(Q34744444)

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Pemetrexed induced thymidylate synthase inhibition in non-small cell lung cancer patients: a pilot study with 3'-deoxy-3'-[¹⁸F]fluorothymidine positron emission tomography

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Europe PubMed Central

PubMed publication ID

4 August 2017

Pemetrexed induced thymidylate synthase inhibition in non-small cell lung cancer patients: a pilot study with 3'-deoxy-3'-[¹⁸F]fluorothymidine positron emission tomography (English)

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Europe PubMed Central

PubMed publication ID

4 August 2017

non-small-cell lung carcinoma

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Elisa Giovannetti

object named as

Elisa Giovannetti

5

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Erik Thunnissen

object named as

Erik Thunnissen

8

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Ronald Boellaard

object named as

Ronald Boellaard

3

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Otto S Hoekstra

9

object named as

Otto S Hoekstra

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

author name string

Virginie Frings

1

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Europe PubMed Central

PubMed publication ID

4 August 2017

Astrid A M van der Veldt

2

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Europe PubMed Central

PubMed publication ID

4 August 2017

Gerarda J M Herder

4

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Richard Honeywell

6

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Godefridus J Peters

7

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Europe PubMed Central

PubMed publication ID

4 August 2017

Egbert F Smit

10

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Europe PubMed Central

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4 August 2017

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publication date

24 May 2013

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Europe PubMed Central

PubMed publication ID

4 August 2017

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Europe PubMed Central

PubMed publication ID

4 August 2017

8

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Europe PubMed Central

PubMed publication ID

4 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

e63705

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Europe PubMed Central

PubMed publication ID

4 August 2017

copyright license

Creative Commons Attribution 4.0 International

24 May 2013

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April 2022 Public Data File from Crossref

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0 references

[(18)F]FLT: an imaging biomarker of tumour proliferation for assessment of tumour response to treatment.

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The presence of three repeats in the 5' UTR region of thymidylate synthase (TS) is associated with increased TS mRNA expression in cultured human cancer cell lines in vitro

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Thymidylate synthase inhibitors for non-small cell lung cancer

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Novel therapeutic targets in non-small cell lung cancer

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Non-small-cell lung cancer.

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Thymidylate synthase as a determinant of pemetrexed sensitivity in non-small cell lung cancer

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Altered tissue 3'-deoxy-3'-[18F]fluorothymidine pharmacokinetics in human breast cancer following capecitabine treatment detected by positron emission tomography

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Reproducibility of quantitative 18F-3'-deoxy-3'-fluorothymidine measurements using positron emission tomography

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Imaging pharmacodynamics of the alpha-folate receptor-targeted thymidylate synthase inhibitor BGC 945.

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7 July 2018

The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours

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Methylenetetrahydrofolate reductase (MTHFR) C677T and thymidylate synthase promoter (TSER) polymorphisms in Indonesian children with and without leukemia

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The determination of gemcitabine and 2'-deoxycytidine in human plasma and tissue by APCI tandem mass spectrometry

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Redistribution of nucleoside transporters to the cell membrane provides a novel approach for imaging thymidylate synthase inhibition by positron emission tomography

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Prognostic significance of the polymorphisms in thymidylate synthase and methylenetetrahydrofolate reductase gene in lung cancer.

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Pemetrexed: a multitargeted antifolate

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Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism

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Phase II trial of pemetrexed disodium (ALIMTA, LY231514) in chemotherapy-naïve patients with advanced non-small-cell lung cancer

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Multitargeted antifolate LY231514 as first-line chemotherapy for patients with advanced non-small-cell lung cancer: A phase II study. National Cancer Institute of Canada Clinical Trials Group

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Performance evaluation of a whole-body PET scanner using the NEMA protocol. National Electrical Manufacturers Association

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Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data

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2-[11C]thymidine positron emission tomography as an indicator of thymidylate synthase inhibition in patients treated with AG337.

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A new look at the statistical model identification

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In vivo validation of 3'deoxy-3'-[(18)F]fluorothymidine ([(18)F]FLT) as a proliferation imaging tracer in humans: correlation of [(18)F]FLT uptake by positron emission tomography with Ki-67 immunohistochemistry and flow cytometry in human lung tumor

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Patterns of elevation of plasma 2'-deoxyuridine, a surrogate marker of thymidylate synthase (TS) inhibition, after administration of two different schedules of 5-fluorouracil and the specific TS inhibitors raltitrexed (Tomudex) and ZD9331.

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Thymidylate synthase expression in patients with colorectal carcinoma using a polyclonal thymidylate synthase antibody in comparison to the TS 106 monoclonal antibody

1 reference

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Identifiers

10.1371/JOURNAL.PONE.0063705

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

2013PLoSO...863705F

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

ResearchGate publication ID

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