(Q35079256)

6 August 2017

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title

Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members (English)

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6 August 2017

Rudi Beyaert

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6 August 2017

Sophie Janssens

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6 August 2017

language of work or name

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1 February 2003

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6 August 2017

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

293-302

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Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Translocation of the interleukin-1 receptor-associated kinase-1 (IRAK-1) into the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

IRAK: a kinase associated with the interleukin-1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

TRAF6 is a signal transducer for interleukin-1

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Functional analysis of the interleukin-1-receptor-associated kinase (IRAK-1) in interleukin-1 beta-stimulated nuclear factor kappa B (NF-kappa B) pathway activation: IRAK-1 associates with the NF-kappa B essential modulator (NEMO) upon receptor stim

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

NF-kappa B activation by interleukin-1 (IL-1) requires an IL-1 receptor-associated protein kinase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Dorsal, a Drosophila Rel-like protein, is phosphorylated upon activation of the transmembrane protein Toll

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

TIRAP: an adapter molecule in the Toll signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

A universal role for MyD88 in TLR/IL-1R-mediated signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

IRAK1b, a novel alternative splice variant of interleukin-1 receptor-associated kinase (IRAK), mediates interleukin-1 signaling and has prolonged stability

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Active and inactive protein kinases: structural basis for regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Effects of IL-1 receptor-associated kinase (IRAK) expression on IL-1 signaling are independent of its kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Effects of overexpression of IL-1 receptor-associated kinase on NFkappaB activation, IL-2 production and stress-activated protein kinases in the murine T cell line EL4.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

IRAK-M is a negative regulator of Toll-like receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

IL-1-induced NFkappa B and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK)

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Identification of interleukin 1 receptor-associated kinase as a conserved component in the p75-neurotrophin receptor activation of nuclear factor-kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Interleukin-1-induced activation of a protein kinase co-precipitating with the type I interleukin-1 receptor in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-κB

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Toll-like receptors and innate immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Assignment of homologous genes, Peli1/PELI1 and Peli2/PELI2, for the Pelle adaptor protein Pellino to mouse chromosomes 11 and 14 and human chromosomes 2p13.3 and 14q21, respectively, by physical and radiation hybrid mapping

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Identification and characterization of murine IRAK-M

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

IL-1 and IL-18 receptors, and their extended family.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

IL-1 receptor-associated kinase modulates host responsiveness to endotoxin.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Developmental and tissue-specific expression of mouse pelle-like protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Modulation of tumor necrosis factor and interleukin-1-dependent NF-kappaB activity by mPLK/IRAK.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

SIMPL is a tumor necrosis factor-specific regulator of nuclear factor-kappaB activity

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

The death domain superfamily: a tale of two interfaces?

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

The Interleukin-1 Receptor-associated Kinase Is Degraded by Proteasomes following Its Phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Distinct molecular mechanism for initiating TRAF6 signalling

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Cutting edge: mouse pellino-2 modulates IL-1 and lipopolysaccharide signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

The Drosophila tumor necrosis factor receptor-associated factor-1 (DTRAF1) interacts with Pelle and regulates NFkappaB activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

Negative regulation of toll-like receptor-mediated signaling by Tollip

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900053-4

7 January 2021

10.1016/S1097-2765(03)00053-4

Identifiers

DOI

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6 August 2017

1 reference