that Give Rise to the Unusual Stability of RNA Hairpins Containing GNRA Loops

8 July 2018

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Studies on the structure and stabilizing factor of the CUUCGG hairpin RNA using chemically synthesized oligonucleotides

8 July 2018

1 reference

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Substrate sequence effects on "hammerhead" RNA catalytic efficiency

8 July 2018

1 reference

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Ribozyme-mediated cleavage of c-fos mRNA reduces gene expression of DNA synthesis enzymes and metallothionein

8 July 2018

1 reference

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Minimal sequence requirements for ribozyme activity.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310633

Preformed ribozyme destroys tumour necrosis factor mRNA in human cells

8 July 2018

1 reference

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Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA.

8 July 2018

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Cytoplasmic delivery of ribozymes leads to efficient reduction in alpha-lactalbumin mRNA levels in C127I mouse cells

8 July 2018

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Multitarget-ribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication--potential effectiveness against most presently sequenced HIV-1 isolates

8 July 2018

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Calcium-binding proteins in the nervous system

8 July 2018

1 reference

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Specificity of antisense oligonucleotides in vivo

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310633

Expression of a chimeric ribozyme gene results in endonucleolytic cleavage of target mRNA and a concomitant reduction of gene expression in vivo

8 July 2018

1 reference

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Simple RNA enzymes with new and highly specific endoribonuclease activities

8 July 2018

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A small catalytic oligoribonucleotide

25 October 2018

1 reference

12 December 2020

Construction of a series of several self-cleaving RNA duplexes using synthetic 21-mers

1 reference

12 December 2020

Relationship between 2'-hydroxyls and magnesium binding in the hammerhead RNA domain: a model for ribozyme catalysis

1 reference

12 December 2020

Kinetic Characterization of Ribonuclease-Resistant 2′-Modified Hammerhead Ribozymes

1 reference

12 December 2020

Study of a hammerhead ribozyme containing 2'-modified adenosine residues

1 reference

12 December 2020

Extended target-site specificity for a hammerhead ribozyme

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/21.22.5171

1 reference

5 August 2017

1 reference

5 August 2017

1 reference