(Q35072094)

6 August 2017

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title

Contrasting alloreactive CD4+ and CD8+ T cells: there's more to it than MHC restriction (English)

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6 August 2017

Keri L Csencsits

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D Keith Bishop

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6 August 2017

language of work or name

English

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publication date

1 February 2003

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American Journal of Transplantation

6 August 2017

published in

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

107-115

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Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation

6 August 2017

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Differential association of CD45 isoforms with CD4 and CD8 regulates the actions of specific pools of p56lck tyrosine kinase in T cell antigen receptor signal transduction

21 January 2018

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Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells

21 January 2018

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The amplification of TCR signaling by dynamic membrane microdomains

21 January 2018

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CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes

21 January 2018

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T cell receptor signaling precedes immunological synapse formation

21 January 2018

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Assembly of the immunological synapse for T cells and NK cells

21 January 2018

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T cell apoptosis in human heart allografts: association with lack of co-stimulation?

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

CD103+ CTL accumulate within the graft epithelium during clinical renal allograft rejection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Cutting edge: antigen-independent CD8 T cell proliferation.

21 January 2018

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Bystander activation of CD8+ T cells contributes to the rapid production of IFN-gamma in response to bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Cutting edge: increased expression of Bcl-2 in antigen-specific memory CD8+ T cells

21 January 2018

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Helper activity is required for the in vivo generation of cytotoxic T lymphocytes

21 January 2018

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Help for cytotoxic-T-cell responses is mediated by CD40 signalling

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions

21 January 2018

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The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses

21 January 2018

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Cutting edge: membrane lymphotoxin regulates CD8(+) T cell-mediated intestinal allograft rejection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Genetic characterization of strain differences in the ability to mediate CD40/CD28-independent rejection of skin allografts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

CD4+ but not CD8+ cells are essential for allorejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Interferon-gamma acts directly on rejecting renal allografts to prevent graft necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

A role for eosinophils in transplant rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Regulating the immune response to transplants. a role for CD4+ regulatory cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Cytokines induce the development of functionally heterogeneous T helper cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Transcriptional regulation of Th1/Th2 polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Transcription Factor GATA-3 Is Differentially Expressed in Murine Th1 and Th2 Cells and Controls Th2-specific Expression of the Interleukin-5 Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

A novel transcription factor, T-bet, directs Th1 lineage commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Lineage-specific requirement for signal transducer and activator of transcription (Stat)4 in interferon gamma production from CD4(+) versus CD8(+) T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Interleukin-18 regulates both Th1 and Th2 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

IL-12p40-dependent agonistic effects on the development of protective innate and adaptive immunity against Salmonella enteritidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Regulation of immune responses by TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

DNA-liposome versus adenoviral mediated gene transfer of transforming growth factor beta1 in vascularized cardiac allografts: differential sensitivity of CD4+ and CD8+ T cells to transforming growth factor beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

The pleiotropic functions of interleukin 15: not so interleukin 2-like after all.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

IL-15: a pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

The growth of the very large CD8+ T cell clones in older mice is controlled by cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

IL-15 and IL-2: a matter of life and death for T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

An antagonist IL-15/Fc protein prevents costimulation blockade-resistant rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

The role of T-cell costimulatory activation pathways in transplant rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

The future of organ and tissue transplantation: can T-cell costimulatory pathway modifiers revolutionize the prevention of graft rejection?

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

The role of TNF receptor and TNF superfamily molecules in organ transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Naive CD8+ T cells do not require costimulation for proliferation and differentiation into cytotoxic effector cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Role of CD28 for the generation and expansion of antigen-specific CD8(+) T lymphocytes during infection with Listeria monocytogenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Listeria monocytogenes infection overcomes the requirement for CD40 ligand in exogenous antigen presentation to CD8(+) T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

A critical role for CD40-CD40 ligand interactions in amplification of the mucosal CD8 T cell response

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

T cell co-stimulatory molecules other than CD28.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Role of 4-1BB in immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Human 4-1BB regulates CD28 co-stimulation to promote Th1 cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Role of CD40 Ligand and CD28 in Induction and Maintenance of Antiviral CD8+ Effector T Cell Responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Cutting Edge: Precursor Frequency Affects the Helper Dependence of Cytotoxic T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Cutting edge: CD4 and CD8 T cells are intrinsically different in their proliferative responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Differential Survival of Naive CD4 and CD8 T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Multiple paths for activation of naive CD8+ T cells: CD4-independent help

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

CD8+ T cells are capable of rejecting pancreatic islet xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Immunobiology of allograft rejection in the absence of IFN-gamma: CD8+ effector cells develop independently of CD4+ cells and CD40-CD40 ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

The immunobiology of inductive anti-CD40L therapy in transplantation: allograft acceptance is not dependent upon the deletion of graft-reactive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

IL-5 and eosinophils mediate the rejection of fully histoincompatible vascularized cardiac allografts: regulatory role of alloreactive CD8(+) T lymphocytes and IFN-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Selective blockade of IL-15 by soluble IL-15 receptor alpha-chain enhances cardiac allograft survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

CD40-CD40 ligand-independent activation of CD8+ T cells can trigger allograft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

4-1BB ligand-mediated costimulation of human T cells induces CD4 and CD8 T cell expansion, cytokine production, and the development of cytolytic effector function

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Functional subclasses of T lymphocytes bearing different Ly antigens. II. Cooperation between subclasses of Ly+ cells in the generation of killer activity

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Precursor frequency analysis of lymphokine-secreting alloreactive T lymphocytes. Dissociation of subsets producing interleukin 2, macrophage-activating factor, and granulocyte-macrophage colony-stimulating factor on the basis of Lyt-2 phenotype

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen-Reactivity

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Coreceptors and adapter proteins in T-cell signaling

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Molecular biology and function of CD4 and CD8

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Alloreactive cloned T cell lines. I. Interactions between cloned amplifier and cytolytic T cell lines

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Phenotype, specificity, and function of T cell subsets and T cell interactions involved in skin allograft rejection

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Cellular basis of skin allograft rejection: an in vivo model of immune-mediated tissue destruction

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Islet allograft survival after a single course of treatment of recipient with antibody to L3T4

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Evidence that long-term cardiac allograft survival induced by anti-CD4 monoclonal antibody does not require depletion of CD4+ T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Acute rejection of cardiac allografts by noncytolytic CD4(+) T cell populations

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Transfusion of polarized TH2-like cell populations into SCID mouse cardiac allograft recipients results in acute allograft rejection

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

CD8+ T cell subsets TC1 and TC2 cause different histopathologic forms of murine cardiac allograft rejection

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Critical roles for IL-4, IL-5, and eosinophils in chronic skin allograft rejection

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Are Th2 helper T lymphocytes beneficial, deleterious, or irrelevant in promoting allograft survival?

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Human TH1 and TH2 subsets: doubt no more

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

The functional role of CD8+ T helper type 2 cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Interleukin-12 antagonist activity of mouse interleukin-12 p40 homodimer in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

Intragraft IL-15 transcripts are increased in human renal allograft rejection

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2003.00036.X

7 January 2021

10.1034/J.1600-6143.2003.00036.X

Identifiers

DOI

1 reference

6 August 2017

1 reference