(Q34975947)

5 August 2017

1 reference

title

The sodium iodide symporter: its pathophysiological and therapeutic implications (English)

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5 August 2017

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Christine Spitzweg

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5 August 2017

John C Morris

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5 August 2017

publication date

1 November 2002

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5 August 2017

published in

Clinical Endocrinology

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

559-574

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The sodium iodide symporter gene and its regulation by cytokines found in autoimmunity.

5 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Cloning of a functional promoter of the human sodium/iodide-symporter gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Transposition of the thyroid iodide uptake and organification system in nonthyroid tumor cells by adenoviral vector-mediated gene transfers

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Experimental targeted radioiodide therapy following transfection of the sodium iodide symporter gene: effect on clonogenicity in both two-and three-dimensional models.

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Iodide transport in the thyroid gland

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Hypothyroidism in transgenic mice expressing IFN-gamma in the thyroid

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Cloning and characterization of the thyroid iodide transporter

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

The cyclic AMP-mediated stimulation of cell proliferation

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Escape from the acute Wolff-Chaikoff effect is associated with a decrease in thyroid sodium/iodide symporter messenger ribonucleic acid and protein

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS)

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Congenital hypothyroidism caused by a mutation in the Na+/I- symporter

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Extracellular adenosine increases Na+/I- symporter gene expression in rat thyroid FRTL-5 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Ectopic expression of the thyroperoxidase gene augments radioiodide uptake and retention mediated by the sodium iodide symporter in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Analysis of human sodium/iodide symporter, thyroid transcription factor-1, and paired-box-protein-8 gene expression in benign thyroid diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Identification of antigenic domains on the human sodium-iodide symporter which are recognized by autoantibodies from patients with autoimmune thyroid disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Induction of follicle formation in long-term cultured normal human thyroid cells treated with thyrotropin stimulates iodide uptake but not sodium/iodide symporter messenger RNA and protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Retinoic acid induces sodium/iodide symporter gene expression and radioiodide uptake in the MCF-7 breast cancer cell line

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Pendred's syndrome: identification of the genetic defect a century after its recognition

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Characterization of the thyroid Na+/I- symporter with an anti-COOH terminus antibody

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

The Na+/I- symporter (NIS): recent advances.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Relationship between expression of the sodium/iodide symporter and 131I uptake in recurrent lesions of differentiated thyroid carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Correlation between 99mTc-pertechnetate uptakes and expressions of human sodium iodide symporter gene in breast tumor tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Expressions of human sodium iodide symporter mRNA in primary and metastatic papillary thyroid carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Cloning of the mouse sodium iodide symporter and its expression in the mammary gland and other tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Cloning of the mouse sodium iodide symporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Mutations in the sodium/iodide symporter (NIS) gene as a cause for iodide transport defects and congenital hypothyroidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Hypothyroidism in a Brazilian Kindred Due to Iodide Trapping Defect Caused by a Homozygous Mutation in the Sodium/Iodide Symporter Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Congenital hypothyroidism due to mutations in the sodium/iodide symporter. Identification of a nonsense mutation producing a downstream cryptic 3' splice site

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Post-transcriptional regulation of the sodium/iodide symporter by thyrotropin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Expression of the sodium iodide symporter and thyroglobulin genes are reduced in papillary thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Increased expression of the sodium/iodide symporter in papillary thyroid carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Retinoic acid increases sodium/iodide symporter mRNA levels in human thyroid cancer cell lines and suppresses expression of functional symporter in nontransformed FRTL-5 rat thyroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

The Pendred syndrome gene encodes a chloride-iodide transport protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Iodide Uptake and Experimental 131I Therapy in Transplanted Undifferentiated Thyroid Cancer Cells Expressing the Na+/I− Symporter Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Cloning of the human sodium lodide symporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Expression, exon-intron organization, and chromosome mapping of the human sodium iodide symporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Iodide kinetics and experimental (131)I therapy in a xenotransplanted human sodium-iodide symporter-transfected human follicular thyroid carcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Regulation of sodium iodide symporter gene expression in FRTL-5 rat thyroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Expression of the sodium iodide symporter in human kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Follicular thyroglobulin suppresses iodide uptake by suppressing expression of the sodium/iodide symporter gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Autoantibodies from patients with autoimmune thyroid disease do not interfere with the activity of the human iodide symporter gene stably transfected in CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Promoter Characterization of the Rat Na+/I−Symporter Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Iodide symporter gene expression in normal and transformed rat thyroid cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Cloning of the human sodium-iodide symporter promoter and characterization in a differentiated human thyroid cell line, KAT-50

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

TRANSPORT OF IODIDE AND OTHER ANIONS IN THE THYROID GLAND.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

A GC box in the human sodium iodide symporter gene promoter is essential for full activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Reestablishment of in vitro and in vivo iodide uptake by transfection of the human sodium iodide symporter (hNIS) in a hNIS defective human thyroid carcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Regulation and tissue distribution of the human sodium iodide symporter gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Monoclonal antibodies against the human sodium iodide symporter: utility for immunocytochemistry of thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Immunohistochemical analysis of sodium iodide symporter expression in metastatic differentiated thyroid cancer: correlation with radioiodine uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Rhenium-188 as an alternative to Iodine-131 for treatment of breast tumors expressing the sodium/iodide symporter (NIS)

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Autoantibody against thyroid iodide transporter in the sera from patients with Hashimoto's thyroiditis possesses iodide transport inhibitory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Autoantibody against Na+/I- symporter in the sera of patients with autoimmune thyroid disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Suppressive effect of iodine on DMBA-induced breast tumor growth in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Transforming Growth Factor-β1 Suppresses Thyrotropin-Induced Na+/I- Symporter Messenger RNA and Protein Levels in FRTL-5 Rat Thyroid Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

In vivo expression and function of the sodium iodide symporter following gene transfer in the MATLyLu rat model of metastatic prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Expression of sodium iodide symporter in benign and malignant human thyroid tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Binding of Immunoglobulin G from Patients with Autoimmune Thyroid Disease to Rat Sodium-Iodide Symporter Peptides: Evidence for the Iodide Transporter as an Autoantigen*

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Identification of the thyroid Na+/I- cotransporter as a potential autoantigen in thyroid autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Characteristics of the Prolactin Stimulation of Iodide Uptake into Mouse Mammary Gland Explants

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Effect of prolactin on sodium iodide symporter expression in mouse mammary gland explants

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Sodium/iodide symporter (NIS) and pendrin are expressed differently in hot and cold nodules of thyroid toxic multinodular goiter

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Absence of sodium/iodide symporter gene mutations in differentiated human thyroid carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Redifferentiation therapy with retinoids: therapeutic option for advanced follicular and papillary thyroid carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Genetic basis of congenital hypothyroidism: abnormalities in the TSHbeta gene, the PIT1 gene, and the NIS gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

The mammary gland iodide transporter is expressed during lactation and in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Benign nonfunctioning thyroid adenomas are characterized by a defective targeting to cell membrane or a reduced expression of the sodium iodide symporter protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Moderate doses of iodide in vivo inhibit cell proliferation and the expression of thyroperoxidase and Na+/I− symporter mRNAs in dog thyroid

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

Metastatic thyroid carcinoma in man concentrating iodine without organification

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

The temporary nature of the inhibitory action of excess iodine on organic iodine synthesis in the normal thyroid

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2002.01640.X

10.1046/J.1365-2265.2002.01640.X

21 January 2018

Identifiers

DOI

1 reference

5 August 2017

1 reference