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Proteomics: the first decade and beyond

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Europe PubMed Central

PubMed publication ID

6 August 2017

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Europe PubMed Central

Proteomics: the first decade and beyond (English)

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Europe PubMed Central

PubMed publication ID

6 August 2017

author name string

Scott D Patterson

1

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Europe PubMed Central

PubMed publication ID

6 August 2017

Ruedi H Aebersold

2

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Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

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publication date

1 March 2003

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Europe PubMed Central

PubMed publication ID

6 August 2017

Nature Genetics

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Europe PubMed Central

PubMed publication ID

6 August 2017

33 Suppl

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Europe PubMed Central

PubMed publication ID

6 August 2017

311-323

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Europe PubMed Central

PubMed publication ID

6 August 2017

Equipping scientists for the new biology

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Structural genomics takes off.

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7 January 2021

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Quantitative monitoring of gene expression patterns with a complementary DNA microarray

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7 January 2021

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Serial analysis of gene expression

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Internal amino acid sequence analysis of proteins separated by one- or two-dimensional gel electrophoresis after in situ protease digestion on nitrocellulose

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Protein-blotting on Polybrene-coated glass-fiber sheets. A basis for acid hydrolysis and gas-phase sequencing of picomole quantities of protein previously separated on sodium dodecyl sulfate/polyacrylamide gel.

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Internal sequence analysis of proteins separated on polyacrylamide gels at the submicrogram level: improved methods, applications and gene cloning strategies

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Complementary DNA sequencing: expressed sequence tags and human genome project

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7 January 2021

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3,400 new expressed sequence tags identify diversity of transcripts in human brain

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7 January 2021

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Gene expression profiles in normal and cancer cells

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7 January 2021

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Normalization and subtraction: two approaches to facilitate gene discovery

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7 January 2021

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Life with 6000 genes

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The Sequence of the Human Genome

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Initial sequencing and analysis of the human genome

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7 January 2021

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Electrospray ionization for mass spectrometry of large biomolecules

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7 January 2021

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Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons

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7 January 2021

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Protein and polymer analyses up tom/z 100 000 by laser ionization time-of-flight mass spectrometry

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Identifying proteins from two-dimensional gels by molecular mass searching of peptide fragments in protein sequence databases

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Use of mass spectrometric molecular weight information to identify proteins in sequence databases

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7 January 2021

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Rapid identification of proteins by peptide-mass fingerprinting

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7 January 2021

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Protein identification by mass profile fingerprinting.

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7 January 2021

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Peptide mass maps: a highly informative approach to protein identification

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7 January 2021

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Mass spectrometric approaches for the identification of gel-separated proteins

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7 January 2021

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An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

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7 January 2021

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Electrospray and Taylor-Cone theory, Dole's beam of macromolecules at last?

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Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry

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7 January 2021

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Proteomics: applications in basic and applied biology

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7 January 2021

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Progress with proteome projects: why all proteins expressed by a genome should be identified and how to do it.

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Correlation between protein and mRNA abundance in yeast

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7 January 2021

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Prognostic value of plasma interleukin-6 levels in patients with chronic lymphocytic leukemia

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Reference distributions for the negative acute-phase proteins, albumin, transferrin, and transthyretin: a comparison of a large cohort to the world's literature

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7 January 2021

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Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology

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7 January 2021

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Analysis of the mouse proteome. (I) Brain proteins: separation by two-dimensional electrophoresis and identification by mass spectrometry and genetic variation

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7 January 2021

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Two-dimensional gel electrophoresis in proteomics: old, old fashioned, but it still climbs up the mountains

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7 January 2021

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Advances in protein solubilisation for two-dimensional electrophoresis

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7 January 2021

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Difference gel electrophoresis. A single gel method for detecting changes in protein extracts

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7 January 2021

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A comparison between Sypro Ruby and ruthenium II tris (bathophenanthroline disulfonate) as fluorescent stains for protein detection in gels

1 reference

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7 January 2021

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Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry

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HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation

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7 January 2021

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Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad

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7 January 2021

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Direct Analysis of Protein Mixtures by Tandem Mass Spectrometry

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7 January 2021

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IPPC '99. Proceedings of the 1st Pacific Rim 2-DE Meeting. Tokyo, Japan, August 29-September 1, 1999

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An automated multidimensional protein identification technology for shotgun proteomics

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7 January 2021

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Direct analysis of protein complexes using mass spectrometry

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Purification and biochemical characterization of interchromatin granule clusters

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Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition

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7 January 2021

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Towards defining the urinary proteome using liquid chromatography-tandem mass spectrometry. I. Profiling an unfractionated tryptic digest

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7 January 2021

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Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry

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7 January 2021

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Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes

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7 January 2021

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Quantitative profiling of differentiation-induced microsomal proteins using isotope-coded affinity tags and mass spectrometry

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7 January 2021

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The yeast nuclear pore complex: composition, architecture, and transport mechanism

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7 January 2021

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Large-scale analysis of the yeast proteome by multidimensional protein identification technology

1 reference

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7 January 2021

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Electrospray ionization mass spectrometry of phosphopeptides isolated by on-line immobilized metal-ion affinity chromatography

1 reference

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7 January 2021

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Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae

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7 January 2021

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Specific isolation of O-linked N-acetylglucosamine glycopeptides from complex mixtures

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7 January 2021

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Selective Detection and Site-Analysis of O-GlcNAc-Modified Glycopeptides by β-Elimination and Tandem Electrospray Mass Spectrometry

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Automated LC-LC-MS-MS platform using binary ion-exchange and gradient reversed-phase chromatography for improved proteomic analyses

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7 January 2021

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Proteome analysis of low-abundance proteins using multidimensional chromatography and isotope-coded affinity tags

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7 January 2021

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An accurate mass tag strategy for quantitative and high-throughput proteome measurements

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7 January 2021

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Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

1 reference

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7 January 2021

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Quantitation and facilitated de novo sequencing of proteins by isotopic N-terminal labeling of peptides with a fragmentation-directing moiety

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De novo peptide sequencing and quantitative profiling of complex protein mixtures using mass-coded abundance tagging

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7 January 2021

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Quantitative proteome analysis by solid-phase isotope tagging and mass spectrometry

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7 January 2021

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Quantitation of peptides and proteins by matrix-assisted laser desorption/ionization mass spectrometry using (18)O-labeled internal standards

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7 January 2021

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Proteolytic 18O labeling for comparative proteomics: model studies with two serotypes of adenovirus

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7 January 2021

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Accurate quantitation of protein expression and site-specific phosphorylation

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7 January 2021

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7 January 2021

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7 January 2021

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Analysis of quantitative proteomic data generated via multidimensional protein identification technology

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Molecular features of B-cell lymphoma

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles

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7 January 2021

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Cluster analysis and display of genome-wide expression patterns

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7 January 2021

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Singular value decomposition for genome-wide expression data processing and modeling

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7 January 2021

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Integrated genomic and proteomic analyses of a systematically perturbed metabolic network

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7 January 2021

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7 January 2021

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A sampling of the yeast proteome

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7 January 2021

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7 January 2021

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1 reference

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7 January 2021

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Profiling the specific reactivity of the proteome with non-directed activity-based probes

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7 January 2021

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Proteomic profiling of mechanistically distinct enzyme classes using a common chemotype

1 reference

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7 January 2021

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Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools

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7 January 2021

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7 January 2021

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1 reference

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7 January 2021

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Chemical strategies for the global analysis of protein function

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7 January 2021

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Chemical approaches for functionally probing the proteome

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7 January 2021

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Profiling serine hydrolase activities in complex proteomes

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7 January 2021

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Activity-based protein profiling: the serine hydrolases

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7 January 2021

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Approaches to labeling and identification of active site residues in glycosidases

1 reference

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7 January 2021

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Gamma-phosphate-linked ATP-sepharose for the affinity purification of protein kinases. Rapid purification to homogeneity of skeletal muscle mitogen-activated protein kinase kinase

1 reference

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7 January 2021

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Mass spectrometry in coupling with affinity capture-release and isotope-coded affinity tags for quantitative protein analysis

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7 January 2021

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Affinity chromatography on immobilized anhydrotrypsin: general utility for selective isolation of C-terminal peptides from protease digests of proteins

1 reference

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7 January 2021

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Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing

1 reference

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7 January 2021

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Identification of incompletely processed potential carboxypeptidase E substrates from CpEfat/CpEfat mice

1 reference

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7 January 2021

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Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases

1 reference

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7 January 2021

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Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1

1 reference

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7 January 2021

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Immobilized metal ion affinity chromatography. Effect of solute structure, ligand density and salt concentration on the retention of peptides

1 reference

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7 January 2021

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Immobilized gallium(III) affinity chromatography of phosphopeptides

1 reference

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7 January 2021

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Enrichment analysis of phosphorylated proteins as a tool for probing the phosphoproteome

1 reference

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7 January 2021

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Phosphoprotein isotope-coded affinity tag approach for isolating and quantitating phosphopeptides in proteome-wide analyses

1 reference

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7 January 2021

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A systematic approach to the analysis of protein phosphorylation

1 reference

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7 January 2021

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Proteomics to study genes and genomes

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7 January 2021

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Charting the protein complexome in yeast by mass spectrometry.

1 reference

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7 January 2021

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From molecular to modular cell biology

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7 January 2021

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Functional organization of the yeast proteome by systematic analysis of protein complexes

1 reference

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7 January 2021

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Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

1 reference

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7 January 2021

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Comparative assessment of large-scale data sets of protein-protein interactions

1 reference

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7 January 2021

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The study of macromolecular complexes by quantitative proteomics

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7 January 2021

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Light-generated oligonucleotide arrays for rapid DNA sequence analysis

1 reference

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7 January 2021

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Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer

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7 January 2021

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DNA microarrays: raising the profile

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7 January 2021

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Statistical issues with microarrays: processing and analysis

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7 January 2021

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Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions

1 reference

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7 January 2021

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Arrays for protein expression profiling: towards a viable alternative to two-dimensional gel electrophoresis?

1 reference

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7 January 2021

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Solution and chip arrays in protein profiling

1 reference

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7 January 2021

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Phage antibodies: filamentous phage displaying antibody variable domains

1 reference

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7 January 2021

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The making of the minibody: an engineered beta-protein for the display of conformationally constrained peptides

1 reference

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7 January 2021

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Coupling protein design and in vitro selection strategies: improving specificity and affinity of a designed beta-protein IL-6 antagonist

1 reference

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7 January 2021

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Tendamistat as a scaffold for conformationally constrained phage peptide libraries

1 reference

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7 January 2021

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A combinatorial library of an alpha-helical bacterial receptor domain

1 reference

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7 January 2021

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Designing DNA-binding proteins on the surface of filamentous phage

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7 January 2021

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The use of aptamers in large arrays for molecular diagnostics

1 reference

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7 January 2021

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The use of recombinant antibodies in proteomics

1 reference

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7 January 2021

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Anti-idiotypic protein domains selected from protein A-based affibody libraries

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A perspective on protein microarrays

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein and antibody arrays and their medical applications.

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein arrays for gene expression and molecular interaction screening

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiplexed protein profiling on microarrays by rolling-circle amplification

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Towards quantitative assays with peptide chips: a surface engineering approach

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

A biochemical genomics approach for identifying genes by the activity of their products.

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Peptide chips for the quantitative evaluation of protein kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of yeast protein kinases using protein chips.

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Genome-wide location and function of DNA binding proteins

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Massive parallel analysis of the binding specificity of histone-like protein HU to single- and double-stranded DNA with generic oligodeoxyribonucleotide microchips

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Large-scale identification of secreted and membrane-associated gene products using DNA microarrays

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Messenger RNA translation state: the second dimension of high-throughput expression screening

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein nanoarrays generated by dip-pen nanolithography

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel genetic system to detect protein-protein interactions

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Towards an understanding of complex protein networks

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

A protein linkage map of Escherichia coli bacteriophage T7.

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Genome-wide analysis of vaccinia virus protein-protein interactions

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Toward a protein-protein interaction map of the budding yeast: A comprehensive system to examine two-hybrid interactions in all possible combinations between the yeast proteins

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

A comprehensive two-hybrid analysis to explore the yeast protein interactome

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

The protein-protein interaction map of Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein interaction mapping in C. elegans using proteins involved in vulval development

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

A protein-protein interaction map of the Caenorhabditis elegans 26S proteasome

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Yeast three-hybrid system to detect and analyze RNA-protein interactions

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

A yeast sensor of ligand binding.

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Wavelength mutations and posttranslational autoxidation of green fluorescent protein

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

The green fluorescent protein

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Seeing the machinery of live cells

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Subcellular localization of the yeast proteome

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

YPD-A database for the proteins of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

SGD: Saccharomyces Genome Database

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantitative proteomic analysis of Myc oncoprotein function

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Base-calling of automated sequencer traces using phred. I. Accuracy assessment

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Base-calling of automated sequencer traces using phred. II. Error probabilities

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Experimental Protein Mixture for Validating Tandem Mass Spectral Analysis

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular Imaging of Biological Samples: Localization of Peptides and Proteins Using MALDI-TOF MS

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Resonance shifts in the excitation of the n = 0, K = 1 to 6 quadrupolar resonances for ions confined in a linear ion trap.

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

The characteristics of peptide collision-induced dissociation using a high-performance MALDI-TOF/TOF tandem mass spectrometer

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Fourier transform ion cyclotron resonance mass spectrometry: a primer

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Cartography of neurexins: more than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Use of proteomic patterns in serum to identify ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Robustness in bacterial chemotaxis

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

inferred from DOI database lookup

Combinatorial synthesis of genetic networks

1 reference

https://api.crossref.org/works/10.1038%2FNG1106

7 January 2021

based on heuristic

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Identifiers

1 reference

https://api.fatcat.wiki/v0/release/bnfld3gzjbcq5hk236bs4c44g4

30 July 2022

based on heuristic

mapped directly with Wikidata item

release_bnfld3gzjbcq5hk236bs4c44g4

1 reference

https://api.fatcat.wiki/v0/release/bnfld3gzjbcq5hk236bs4c44g4

30 July 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

https://api.fatcat.wiki/v0/release/bnfld3gzjbcq5hk236bs4c44g4

30 July 2022

based on heuristic

mapped directly with Wikidata item

ResearchGate publication ID

0 references

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