(Q34527422)

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Dose ranging pharmacokinetic trial of high-dose alicaforsen (intercellular adhesion molecule-1 antisense oligodeoxynucleotide) (ISIS 2302) in active Crohn's disease

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Europe PubMed Central

PubMed publication ID

2 August 2017

Dose ranging pharmacokinetic trial of high-dose alicaforsen (intercellular adhesion molecule-1 antisense oligodeoxynucleotide) (ISIS 2302) in active Crohn's disease (English)

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Europe PubMed Central

PubMed publication ID

2 August 2017

Crohn's disease

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pharmacokinetics

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based on heuristic

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Yacyshyn BR

1

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Europe PubMed Central

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2 August 2017

Barish C

2

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Europe PubMed Central

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2 August 2017

Goff J

3

1 reference

Europe PubMed Central

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2 August 2017

Dalke D

4

1 reference

Europe PubMed Central

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2 August 2017

Gaspari M

5

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Europe PubMed Central

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2 August 2017

Yu R

6

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Europe PubMed Central

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2 August 2017

Tami J

7

1 reference

Europe PubMed Central

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2 August 2017

Dorr FA

8

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Europe PubMed Central

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2 August 2017

Sewell KL

9

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2 August 2017

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publication date

1 October 2002

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2 August 2017

Alimentary Pharmacology & Therapeutics

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2 August 2017

16

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Europe PubMed Central

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2 August 2017

10

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Europe PubMed Central

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2 August 2017

1761-1770

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Europe PubMed Central

PubMed publication ID

2 August 2017

ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18)

1 reference

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Neutrophil induced oxidative injury of cardiac myocytes. A compartmented system requiring CD11b/CD18-ICAM-1 adherence

1 reference

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21 January 2018

Regulation of adhesion molecule expression by human synovial microvascular endothelial cells in vitro.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2036.2002.01341.X

21 January 2018

Beta2 integrin/ICAM expression in Crohn's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2036.2002.01341.X

21 January 2018

Comparative studies of the colonic in situ expression of intercellular adhesion molecules (ICAM-1, -2, and -3), beta2 integrins (LFA-1, Mac-1, and p150,95), and PECAM-1 in ulcerative colitis and Crohn's disease

1 reference

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21 January 2018

Expression of lymphocyte-endothelial receptor-ligand pairs, alpha4beta7/MAdCAM-1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease

1 reference

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21 January 2018

Regulation of ICAM-1-mediated fibroblast-T cell reciprocal interaction: implications for modulation of gut inflammation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2036.2002.01341.X

21 January 2018

T-Cell Function and Migration — Two Sides of the Same Coin

1 reference

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21 January 2018

Changed colonic profile of P-selectin, platelet-endothelial cell adhesion molecule-1 (PECAM-1), intercellular adhesion molecule-1 (ICAM-1), ICAM-2, and ICAM-3 in inflammatory bowel disease

1 reference

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21 January 2018

Novel mechanisms for antisense-mediated regulation of gene expression

1 reference

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21 January 2018

Correlation of toxicity and pharmacokinetic properties of a phosphorothioate oligonucleotide designed to inhibit ICAM-1.

1 reference

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21 January 2018

Enhanced metastatic ability of TNF-alpha-treated malignant melanoma cells is reduced by intercellular adhesion molecule-1 (ICAM-1, CD54) antisense oligonucleotides

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2036.2002.01341.X

21 January 2018

Role of the intercellular adhesion molecule-1(ICAM-1) in endotoxin-induced pneumonia evaluated using ICAM-1 antisense oligonucleotides, anti-ICAM-1 monoclonal antibodies, and ICAM-1 mutant mice

1 reference

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21 January 2018

A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2036.2002.01341.X

21 January 2018

Quantitation of phosphorothioate oligonucleotides in human plasma

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2036.2002.01341.X

21 January 2018

Development of an ultrasensitive noncompetitive hybridization-ligation enzyme-linked immunosorbent assay for the determination of phosphorothioate oligodeoxynucleotide in plasma

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2036.2002.01341.X

21 January 2018

Phosphorothioate oligonucleotides inhibit the intrinsic tenase complex by an allosteric mechanism

1 reference

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21 January 2018

Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis

1 reference

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21 January 2018

Functional evidence that intercellular adhesion molecule-1 (icam-1) is a ligand for lfa-1d-ependent adhesion in t cell-mediated cytotoxicity

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2036.2002.01341.X

21 January 2018

Identifiers

10.1046/J.1365-2036.2002.01341.X

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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