(Q34535652)

2 August 2017

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title

Telomere dysfunction: multiple paths to the same end. (English)

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2 August 2017

Lea Harrington

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2 August 2017

Murray O Robinson

series ordinal

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2 August 2017

language of work or name

English

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publication date

1 January 2002

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2 August 2017

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

592-597

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Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Reconstitution of human telomerase activity in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Functional characterization and developmental regulation of mouse telomerase RNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

A human telomeric protein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

The hTERTalpha splice variant is a dominant negative inhibitor of telomerase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Evolution of functions within the p53/p63/p73 family.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Telomere maintenance by recombination in human cells.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Telomerase activity and telomere length in pediatric patients with malignancies undergoing chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Telomere length regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Mammalian telomeres end in a large duplex loop

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Inhibition of telomerase is related to the life span and tumorigenicity of human prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Creation of human tumour cells with defined genetic elements

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Inhibition of telomerase limits the growth of human cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Telomere loss: mitotic clock or genetic time bomb?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Human telomerase contains evolutionarily conserved catalytic and structural subunits

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Telomere reduction in human colorectal carcinoma and with ageing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Recombination in telomere-length maintenance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Essential role of mouse telomerase in highly proliferative organs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Telomere dysfunction alters the chemotherapeutic profile of transformed cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Reverse transcriptase motifs in the catalytic subunit of telomerase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Reprogramming of Telomerase by Expression of Mutant Telomerase RNA Template in Human Cells Leads to Altered Telomeres That Correlate with Reduced Cell Viability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Telomere dysfunction and evolution of intestinal carcinoma in mice and humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

A survey of telomerase activity in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

TRF2 Protects Human Telomeres from End-to-End Fusions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

An alternate splicing variant of the human telomerase catalytic subunit inhibits telomerase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205084

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1126/SCIENCE.279.5349.349

Identifiers

DOI

10.1038/SJ.ONC.1205084

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Dimensions Publication ID

2 August 2017

1021095073

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