(Q35014060)

5 August 2017

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title

Chromatin and CD4, CD8A and CD8B gene expression during thymic differentiation (English)

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5 August 2017

Wilfried Ellmeier

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5 August 2017

Dimitris Kioussis

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5 August 2017

publication date

1 December 2002

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Nature Reviews Immunology

5 August 2017

published in

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

909-919

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T-cell development and the CD4-CD8 lineage decision

5 August 2017

cites work

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The CD4/CD8 lineage decision: integration of signalling pathways

21 January 2018

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New perspectives on a developmental dilemma: the kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision

21 January 2018

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T cell development: bottoms-up

21 January 2018

1 reference

Transcriptional regulation in the context of chromatin structure

21 January 2018

1 reference

Unravelling heterochromatin: competition between positive and negative factors regulates accessibility

21 January 2018

1 reference

Nuclease hypersensitive sites in chromatin

21 January 2018

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Cooperation between complexes that regulate chromatin structure and transcription

21 January 2018

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Histone modifications in transcriptional regulation

21 January 2018

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Translating the Histone Code

21 January 2018

1 reference

What does 'chromatin remodeling' mean?

21 January 2018

1 reference

Tissue-specific expression of human CD4 in transgenic mice

21 January 2018

1 reference

Specific expression of the human CD4 gene in mature CD4+ CD8- and immature CD4+ CD8+ T cells and in macrophages of transgenic mice

21 January 2018

1 reference

A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development

21 January 2018

1 reference

Deletion of the CD4 silencer element supports a stochastic mechanism of thymocyte lineage commitment

21 January 2018

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The regulation of CD4 and CD8 coreceptor gene expression during T cell development

21 January 2018

1 reference

B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.

21 January 2018

1 reference

Elf-1 binds to a critical element in a second CD4 enhancer

21 January 2018

1 reference

Positive selection induces CD4 promoter and enhancer function.

21 January 2018

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Identification and characterization of a T-cell-specific enhancer adjacent to the murine CD4 gene

21 January 2018

1 reference

Reconstitution of the subclass-specific expression of CD4 in thymocytes and peripheral T cells of transgenic mice: identification of a human CD4 enhancer

21 January 2018

1 reference

The notch pathway intermediate HES-1 silences CD4 gene expression

21 January 2018

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Subclass-specific nuclear localization of a novel CD4 silencer binding factor

21 January 2018

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Negative regulation of CD4 gene expression by a HES-1-c-Myb complex

21 January 2018

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Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation.

21 January 2018

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The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells

21 January 2018

1 reference

An enhancer that directs lineage-specific expression of CD8 in positively selected thymocytes and mature T cells

21 January 2018

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Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells.

21 January 2018

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Hierarchical interactions of control elements determine CD8alpha gene expression in subsets of thymocytes and peripheral T cells.

21 January 2018

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CD8 expression up to the double-positive CD3(low/intermediate) stage of thymic differentiation is sufficient for development of peripheral functional cytotoxic T lymphocytes

21 January 2018

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Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression.

21 January 2018

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Variegated expression of CD8 alpha resulting from in situ deletion of regulatory sequences.

21 January 2018

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DNA methylation and chromatin - unraveling the tangled web.

21 January 2018

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Each hypersensitive site of the human beta-globin locus control region confers a different developmental pattern of expression on the globin genes.

21 January 2018

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A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

21 January 2018

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Association of Transcriptionally Silent Genes with Ikaros Complexes at Centromeric Heterochromatin

21 January 2018

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Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding

21 January 2018

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Computer-assisted search for sites of nuclear matrix attachment.

21 January 2018

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Interaction of the Nuclear Matrix-associated Region (MAR)-Binding Proteins, SATB1 and CDP/Cux, with a MAR Element (L2a) in an Upstream Regulatory Region of the Mouse CD8a Gene

21 January 2018

1 reference

Identification of a candidate regulatory region in the human CD8 gene complex by colocalization of DNase I hypersensitive sites and matrix attachment regions which bind SATB1 and GATA-3

21 January 2018

1 reference

HMG domain proteins: architectural elements in the assembly of nucleoprotein structures

21 January 2018

1 reference

Human HMG box transcription factor HBP1: a role in hCD2 LCR function

21 January 2018

1 reference

Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

21 January 2018

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TOX: an HMG box protein implicated in the regulation of thymocyte selection

21 January 2018

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Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes

21 January 2018

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Epigenetic regulation of T cell fate and function

21 January 2018

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Haematopoietic cell-fate decisions, chromatin regulation and ikaros

21 January 2018

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Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes

21 January 2018

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Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation

21 January 2018

1 reference

Structure of the mouse gene encoding CD4 and an unusual transcript in brain

21 January 2018

1 reference

T cell-specific protein-DNA interactions occurring at the CD4 locus: identification of possible transcriptional control elements of the murine CD4 gene

21 January 2018

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Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

21 January 2018

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MARs of antigen receptor and co-receptor genes.

21 January 2018

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Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage

21 January 2018

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Thymocytes control the CD4 gene differently from mature T lymphocytes

21 January 2018

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Asymmetric redundancy in CD4 silencer function

21 January 2018

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Subsets of CD3+ (T cell receptor α/β or γ/δ) and CD3− lymphocytes isolated from normal human gut epithelium display phenotypical features different from their counterparts in peripheral blood

21 January 2018

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A Region in the CD8 Gene Locus That Directs Expression to the Mature CD8 T Cell Subset in Transgenic Mice

21 January 2018

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Human CD8 alpha expression in NK cells but not cytotoxic T cells of transgenic mice

21 January 2018

1 reference

Human CD2 3'-flanking sequences confer high-level, T cell-specific, position-independent gene expression in transgenic mice

21 January 2018

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Specific demethylation of the CD4 gene during CD4 T lymphocyte differentiation

21 January 2018

1 reference

Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4.

21 January 2018

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A transcriptional silencer controls the developmental expression of the CD4 gene.

31 March 2020

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The CD8alpha gene locus is regulated by the Ikaros family of proteins

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRI952

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Dimensions Publication ID

5 August 2017

1034846238

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