(Q34994463)

5 August 2017

title

Natalizumab restores aberrant miRNA expression profile in multiple sclerosis and reveals a critical role for miR-20b (English)

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5 August 2017

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Hans-Peter Hartung

1 reference

5 August 2017

Bernd C Kieseier

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5 August 2017

Christina Backes

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5 August 2017

Orhan Aktas

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5 August 2017

Jens Ingwersen

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5 August 2017

Til Menge

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5 August 2017

Britta Wingerath

1 reference

5 August 2017

Derya Kaya

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5 August 2017

Jonas Graf

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5 August 2017

Tim Prozorovski

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5 August 2017

Andreas Keller

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5 August 2017

Markus Beier

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5 August 2017

Matthias Scheffler

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5 August 2017

Thomas Dehmel

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5 August 2017

Patrick Küry

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5 August 2017

publication date

5 December 2014

1 reference

Annals of clinical and translational neurology

5 August 2017

published in

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

43-55

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Natalizumab affects the T-cell receptor repertoire in patients with multiple sclerosis

5 August 2017

cites work

1 reference

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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miR-29ab1 deficiency identifies a negative feedback loop controlling Th1 bias that is dysregulated in multiple sclerosis

8 July 2018

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8 July 2018

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8 July 2018

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Glatiramer Acetate Treatment Normalizes Deregulated microRNA Expression in Relapsing Remitting Multiple Sclerosis

8 July 2018

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8 July 2018

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8 July 2018

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MicroRNAs miR-17 and miR-20a inhibit T cell activation genes and are under-expressed in MS whole blood

8 July 2018

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8 July 2018

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miR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer cells.

8 July 2018

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Altered expression of miR-17-5p in CD4+ lymphocytes of relapsing-remitting multiple sclerosis patients

8 July 2018

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MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47.

8 July 2018

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Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration.

8 July 2018

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MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis

8 July 2018

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Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls

8 July 2018

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Differential micro RNA expression in PBMC from multiple sclerosis patients

8 July 2018

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VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown

8 July 2018

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MicroRNAs: new regulators of immune cell development and function

8 July 2018

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miRiad roles for the miR-17-92 cluster in development and disease

8 July 2018

1 reference

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Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301674

GeneTrail--advanced gene set enrichment analysis

8 July 2018

1 reference

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Pharmacological properties, toxicology and scientific rationale for the use of natalizumab (Tysabri) in inflammatory diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301674

A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis

8 July 2018

1 reference

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Silencing of microRNAs in vivo with 'antagomirs'

8 July 2018

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Virtues and pitfalls of EAE for the development of therapies for multiple sclerosis

8 July 2018

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The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms

8 July 2018

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P-Match: transcription factor binding site search by combining patterns and weight matrices

8 July 2018

1 reference

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Autoimmune concepts of multiple sclerosis as a basis for selective immunotherapy: from pipe dreams to (therapeutic) pipelines

8 July 2018

1 reference

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VLA-4 integrin concentrates at the peripheral supramolecular activation complex of the immune synapse and drives T helper 1 responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301674

MicroRNAs: genomics, biogenesis, mechanism, and function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301674

8 July 2018

1 reference

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Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis.

8 July 2018

1 reference

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Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301674

Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301674

miR-20b suppresses Th17 differentiation and the pathogenesis of experimental autoimmune encephalomyelitis by targeting RORγt and STAT3.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301674

Decreased circulating miRNA levels in patients with primary progressive multiple sclerosis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301674

Differential microRNA expression in blood in multiple sclerosis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301674

Altered microRNA expression in B lymphocytes in multiple sclerosis: towards a better understanding of treatment effects.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301674

Modulation of adult hippocampal neurogenesis during myelin-directed autoimmune neuroinflammation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301674

Microfluidic-based enzymatic on-chip labeling of miRNAs

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301674

Natalizumab effects on immune cell responses in multiple sclerosis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301674

Differential effects of treatment with a small-molecule VLA-4 antagonist before and after onset of relapsing EAE.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301674

Natalizumab alters transcriptional expression profiles of blood cell subpopulations of multiple sclerosis patients

26 October 2018

1 reference

12 December 2020

Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity

1 reference

12 December 2020

T cell costimulation via the integrin VLA-4 inhibits the actin-dependent centralization of signaling microclusters containing the adaptor SLP-76

1 reference

12 December 2020

Additional efficacy endpoints from pivotal natalizumab trials in relapsing-remitting MS

1 reference

12 December 2020

Regulated microRNAs in the CSF of patients with multiple sclerosis: a case-control study

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12 December 2020

Sustained improvement in Expanded Disability Status Scale as a new efficacy measure of neurological change in multiple sclerosis: treatment effects with natalizumab in patients with relapsing multiple sclerosis

1 reference

12 December 2020

MicroRNA regulation in experimental autoimmune encephalomyelitis in mice and marmosets resembles regulation in human multiple sclerosis lesions

1 reference

12 December 2020

Immunology of multiple sclerosis

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12 December 2020

Natalizumab in clinical practice: managing the risks, enjoying the benefits

1 reference

12 December 2020

Identifiers

DOI

10.1002/ACN3.152

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5 August 2017

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5 August 2017

1 reference