(Q34657095)

3 August 2017

title

Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosis (English)

1 reference

3 August 2017

Florian C Kurschus

1 reference

3 August 2017

Edward Fellows

series ordinal

1 reference

3 August 2017

Elisabeth Stegmann

series ordinal

1 reference

3 August 2017

Dieter E Jenne

series ordinal

1 reference

3 August 2017

language of work or name

English

0 references

publication date

4 September 2008

1 reference

Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

1 reference

inferred from page(s)

published in

1 reference

3 August 2017

volume

105

1 reference

3 August 2017

1 reference

3 August 2017

page(s)

13799-13804

1 reference

Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

A common fold mediates vertebrate defense and bacterial attack

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Apoptosis induced by the lymphocyte effector molecule perforin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Delivering the kiss of death: progress on understanding how perforin works

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Perforin-mediated target-cell death and immune homeostasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Extracellular granzymes: current perspectives

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Granule-mediated killing by granzyme B and perforin requires a mannose 6-phosphate receptor and is augmented by cell surface heparan sulfate

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Targeted induction of apoptosis by chimeric granzyme B fusion proteins carrying antibody and growth factor domains for cell recognition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Cationic sites on granzyme B contribute to cytotoxicity by promoting its uptake into target cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Selective chemical functional probes of granzymes A and B reveal granzyme B is a major effector of natural killer cell-mediated lysis of target cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Structural basis of pore formation by the bacterial toxin pneumolysin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Granzyme B binds to target cells mostly by charge and must be added at the same time as perforin to trigger apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Interaction of the nuclear localizing cytolytic granule serine protease granzyme B with importin alpha or beta: modulation by the serpin inhibitor PI-9.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Membrane receptors are not required to deliver granzyme B during killer cell attack

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Killing of target cells by redirected granzyme B in the absence of perforin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Targeted delivery of human pro-apoptotic enzymes to tumor cells: In vitro studies describing a novel class of recombinant highly cytotoxic agents.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Perforin and the granule exocytosis cytotoxicity pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Endocytosing the death sentence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Calculation of hydrodynamic properties of globular proteins from their atomic-level structure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

The architecture of complement component C9 and poly(C9).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

The ninth component of complement and the pore-forming protein (perforin 1) from cytotoxic T cells: structural, immunological, and functional similarities

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Cytotoxic granules from killer cells: specificity of granules and insertion of channels of defined size into target membranes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Functional size of complement and perforin pores compared by confocal laser scanning microscopy and fluorescence microphotolysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544534

Ultrastructural analysis of the membrane insertion of domain 3 of streptolysin O.

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0801724105

Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0801724105

A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0801724105

Assembly of two types of tubules with putative cytolytic function by cloned natural killer cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18772390

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Isolation of a lytic, pore-forming protein (perforin) from cytolytic T-lymphocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18772390

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Concanamycin A, a powerful tool for characterization and estimation of contribution of perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18772390

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0801724105

1 reference

3 August 2017

0 references

1 reference

3 August 2017

1 reference