(Q34978844)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686366%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

The role of MNK proteins and eIF4E phosphorylation in breast cancer cell proliferation and survival (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686366%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686366%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686366%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Matthew J Wheater

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686366%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

publication date

1 October 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686366%20AND%20SRC:MED&resulttype=core&format=json

Cancer Biology and Therapy

9 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686366%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686366%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686366%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

728-735

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686366%20AND%20SRC:MED&resulttype=core&format=json

Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation

9 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Phosphorylated eukaryotic translation initiation factor 4 (eIF4E) is elevated in human cancer tissues

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Overexpression of eukaryotic initiation factor 4E (eIF4E) and its clinical significance in lung adenocarcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Phosphorylation of eIF4E by MNKs supports protein synthesis, cell cycle progression and proliferation in prostate cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

The Mnks: MAP kinase-interacting kinases (MAP kinase signal-integrating kinases).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Targeting the eukaryotic translation initiation factor 4E for cancer therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Dissecting eIF4E action in tumorigenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

The selectivity of protein kinase inhibitors: a further update

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

MNK1 and EIF4E are downstream effectors of MEKs in the regulation of the nuclear export of HDM2 mRNA.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Controlling gene expression through RNA regulons: the role of the eukaryotic translation initiation factor eIF4E.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

eIF4E--from translation to transformation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Expression of the translation initiation factor eIF4E in the polyp-cancer sequence in the colon

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

eIF4E expression in tumors: its possible role in progression of malignancies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

The mRNA 5' cap-binding protein, eIF-4E, cooperates with v-myc or E1A in the transformation of primary rodent fibroblasts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

MNK, EIF4E and targeting translation for therapy.

8 July 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.10.7.12965

Detection of eIF4E gene amplification in breast cancer by competitive PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.10.7.12965

Eukaryotic initiation factor 4E overexpression in triple-negative breast cancer predicts a worse outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.10.7.12965

Overexpression of phospho-eIF4E is associated with survival through AKT pathway in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.10.7.12965

p53-independent activation of the hdm2-P2 promoter through multiple transcription factor response elements results in elevated hdm2 expression in estrogen receptor alpha-positive breast cancer cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093812

Competitive PCR to detect eIF4E gene amplification in head and neck cancer

26 October 2018

1 reference

12 December 2020

A prospective trial on initiation factor 4E (eIF4E) overexpression and cancer recurrence in node-positive breast cancer

1 reference

12 December 2020

Predictive value of eIF4E reduction after neoadjuvant therapy in breast cancer

1 reference

12 December 2020

eIF4E as a marker for cervical neoplasia

1 reference

12 December 2020

Determinants of MTT reduction in rat hepatocytes

1 reference

12 December 2020

The Mnks are novel components in the control of TNF alpha biosynthesis and phosphorylate and regulate hnRNP A1

1 reference

12 December 2020

Identifiers

DOI

10.4161/CBT.10.7.12965

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686366%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686366%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

20686366

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20686366%20AND%20SRC:MED&resulttype=core&format=json