(Q34526433)

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Resurgent current and voltage sensor trapping enhanced activation by a beta-scorpion toxin solely in Nav1.6 channel. Significance in mice Purkinje neurons.

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21 January 2020

Resurgent current and voltage sensor trapping enhanced activation by a beta-scorpion toxin solely in Nav1.6 channel. Significance in mice Purkinje neurons (English)

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21 January 2020

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Emanuele Schiavon

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21 January 2020

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21 January 2020

Lourival Possani Postay

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Lourival D Possani

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21 January 2020

Rita Restano Cassulini

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Rita Restano Cassulini

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21 January 2020

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Enzo Wanke

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21 January 2020

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Georgina Gurrola

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Georgina Gurrola

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21 January 2020

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Tiziana Sacco

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21 January 2020

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15 May 2006

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21 January 2020

Journal of Biological Chemistry

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21 January 2020

281

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21 January 2020

29

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21 January 2020

20326-20337

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21 January 2020

From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Voltage sensors in domains III and IV, but not I and II, are immobilized by Na+ channel fast inactivation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Voltage sensor-trapping: enhanced activation of sodium channels by beta-scorpion toxin bound to the S3-S4 loop in domain II.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Molecular mechanisms of neurotoxin action on voltage-gated sodium channels.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Neutralization of gating charges in domain II of the sodium channel alpha subunit enhances voltage-sensor trapping by a beta-scorpion toxin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Modification of sodium channel gating in frog myelinated nerve fibres by Centruroides sculpturatus scorpion venom

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Effect of toxins isolated from the venom of the scorpion Centruroides sculpturatus on the Na currents of the node of Ranvier.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Altered Subthreshold Sodium Currents and Disrupted Firing Patterns in Purkinje Neurons of Scn8a Mutant Mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Solution structure of toxin 2 from centruroides noxius Hoffmann, a beta-scorpion neurotoxin acting on sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Amino acid sequence and immunological characterization with monoclonal antibodies of two toxins from the venom of the scorpion Centruroides noxius Hoffmann

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

SWISS-MODEL: An automated protein homology-modeling server

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

MOLMOL: a program for display and analysis of macromolecular structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Binding specificity of sea anemone toxins to Nav 1.1-1.6 sodium channels: unexpected contributions from differences in the IV/S3-S4 outer loop.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

ERG K+ channel blockade enhances firing and epinephrine secretion in rat chromaffin cells: the missing link to LQT2-related sudden death?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Resurgence of sodium channel research

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Molecular cloning, distribution and functional analysis of the NA(V)1.6. Voltage-gated sodium channel from human brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Electrophysiological properties of in vitro Purkinje cell somata in mammalian cerebellar slices

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

A-type potassium currents active at subthreshold potentials in mouse cerebellar Purkinje cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Inactivation and recovery of sodium currents in cerebellar Purkinje neurons: evidence for two mechanisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Na+ channels must deactivate to recover from inactivation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Compact myelin dictates the differential targeting of two sodium channel isoforms in the same axon.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Beta-scorpion toxin effects suggest electrostatic interactions in domain II of voltage-dependent sodium channels.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Endogenous expression of the beta1A sodium channel subunit in HEK-293 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Common features in the functional surface of scorpion beta-toxins and elements that confer specificity for insect and mammalian voltage-gated sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Fab fragments of the monoclonal antibody BCF2 are capable of neutralizing the whole soluble venom from the scorpion Centruroides noxius Hoffmann.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Primate models of movement disorders of basal ganglia origin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Subthalamic nucleus or internal pallidal stimulation in young onset Parkinson's disease

1 reference

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21 January 2018

Functional recovery in a primate model of Parkinson's disease following motor cortex stimulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Subthreshold sodium currents and pacemaking of subthalamic neurons: modulation by slow inactivation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

Sodium currents in subthalamic nucleus neurons from Nav1.6-null mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600565200

21 January 2018

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