(Q35058908)

6 August 2017

title

A role for IL-27 in limiting T regulatory cell populations (English)

1 reference

6 August 2017

A Role for IL-27 in Limiting T Regulatory Cell Populations (English)

1 reference

Crossref

DOI

10.4049/JIMMUNOL.1004182

https://api.crossref.org/works/10.4049/JIMMUNOL.1004182

3 December 2024

Jason S Stumhofer

1 reference

6 August 2017

Nancy Hosken

1 reference

6 August 2017

Aisling C O'Hara Hall

object named as

Aisling C O'Hara

1 reference

6 August 2017

Elizabeth Mauldin

1 reference

6 August 2017

Qun Fang

1 reference

6 August 2017

Elia D. Tait Wojno

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21622862

3 December 2024

Aisling C. O'Hara

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21622862

3 December 2024

Laurence A. Turka

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21622862

3 December 2024

Steven D. Levin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21622862

3 December 2024

Christopher A. Hunter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21622862

3 December 2024

language of work or name

English

0 references

publication date

27 May 2011

1 reference

full work available at URL

6 August 2017

http://www.jimmunol.org/content/jimmunol/187/1/266.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21622862

https://europepmc.org/articles/PMC3119737

3 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21622862

https://europepmc.org/articles/PMC3119737?pdf=render

3 December 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21622862

https://doi.org/10.4049/jimmunol.1004182

3 December 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21622862

https://journals.aai.org/jimmunol/article-pdf/187/1/266/1340301/1004182.pdf

3 December 2024

file format

Portable Document Format

1 reference

Crossref

DOI

10.4049/JIMMUNOL.1004182

https://api.crossref.org/works/10.4049/JIMMUNOL.1004182

3 December 2024

published in

Journal of Immunology

1 reference

6 August 2017

volume

187

1 reference

6 August 2017

1 reference

6 August 2017

page(s)

266-273

1 reference

IL-27 promotes T cell-dependent colitis through multiple mechanisms

6 August 2017

cites work

1 reference

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Regulatory T cells exert checks and balances on self tolerance and autoimmunity

8 July 2018

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Immunologic and therapeutic synergy of IL-27 and IL-2: enhancement of T cell sensitization, tumor-specific CTL reactivity and complete regression of disseminated neuroblastoma metastases in the liver and bone marrow

8 July 2018

1 reference

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Altering regulatory T cell function in cancer immunotherapy: a novel means to boost the efficacy of cancer vaccines

8 July 2018

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Interleukin-2 in the development and control of inflammatory disease

8 July 2018

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Tuning microenvironments: induction of regulatory T cells by dendritic cells

8 July 2018

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Effect of attenuation of Treg during BCG immunization on anti-mycobacterial Th1 responses and protection against Mycobacterium tuberculosis

8 July 2018

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Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

8 July 2018

1 reference

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8 July 2018

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Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor.

8 July 2018

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Full restoration of peripheral Foxp3+ regulatory T cell pool by radioresistant host cells in scurfy bone marrow chimeras

8 July 2018

1 reference

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Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells

8 July 2018

1 reference

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Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation

8 July 2018

1 reference

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Natural regulatory T cells: mechanisms of suppression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

8 July 2018

1 reference

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Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells

8 July 2018

1 reference

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The role of the transcription factor Foxp3 in the development of regulatory T cells

8 July 2018

1 reference

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Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27.

8 July 2018

1 reference

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

IL-27 suppresses CD28-mediated [correction of medicated] IL-2 production through suppressor of cytokine signaling 3.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-deficient mice display enhanced resistance to leishmania donovani infection but develop severe liver immunopathology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

IL-27 limits IL-2 production during Th1 differentiation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

A function for interleukin 2 in Foxp3-expressing regulatory T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

How do CD4+CD25+ regulatory T cells control autoimmunity?

8 July 2018

1 reference

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New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions

8 July 2018

1 reference

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Regulatory T cell lineage specification by the forkhead transcription factor foxp3

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Interleukin-2 is essential for CD4+CD25+ regulatory T cell function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Molecular phylogeny within type I cytokines and their cognate receptors

8 July 2018

1 reference

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Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Cellular and molecular characterization of the scurfy mouse mutant

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Control of B cell development by Ras-mediated activation of Raf.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

X-linked lymphoreticular disease in the scurfy (sf) mutant mouse

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

IL-27 inhibits the development of regulatory T cells via STAT3

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Interleukin-27 directly induces differentiation in hematopoietic stem cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Positive and negative regulation of the IL-27 receptor during lymphoid cell activation.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

IL-27 and IFN-αSignal via Stat1 and Stat3 and Induce T-Bet and IL-12Rβ2 in Naive T Cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119737

The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity

9 December 2018

1 reference

12 December 2020

Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice

1 reference

12 December 2020

Membranous glomerulonephritis development with Th2-type immune deviations in MRL/lpr mice deficient for IL-27 receptor (WSX-1)

1 reference

12 December 2020

Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system

1 reference

12 December 2020

CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

1 reference

12 December 2020

Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers

1 reference

12 December 2020

Host stem cells can selectively reconstitute missing lymphoid lineages in irradiation bone marrow chimeras

1 reference

12 December 2020

Selective availability of IL-2 is a major determinant controlling the production of CD4+CD25+Foxp3+ T regulatory cells

1 reference

12 December 2020

WSX-1 plays a significant role for the initiation of experimental autoimmune uveitis

1 reference

12 December 2020

IL-27 controls the development of inducible regulatory T cells and Th17 cells via differential effects on STAT1

1 reference

12 December 2020

Emerging challenges in regulatory T cell function and biology

1 reference

12 December 2020

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1004182

1 reference

6 August 2017

1 reference

6 August 2017

1 reference