(Q35019684)

5 August 2017

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title

Translational control of gene expression and disease (English)

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5 August 2017

Cornelis F Calkhoven

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5 August 2017

Christine Müller

series ordinal

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5 August 2017

Achim Leutz

series ordinal

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5 August 2017

publication date

1 December 2002

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Trends in Molecular Medicine

5 August 2017

published in

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

577-583

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Gene-specific regulation by general translation factors

5 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Perk is essential for translational regulation and cell survival during the unfolded protein response

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Subunits of the translation initiation factor eIF2B are mutant in leukoencephalopathy with vanishing white matter

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

A point mutation in the FMR-1 gene associated with fragile X mental retardation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Functions of the fragile X protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein alpha in myelodysplastic syndromes and acute myeloid leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Mutation in the iron responsive element of the L ferritin mRNA in a family with dominant hyperferritinaemia and cataract

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

AKT plays a central role in tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

PIK3CA is implicated as an oncogene in ovarian cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Regulation of translation initiation by FRAP/mTOR

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Mammalian TOR: a homeostatic ATP sensor

1 reference

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7 January 2021

TOR, a central controller of cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

A role of the kinase mTOR in cellular transformation induced by the oncoproteins P3k and Akt.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

PTEN: life as a tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

The mRNA 5' cap-binding protein, eIF-4E, cooperates with v-myc or E1A in the transformation of primary rodent fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Translational control of the proteome: relevance to cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Overexpression of the proto-oncogene/translation factor 4E in breast-carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Elevated expression of eIF4E in confined early breast cancer lesions: possible role of hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Expression of the eukaryotic translation initiation factors 4E and 2alpha in non-Hodgkin's lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Upregulated expression of the genes encoding translation initiation factors eIF-4E and eIF-2alpha in transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Depletion of intracellular Ca2+ stores, phosphorylation of eIF2alpha, and sustained inhibition of translation initiation mediate the anticancer effects of clotrimazole

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

An analysis of vertebrate mRNA sequences: intimations of translational control

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Translational control of p27Kip1 accumulation during the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Regulated translation initiation controls stress-induced gene expression in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: transcriptional activator lacking antimitotic activity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

A C/EBP beta isoform recruits the SWI/SNF complex to activate myeloid genes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Increased expression of the transcription factors CCAAT-enhancer binding protein-beta (C/EBBeta) and C/EBzeta (CHOP) correlate with invasiveness of human colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

The rapamycin-sensitive signal transduction pathway as a target for cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902424-3

7 January 2021

10.1016/S1471-4914(02)02424-3

Identifiers

DOI

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5 August 2017

1 reference