(Q35095605)

6 August 2017

title

Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis (English)

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6 August 2017

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Qutayba Hamid

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6 August 2017

Nives Zimmermann

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6 August 2017

Nina E King

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6 August 2017

Johanne Laporte

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6 August 2017

Ming Yang

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6 August 2017

Anil Mishra

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6 August 2017

Sam M Pope

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6 August 2017

Emily E Muntel

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6 August 2017

David P Witte

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6 August 2017

Anthony A Pegg

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6 August 2017

Paul S Foster

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6 August 2017

Marc E Rothenberg

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6 August 2017

language of work or name

English

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publication date

1 June 2003

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Journal of Clinical Investigation

6 August 2017

published in

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6 August 2017

volume

111

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6 August 2017

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6 August 2017

page(s)

1863-1874

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Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen

6 August 2017

cites work

1 reference

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9 July 2018

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Regulation of enzymes of the urea cycle and arginine metabolism

9 July 2018

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Macrophage arginine metabolism to ornithine/urea or nitric oxide/citrulline: a life or death issue.

9 July 2018

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Activities of arginase I and II are limiting for endothelial cell proliferation

9 July 2018

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9 July 2018

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Elevated arginase I expression in rat aortic smooth muscle cells increases cell proliferation

9 July 2018

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Pulmonary T cells and eosinophils: coconspirators or independent triggers of allergic respiratory pathology?

9 July 2018

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Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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IL-12/IL-13 axis in allergic asthma

9 July 2018

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9 July 2018

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Murine eotaxin-2: a constitutive eosinophil chemokine induced by allergen challenge and IL-4 overexpression

9 July 2018

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IL-4 and IL-13 upregulate arginase I expression by cAMP and JAK/STAT6 pathways in vascular smooth muscle cells

9 July 2018

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Airway nitrogen oxide measurements in asthma and other pediatric respiratory diseases

9 July 2018

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New directions in allergic diseases: mechanism-based anti-inflammatory therapies

9 July 2018

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Molecular mechanisms of increased nitric oxide (NO) in asthma: evidence for transcriptional and post-translational regulation of NO synthesis

9 July 2018

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Polyamines in the lung: polyamine uptake and polyamine-linked pathological or toxicological conditions

9 July 2018

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The epidemic of allergy and asthma

9 July 2018

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Airway remodeling in asthma

9 July 2018

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Th2 cells and GATA-3 in asthma: new insights into the regulation of airway inflammation

9 July 2018

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Th1/Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells

9 July 2018

1 reference

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Dual action of iNOS-derived nitric oxide in allergen-induced airway hyperreactivity in conscious, unrestrained guinea pigs

9 July 2018

1 reference

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Effect of endogenous nitric oxide inhibition on airway responsiveness to histamine and adenosine-5'-monophosphate in asthma

9 July 2018

1 reference

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The human arginases and arginase deficiency

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Eotaxin is required for the baseline level of tissue eosinophils

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Role of nitric oxide in the development and partial reversal of allergen-induced airway hyperreactivity in conscious, unrestrained guinea-pigs

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophilia

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Deficiency of nitric oxide in allergen-induced airway hyperreactivity to contractile agonists after the early asthmatic reaction: an ex vivo study

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Sorting out the cytokines of asthma

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Immunological aspects of allergic asthma

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

The relationship between the free pool of proline and collagen content in human liver cirrhosis.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

A murine model of allergic bronchopulmonary aspergillosis with elevated eosinophils and IgE

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Elevated levels of peripheral‐blood, naturally occurring aliphatic polyamines in bronchial asthmatic patients with active symptoms

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Modulation of potassium channels in the hearts of transgenic and mutant mice with altered polyamine biosynthesis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

The role of polyamines in gastric mucus synthesis inhibited by cigarette smoke or its extract.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Requirement for IL-13 independently of IL-4 in experimental asthma

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Purification of a multipotent antideath activity from bovine liver and its identification as arginase: nitric oxide-independent inhibition of neuronal apoptosis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Nitric oxide synthesis inhibitors induce airway hyperresponsiveness in the guinea pig in vivo and in vitro. Role of the epithelium

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161427

Interleukin-5-mediated allergic airway inflammation inhibits the human surfactant protein C promoter in transgenic mice

27 September 2018

1 reference

12 December 2020

IL-13 induces eosinophil recruitment into the lung by an IL-5- and eotaxin-dependent mechanism

1 reference

12 December 2020

Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, November 1986

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12 December 2020

Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma

1 reference

12 December 2020

Effects of polyamines on intracellular calcium and mechanical activity in smooth muscle of guinea-pig taenia coli

1 reference

12 December 2020

Role of ornithine as a proline precursor in healing wounds

1 reference

12 December 2020

Particulate Aspergillus fumigatus antigens elicit a TH2 response in BALB/c mice

1 reference

12 December 2020

Polyamines inhibit myosin phosphatase and increase LC20 phosphorylation and force in smooth muscle

1 reference

12 December 2020

IL-4 and IL-5 mRNA expression in induced sputum of asthmatic subjects: comparison with bronchial wash

1 reference

12 December 2020

Cationic proteins inhibit L-arginine uptake in rat alveolar macrophages and tracheal epithelial cells. Implications for nitric oxide synthesis

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI200317912

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6 August 2017

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6 August 2017

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