(Q34437066)

2 August 2017

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title

Alpha-1-antitrypsin deficiency: a new paradigm for hepatocellular carcinoma in genetic liver disease (English)

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2 August 2017

main subject

hepatocellular carcinoma

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alpha-1-antitrypsin deficiency

inferred from title

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David A Rudnick

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2 August 2017

David H Perlmutter

series ordinal

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2 August 2017

language of work or name

English

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publication date

1 September 2005

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2 August 2017

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

514-521

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Mitochondrial autophagy and injury in the liver in alpha 1-antitrypsin deficiency.

2 August 2017

cites work

1 reference

Different types of ground glass hepatocytes in chronic hepatitis B virus infection contain specific pre-S mutants that may induce endoplasmic reticulum stress

21 January 2018

1 reference

Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency

21 January 2018

1 reference

7 January 2021

Neonatal hepatitis induced by alpha 1-antitrypsin: a transgenic mouse model

1 reference

7 January 2021

Accumulation of PiZ alpha 1-antitrypsin causes liver damage in transgenic mice

1 reference

7 January 2021

Analyses of hepatocellular proliferation in a mouse model of alpha-1-antitrypsin deficiency

1 reference

7 January 2021

Liver Disease in Alpha1-Antitrypsin Deficiency Detected by Screening of 200,000 Infants

1 reference

7 January 2021

The natural history of liver disease in alpha 1-antitrypsin deficient children

1 reference

7 January 2021

Alpha1-antitrypsin polymerization and the serpinopathies: pathobiology and prospects for therapy

1 reference

7 January 2021

The mechanism of Z alpha 1-antitrypsin accumulation in the liver

1 reference

7 January 2021

A thermostable mutation located at the hydrophobic core of alpha 1-antitrypsin suppresses the folding defect of the Z-type variant

1 reference

7 January 2021

Mutations which impede loop/sheet polymerization enhance the secretion of human alpha 1-antitrypsin deficiency variants

1 reference

7 January 2021

A naturally occurring nonpolymerogenic mutant of alpha 1-antitrypsin characterized by prolonged retention in the endoplasmic reticulum

1 reference

7 January 2021

A lag in intracellular degradation of mutant alpha 1-antitrypsin correlates with the liver disease phenotype in homozygous PiZZ alpha 1-antitrypsin deficiency

1 reference

7 January 2021

Proteasome-dependent endoplasmic reticulum-associated protein degradation: an unconventional route to a familiar fate

1 reference

7 January 2021

Degradation of a mutant secretory protein, alpha1-antitrypsin Z, in the endoplasmic reticulum requires proteasome activity

1 reference

7 January 2021

The proteasome participates in degradation of mutant alpha 1-antitrypsin Z in the endoplasmic reticulum of hepatoma-derived hepatocytes

1 reference

7 January 2021

Organizational diversity among distinct glycoprotein endoplasmic reticulum-associated degradation programs

1 reference

7 January 2021

Role of the proteasome in membrane extraction of a short-lived ER-transmembrane protein

1 reference

7 January 2021

Processing by endoplasmic reticulum mannosidases partitions a secretion-impaired glycoprotein into distinct disposal pathways

1 reference

7 January 2021

Signaling the unfolded protein response from the endoplasmic reticulum.

1 reference

7 January 2021

Translational control in the endoplasmic reticulum stress response

1 reference

7 January 2021

Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retention

1 reference

7 January 2021

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

1 reference

7 January 2021

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

1 reference

7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

7 January 2021

Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

1 reference

7 January 2021

A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum

1 reference

7 January 2021

Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol

1 reference

7 January 2021

Histopathology of α1-antitrypsin liver disease in a transgenic mouse model

1 reference

7 January 2021

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

1 reference

7 January 2021

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

1 reference

7 January 2021

Hsp27 negatively regulates cell death by interacting with cytochrome c.

1 reference

7 January 2021

Synthesis of stress proteins is increased in individuals with homozygous PiZZ alpha 1-antitrypsin deficiency and liver disease

1 reference

7 January 2021

Liver carcinoma in PiZ alpha-1-antitrypsin deficiency

1 reference

7 January 2021

Chronic liver disease in murine hereditary tyrosinemia type 1 induces resistance to cell death.

1 reference

7 January 2021

Self-induced correction of the genetic defect in tyrosinemia type I

1 reference

7 January 2021

Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I.

1 reference

7 January 2021

Frequent mutation reversion inversely correlates with clinical severity in a genetic liver disease, hereditary tyrosinemia

1 reference

7 January 2021

Expression of hepatitis B virus surface and core antigens: influences of pre-S and precore sequences

1 reference

7 January 2021

Identifiers

DOI

10.1002/HEP.20815

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2 August 2017

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