(Q34604140)

3 August 2017

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title

Rho-glucosylating Clostridium difficile toxins A and B: new insights into structure and function (English)

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3 August 2017

main subject

Clostridium difficile

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Klaus Aktories

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author name string

Thomas Jank

series ordinal

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3 August 2017

Torsten Giesemann

series ordinal

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3 August 2017

publication date

19 January 2007

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3 August 2017

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

15R-22R

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Bacterial cytotoxins: targeting eukaryotic switches

3 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Low pH-induced formation of ion channels by clostridium difficile toxin B in target cells

21 January 2018

1 reference

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Clinical practice. Antibiotic-associated diarrhea

21 January 2018

1 reference

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Pathogenesis of Clostridium difficile infection

21 January 2018

1 reference

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Structures and mechanisms of glycosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Rho and Rac take center stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Microbial toxins and the glycosylation of rho family GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Involvement of a conserved tryptophan residue in the UDP-glucose binding of large clostridial cytotoxin glycosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

A common motif of eukaryotic glycosyltransferases is essential for the enzyme activity of large clostridial cytotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Structure of the nucleotide-diphospho-sugar transferase, SpsA from Bacillus subtilis, in native and nucleotide-complexed forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

A novel cytotoxin from Clostridium difficile serogroup F is a functional hybrid between two other large clostridial cytotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

An evolving hierarchical family classification for glycosyltransferases

21 January 2018

1 reference

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Sweet secrets of synthesis.

21 January 2018

1 reference

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Rho GTPases in cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

A novel solenoid fold in the cell wall anchoring domain of the pneumococcal virulence factor LytA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Internalization of Clostridium difficile cytotoxin into cultured human lung fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Bovine alpha1,3-galactosyltransferase catalytic domain structure and its relationship with ABO histo-blood group and glycosphingolipid glycosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Monoglucosylation of RhoA at threonine 37 blocks cytosol-membrane cycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Clostridium difficile toxin A induces expression of the stress-induced early gene product RhoB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Glucosylation of Ras by Clostridium sordellii lethal toxin: consequences for effector loop conformations observed by NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Crystal structure of the autocatalytic initiator of glycogen biosynthesis, glycogenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Cholesterol-dependent pore formation of Clostridium difficile toxin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Carbohydrate recognition by Clostridium difficile toxin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

The toxigenic element of Clostridium difficile strain VPI 10463.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Cellular internalisation of Clostridium difficile toxin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Functional consequences of monoglucosylation of Ha-Ras at effector domain amino acid threonine 35.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Crystal structure of receptor-binding C-terminal repeats from Clostridium difficile toxin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Transcription analysis of the genes tcdA-E of the pathogenicity locus of Clostridium difficile

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Change of the donor substrate specificity of Clostridium difficile toxin B by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Inactivation of Ras by Clostridium sordellii lethal toxin-catalyzed glucosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Glucosylation of Rho proteins by Clostridium difficile toxin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Molecular basis of evolutionary loss of the alpha 1,3-galactosyltransferase gene in higher primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Regulation of toxin synthesis in Clostridium difficile by an alternative RNA polymerase sigma factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

An epidemic, toxin gene-variant strain of Clostridium difficile

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

A phosphatidylserine-binding site in the cytosolic fragment of Clostridium sordellii lethal toxin facilitates glucosylation of membrane-bound Rac and is required for cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Crystal structure of the retaining galactosyltransferase LgtC from Neisseria meningitidis in complex with donor and acceptor sugar analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Cellular uptake of Clostridium difficile toxin B. Translocation of the N-terminal catalytic domain into the cytosol of eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Ras, Rap, and Rac small GTP-binding proteins are targets for Clostridium sordellii lethal toxin glucosylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

pH-induced conformational changes in Clostridium difficile toxin B

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Structural basis for the function of Clostridium difficile toxin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Characterization of the cleavage site and function of resulting cleavage fragments after limited proteolysis of Clostridium difficile toxin B (TcdB) by host cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Large clostridial cytotoxins: cellular biology of Rho/Ras-glucosylating toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Clostridium novyi alpha-toxin-catalyzed incorporation of GlcNAc into Rho subfamily proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Polymeric IgA is superior to monomeric IgA and IgG carrying the same variable domain in preventing Clostridium difficile toxin A damaging of T84 monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Purification and characterisation of toxin B from a strain of Clostridium difficile that does not produce toxin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Glycosyltransferase structure and mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

The guanine nucleotide-binding switch in three dimensions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Large clostridial cytotoxins--a family of glycosyltransferases modifying small GTP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Clostridium difficile toxin A carries a C-terminal repetitive structure homologous to the carbohydrate binding region of streptococcal glycosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

Clostridium difficile toxins: mechanism of action and role in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWM004

21 January 2018

Identifiers

DOI

10.1093/GLYCOB/CWM004

1 reference

release_xyvsms276fgzhmaaawlvnx5mhq

3 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xyvsms276fgzhmaaawlvnx5mhq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference