(Q34996258)

English

The Stress-Inducible Immediate-Early Responsive Gene IEX-1 Is Activated in Cells Infected with Herpes Simplex Virus 1, but Several Viral Mechanisms, Including 3′ Degradation of Its RNA, Preclude Expression of the Gene

scientific article published on June 1, 2003

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Europe PubMed Central

PubMed publication ID

5 August 2017

The stress-inducible immediate-early responsive gene IEX-1 is activated in cells infected with herpes simplex virus 1, but several viral mechanisms, including 3' degradation of its RNA, preclude expression of the gene (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

The Stress-Inducible Immediate-Early Responsive Gene IEX-1 Is Activated in Cells Infected with Herpes Simplex Virus 1, but Several Viral Mechanisms, Including 3′ Degradation of Its RNA, Preclude Expression of the Gene (English)

1 reference

10.1128/JVI.77.11.6178-6187.2003

https://api.crossref.org/works/10.1128/JVI.77.11.6178-6187.2003

1 January 2024

1 reference

10.1128/JVI.77.11.6178-6187.2003

https://api.crossref.org/works/10.1128/JVI.77.11.6178-6187.2003

1 January 2024

1 reference

10.1128/JVI.77.11.6178-6187.2003

https://api.crossref.org/works/10.1128/JVI.77.11.6178-6187.2003

1 January 2024

Bernard Roizman

4

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Bernard Roizman

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Brunella Taddeo

1

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Brunella Taddeo

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

author name string

Audrey Esclatine

2

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Weiran Zhang

3

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Europe PubMed Central

PubMed publication ID

5 August 2017

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publication date

1 June 2003

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Europe PubMed Central

PubMed publication ID

5 August 2017

full work available at URL

https://jvi.asm.org/content/jvi/77/11/6178.full.pdf

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12743274

1 January 2024

https://europepmc.org/articles/PMC154982

online access status

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Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12743274

1 January 2024

https://europepmc.org/articles/PMC154982?pdf=render

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12743274

1 January 2024

https://doi.org/10.1128/jvi.77.11.6178-6187.2003

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12743274

1 January 2024

https://journals.asm.org/doi/pdf/10.1128/JVI.77.11.6178-6187.2003

1 reference

10.1128/JVI.77.11.6178-6187.2003

https://api.crossref.org/works/10.1128/JVI.77.11.6178-6187.2003

1 January 2024

Journal of Virology

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

77

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

6178-6187

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

The patterns of accumulation of cellular RNAs in cells infected with a wild-type and a mutant herpes simplex virus 1 lacking the virion host shutoff gene

1 reference

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8 July 2018

IEX-1: a new ERK substrate involved in both ERK survival activity and ERK activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

Of the three tegument proteins that package mRNA in herpes simplex virions, one (VP22) transports the mRNA to uninfected cells for expression prior to viral infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

IEX-1, an immediate early gene, increases the rate of apoptosis in keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

Expression of an immediate early gene, IEX-1, in human tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

Functional disruption of IEX-1 expression by concatemeric hammerhead ribozymes alters growth properties of 293 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

Replication of wild-type and mutant human cytomegalovirus in life-extended human diploid fibroblasts

1 reference

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8 July 2018

Herpes simplex virus ICP27 induces cytoplasmic accumulation of unspliced polyadenylated alpha-globin pre-mRNA in infected HeLa cells.

1 reference

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8 July 2018

The putative apoptosis inhibitor IEX-1L is a mutant nonspliced variant of p22(PRG1/IEX-1) and is not expressed in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

THE HIV-1 REV PROTEIN

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

A novel immediate early response gene, IEX-1, is induced by ultraviolet radiation in human keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

Regulation of a novel immediate early response gene, IEX-1, in keratinocytes by 1alpha,25-dihydroxyvitamin D3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

The promoter of human p22/PACAP response gene 1 (PRG1) contains functional binding sites for the p53 tumor suppressor and for NFkappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

Genomic organization, promoter cloning, and chromosomal localization of the Dif-2 gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

Shuttling of the herpes simplex virus type 1 regulatory protein ICP27 between the nucleus and cytoplasm mediates the expression of late proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

Differentiation of the shutoff of protein synthesis by virion host shutoff and mutant gamma (1)34.5 genes of herpes simplex virus 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

Assemblons: nuclear structures defined by aggregation of immature capsids and some tegument proteins of herpes simplex virus 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

Identification and characterization of a radiation-inducible glycosylated human early-response gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

Genomic structure, cDNA sequence, and expression of gly96, a growth factor-inducible immediate-early gene encoding a short-lived glycosylated protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

Early Virion-associated Suppression of Cellular Protein Synthesis by Herpes Simplex Virus is Accompanied by Inactivation of mRNA

1 reference

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8 July 2018

Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells

1 reference

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8 July 2018

The herpes simplex virus 1 RNA binding protein US11 is a virion component and associates with ribosomal 60S subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

8 July 2018

Activation of I kappa b kinase by herpes simplex virus type 1. A novel target for anti-herpetic therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

26 October 2018

Expression of the NF-kappa B target gene IEX-1 (p22/PRG1) does not prevent cell death but instead triggers apoptosis in Hela cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

26 October 2018

Respiratory syncytial virus infection induces expression of the anti-apoptosis gene IEX-1L in human respiratory epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=154982

26 October 2018

The virion host shutoff function of herpes simplex virus degrades the 5' end of a target mRNA before the 3' end.

1 reference

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26 October 2018

Herpes simplex type 1 induction of persistent NF-kappa B nuclear translocation increases the efficiency of virus replication

1 reference

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26 October 2018

Mullerian inhibiting substance inhibits breast cancer cell growth through an NFkappa B-mediated pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/12743274

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic and opposing regulation of the stress-responsive gene IEX-1 by p53, c-Myc, and multiple NF-kappaB/rel complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12743274

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human PACAP response gene 1 (p22/PRG1): proliferation-associated expression in pancreatic carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12743274

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer Research

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56

1498

publication date

1996

1 reference

10.1128/JVI.77.11.6178-6187.2003

https://api.crossref.org/works/10.1128/JVI.77.11.6178-6187.2003

1 January 2024

Identifiers

10.1128/JVI.77.11.6178-6187.2003

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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