(Q34640994)

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Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis

scientific article published on 26 March 2013

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Europe PubMed Central

PubMed publication ID

3 August 2017

Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

amyotrophic lateral sclerosis

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Robert J Ferrante

12

object named as

Robert J Ferrante

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Europe PubMed Central

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3 August 2017

author name string

Yi Zhang

1

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Europe PubMed Central

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3 August 2017

Anna Cook

2

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3 August 2017

Jinho Kim

3

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Europe PubMed Central

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3 August 2017

Sergei V Baranov

4

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3 August 2017

Jiying Jiang

5

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3 August 2017

Karen Smith

6

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3 August 2017

Kerry Cormier

7

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3 August 2017

Erik Bennett

8

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3 August 2017

Robert P Browser

9

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3 August 2017

Arthur L Day

10

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3 August 2017

Diane L Carlisle

11

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Europe PubMed Central

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3 August 2017

Xin Wang

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Robert M Friedlander

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publication date

26 March 2013

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3 August 2017

Neurobiology of Disease

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3 August 2017

55

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3 August 2017

26-35

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Europe PubMed Central

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3 August 2017

The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Dipyrone inhibits neuronal cell death and diminishes hypoxic/ischemic brain injury

1 reference

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7 July 2018

Microglia in ALS: the good, the bad, and the resting

1 reference

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7 July 2018

Mitochondrial dysfunction in amyotrophic lateral sclerosis.

1 reference

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7 July 2018

Methazolamide and melatonin inhibit mitochondrial cytochrome C release and are neuroprotective in experimental models of ischemic injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Inhibitors of cytochrome c release with therapeutic potential for Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Cytoprotective effects of melatonin on C6 astroglial cells exposed to glutamate excitotoxicity and oxidative stress

1 reference

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7 July 2018

Nortriptyline delays disease onset in models of chronic neurodegeneration

1 reference

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7 July 2018

Reduced oxidative damage in ALS by high-dose enteral melatonin treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Mitochondria in amyotrophic lateral sclerosis: a trigger and a target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Antioxidative Protection by Melatonin: Multiplicity of Mechanisms from Radical Detoxification to Radical Avoidance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Cytochrome C release from CNS mitochondria and potential for clinical intervention in apoptosis-mediated CNS diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Reduced hippocampal MT2 melatonin receptor expression in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Regulation of antioxidant enzymes: a significant role for melatonin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Apoptosis and caspases in neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Inflammatory processes in amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Therapies in amyotrophic lateral sclerosis-beyond riluzole.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Apoptosis in amyotrophic lateral sclerosis: a review of the evidence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Cytoskeletal abnormalities in amyotrophic lateral sclerosis: beneficial or detrimental effects?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Mechanisms for neuronal degeneration in amyotrophic lateral sclerosis and in models of motor neuron death (Review).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Practice parameter: the care of the patient with amyotrophic lateral sclerosis (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology: ALS Practice Parameters Task Force

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Increase of glial fibrillary acidic protein fragments in the spinal cord of motor neuron degeneration mutant mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Evidence of Increased Oxidative Damage in Both Sporadic and Familial Amyotrophic Lateral Sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

7 July 2018

Decreased MT1 and MT2 melatonin receptor expression in extrapineal tissues of the rat during physiological aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

26 October 2018

Favorable effects of a prolonged treatment with melatonin on the level of oxidative damage and neurodegeneration in senescence-accelerated mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

26 October 2018

Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

26 October 2018

Expression of membrane and nuclear melatonin receptors in mouse peripheral organs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

26 October 2018

Additive neuroprotective effects of minocycline with creatine in a mouse model of ALS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

26 October 2018

Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

26 October 2018

Melatonin as a candidate compound for neuroprotection in amyotrophic lateral sclerosis (ALS): high tolerability of daily oral melatonin administration in ALS patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

26 October 2018

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

26 October 2018

Cerebrovascular melatonin MT1-receptor alterations in patients with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652329

26 October 2018

Live imaging of amyotrophic lateral sclerosis pathogenesis: disease onset is characterized by marked induction of GFAP in Schwann cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23537713

12 December 2020

based on heuristic

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Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

1 reference

https://pubmed.ncbi.nlm.nih.gov/23537713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23537713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of neurophilin ligands on motor units in mice with SOD1 ALS mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/23537713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Instrumental activation of bid by caspase-1 in a transgenic mouse model of ALS

1 reference

https://pubmed.ncbi.nlm.nih.gov/23537713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessing disease onset and progression in the SOD1 mouse model of ALS

1 reference

https://pubmed.ncbi.nlm.nih.gov/23537713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sexual differences in onset of disease and response to exercise in a transgenic model of ALS

1 reference

https://pubmed.ncbi.nlm.nih.gov/23537713

12 December 2020

based on heuristic

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A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/23537713

12 December 2020

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The melatonin receptor in the human brain: cloning experiments and distribution studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/23537713

12 December 2020

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Inhibition of ICE slows ALS in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23537713

12 December 2020

based on heuristic

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Bcl-2: Prolonging Life in a Transgenic Mouse Model of Familial Amyotrophic Lateral Sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23537713

12 December 2020

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Identifiers

10.1016/J.NBD.2013.03.008

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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