(Q34479743)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23157615%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

title

Expression of the platencin biosynthetic gene cluster in heterologous hosts yielding new platencin congeners (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23157615%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

main subject

Streptomyces lividans

1 reference

1 reference

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23157615%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Michael J Smanski

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23157615%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Jeffrey Casper

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23157615%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Zhiguo Yu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23157615%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Scott R Rajski

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23157615%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Ben Shen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23157615%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

publication date

16 November 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23157615%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

18 February 2020

https://europepmc.org/articles/pmc3532557?pdf=render

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1021/np3005985?email=unpaywall_01@example.com

published in

Journal of Natural Products

1 reference

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18 February 2020

volume

1 reference

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18 February 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23157615%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

page(s)

2158-2167

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23157615%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1021/np3005985?email=unpaywall_01@example.com

access restriction status

open access

1 reference

inferred from online access status

cites work

Expression of biosynthetic gene clusters in heterologous hosts for natural product production and combinatorial biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

A designer bleomycin with significantly improved DNA cleavage activity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Thoughts and facts about antibiotics: where we are now and where we are heading

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Natural products as sources of new drugs over the 30 years from 1981 to 2010

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Current approaches to exploit actinomycetes as a source of novel natural products.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Engineering of Streptomyces platensis MA7339 for overproduction of platencin and congeners.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Drug discovery and natural products: end of an era or an endless frontier?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Engineered Streptomyces platensis strains that overproduce antibiotics platensimycin and platencin.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Engineered production of iso-migrastatin in heterologous Streptomyces hosts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Feast or famine: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Regulation of secondary metabolism in streptomycetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Combinatorial biosynthesis of antitumor indolocarbazole compounds

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Assignment of the absolute configuration of alpha-chiral carboxylic acids by 1H NMR spectroscopy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027 apoprotein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Engineered biosynthesis of novel polyketides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

Terpenes with antimicrobial activity from Cretan propolis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3532557

GIBBERELLIN BIOSYNTHESIS: Enzymes, Genes and Their Regulation

27 October 2018

1 reference

12 December 2020

Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy

1 reference

12 December 2020

Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad-Spectrum Antibiotic Activity

1 reference

12 December 2020

Recombinant polyketide synthesis in Streptomyces: engineering of improved host strains

1 reference

12 December 2020

Identifiers

DOI

10.1021/NP3005985

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23157615%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23157615%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

PubMed publication ID

23157615

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23157615%20AND%20SRC:MED&resulttype=core&format=json