(Q34625607)

25446896

3 August 2017

title

Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells (English)

1 reference

3 August 2017

0 references

1 reference

1 reference

Debbie Chang-Strachan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Vivien Chan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Alexander Rosenbusch

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Christine M T Ho

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Nancy Pryer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Dylan Daniel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

E Shelley Hwang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Lisa M Coussens

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

publication date

16 October 2014

1 reference

3 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

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10 June 2020

issue

1 reference

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10 June 2020

page(s)

623-637

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446896%20AND%20SRC:MED&resulttype=core&format=json

Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy

10 June 2020

cites work

1 reference

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CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8(+) T cells

7 July 2018

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Therapeutic use of dendritic cells to promote the extranodal priming of anti-tumor immunity

7 July 2018

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Inhibition of CSF-1 receptor improves the antitumor efficacy of adoptive cell transfer immunotherapy

7 July 2018

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Interferon-dependent IL-10 production by Tregs limits tumor Th17 inflammation

7 July 2018

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CSF-1R inhibition alters macrophage polarization and blocks glioma progression

7 July 2018

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Tissues in different anatomical sites can sculpt and vary the tumor microenvironment to affect responses to therapy

7 July 2018

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A phase I study of an agonist CD40 monoclonal antibody (CP-870,893) in combination with gemcitabine in patients with advanced pancreatic ductal adenocarcinoma

7 July 2018

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Adenomatous polyps are driven by microbe-instigated focal inflammation and are controlled by IL-10-producing T cells

7 July 2018

1 reference

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Oncology meets immunology: the cancer-immunity cycle

7 July 2018

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CD4⁺ follicular helper T cell infiltration predicts breast cancer survival

7 July 2018

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Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells

7 July 2018

1 reference

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Immunogenic cell death in cancer therapy

7 July 2018

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Comprehensive molecular portraits of human breast tumours

7 July 2018

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IL-10 directly activates and expands tumor-resident CD8(+) T cells without de novo infiltration from secondary lymphoid organs

7 July 2018

1 reference

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Differential macrophage programming in the tumor microenvironment

7 July 2018

1 reference

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IL-10 elicits IFNγ-dependent tumor immune surveillance.

7 July 2018

1 reference

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Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Leukocyte composition of human breast cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Increased serum enzyme levels associated with kupffer cell reduction with no signs of hepatic or skeletal muscle injury

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Macrophage Expression of Hypoxia-Inducible Factor-1α Suppresses T-Cell Function and Promotes Tumor Progression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Evaluation of a 30-gene paclitaxel, fluorouracil, doxorubicin, and cyclophosphamide chemotherapy response predictor in a multicenter randomized trial in breast cancer.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

The regulation of IL-10 production by immune cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Trophic macrophages in development and disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Myeloid-derived suppressor cells as regulators of the immune system

7 July 2018

1 reference

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Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis

7 July 2018

1 reference

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Strategies for use of IL-10 or its antagonists in human disease

7 July 2018

1 reference

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B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

7 July 2018

1 reference

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Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection.

7 July 2018

1 reference

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Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Interleukin-12 and the regulation of innate resistance and adaptive immunity

7 July 2018

1 reference

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Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

7 July 2018

1 reference

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Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody

7 July 2018

1 reference

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The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies

7 July 2018

1 reference

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Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Interleukin-10 and the interleukin-10 receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Expression of IL-10 receptors on epithelial cells from the murine small and large intestine.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor alpha production

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

IL-10: a novel cytotoxic T cell differentiation factor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Post-transcriptional regulation of adapter molecules by IL-10 inhibits TLR-mediated activation of antigen-presenting cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Identification of an integrated SV40 T/t-antigen cancer signature in aggressive human breast, prostate, and lung carcinomas with poor prognosis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Modulation of CSF-1-regulated post-natal development with anti-CSF-1 antibody.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

L-arginine consumption by macrophages modulates the expression of CD3 zeta chain in T lymphocytes

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254570

Chemotherapy response of spontaneous mammary tumors is independent of the adaptive immune system

26 October 2018

1 reference

12 December 2020

Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes

1 reference

12 December 2020

Inhibitory and stimulatory effects of IL-10 on human CD8+ T cells

1 reference

12 December 2020

IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages

1 reference

12 December 2020

IL-10 controls ultraviolet-induced carcinogenesis in mice

1 reference

12 December 2020

Tumor-induced interleukin 10 suppresses the ability of splenic dendritic cells to stimulate CD4 and CD8 T-cell responses

1 reference

12 December 2020

Interleukin-10-deficient mice and inflammatory bowel disease associated cancer development

1 reference

12 December 2020

10.1016/J.CCELL.2014.09.006

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446896%20AND%20SRC:MED&resulttype=core&format=json

release_zso7ntk57re6njwguuh4iz5qvm

10 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zso7ntk57re6njwguuh4iz5qvm

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446896%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

25446896

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446896%20AND%20SRC:MED&resulttype=core&format=json