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Protein aggregation: folding aggregates, inclusion bodies and amyloid

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Europe PubMed Central

PubMed publication ID

2 August 2017

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Europe PubMed Central

Protein aggregation: folding aggregates, inclusion bodies and amyloid (English)

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Europe PubMed Central

PubMed publication ID

2 August 2017

protein folding

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protein aggregation

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author name string

Fink AL

1

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Europe PubMed Central

PubMed publication ID

2 August 2017

publication date

1 January 1998

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Folding & design

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

R9-23

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Europe PubMed Central

PubMed publication ID

2 August 2017

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Conformational disease

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Transient aggregates in protein folding are easily mistaken for folding intermediates

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Solubility as a function of protein structure and solvent components

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Mutations and off-pathway aggregation of proteins

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Folding and association versus misfolding and aggregation of proteins

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For protein misassembly, it's the "I" decade

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Evidence of an associative intermediate on the myoglobin refolding pathway

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The radius of gyration of an apomyoglobin folding intermediate

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Protein globularization during folding. A study by synchrotron small-angle X-ray scattering

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Defective protein folding as a basis of human disease

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Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

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Stability of ribonuclease A in solution and the freeze-dried state

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Infrared Spectroscopic Studies of Lyophilization‐ and Temperature‐Induced Protein Aggregation

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The secondary structure and aggregation of lyophilized tetanus toxoid

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Aggregation of rhDNase occurred during the compression of KBr pellets used for FTIR spectroscopy.

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The aggregation of bovine serum albumin in solution and in the solid state

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Optimization of lyophilization conditions for recombinant human interleukin-2 by dried-state conformational analysis using Fourier-transform infrared spectroscopy

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Dehydration-induced conformational transitions in proteins and their inhibition by stabilizers

1 reference

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Fourier-transform infrared spectroscopic investigation of protein stability in the lyophilized form

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Renaturation of Escherichia coli tryptophanase after exposure to 8 M urea. Evidence for the existence of nucleation centers

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Thermolabile folding intermediates: inclusion body precursors and chaperonin substrates.

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Multimeric intermediates in the pathway to the aggregated inclusion body state for P22 tailspike polypeptide chains

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A role for destabilizing amino acid replacements in light-chain amyloidosis

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Nativelike secondary structure in interleukin-1 beta inclusion bodies by attenuated total reflectance FTIR.

1 reference

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Folding pathway of human alpha 1-antitrypsin: characterization of an intermediate that is active but prone to aggregation

1 reference

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Compact Intermediate States in Protein Folding

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Domain swapping: entangling alliances between proteins

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Aggregation and denaturation of apomyoglobin in aqueous urea solutions

1 reference

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Serum amyloid P component prevents proteolysis of the amyloid fibrils of Alzheimer disease and systemic amyloidosis

1 reference

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7 January 2021

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Reversible self-association of bovine growth hormone during equilibrium unfolding

1 reference

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Folding of bovine growth hormone is consistent with the molten globule hypothesis

1 reference

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Evidence for a self-associating equilibrium intermediate during folding of human growth hormone

1 reference

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Protein compositional analysis of inclusion bodies produced in recombinant Escherichia coli

1 reference

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7 January 2021

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Folding of the phage P22 coat protein in vitro

1 reference

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Folding and aggregation of TEM beta-lactamase: analogies with the formation of inclusion bodies in Escherichia coli

1 reference

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Predicting the solubility of recombinant proteins in Escherichia coli

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Structure and morphology of protein inclusion bodies in Escherichia coli

1 reference

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Global suppression of protein folding defects and inclusion body formation

1 reference

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Amino acid substitutions influencing intracellular protein folding pathways

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Specific aggregation of partially folded polypeptide chains: the molecular basis of inclusion body composition

1 reference

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based on heuristic

inferred from DOI database lookup

Conformation of P22 tailspike folding and aggregation intermediates probed by monoclonal antibodies

1 reference

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Mutations in human interferon gamma affecting inclusion body formation identified by a general immunochemical screen

1 reference

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1 reference

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Evidence that the methylesterase of bacterial chemotaxis may be a serine hydrolase

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Inclusion body formation by interleukin-1 beta depends on the thermal sensitivity of a folding intermediate

1 reference

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7 January 2021

based on heuristic

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Breakdown in the relationship between thermal and thermodynamic stability in an interleukin-1 beta point mutant modified in a surface loop

1 reference

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1 reference

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based on heuristic

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Secondary structure characterization of beta-lactamase inclusion bodies.

1 reference

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based on heuristic

inferred from DOI database lookup

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1 reference

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inferred from DOI database lookup

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

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based on heuristic

inferred from DOI database lookup

Amyloid P component promotes aggregation of Alzheimer's beta-amyloid peptide

1 reference

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1 reference

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Partial denaturation of transthyretin is sufficient for amyloid fibril formation in vitro

1 reference

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based on heuristic

inferred from DOI database lookup

The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

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based on heuristic

inferred from DOI database lookup

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

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based on heuristic

inferred from DOI database lookup

Alternative conformations of amyloidogenic proteins govern their behavior

1 reference

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7 January 2021

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Specificity of abnormal assembly in immunoglobulin light chain deposition disease and amyloidosis

1 reference

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based on heuristic

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The C-terminus of the beta protein is critical in amyloidogenesis

1 reference

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based on heuristic

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1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

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based on heuristic

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1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Prion protein peptides induce alpha-helix to beta-sheet conformational transitions

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Scrapie amyloid (prion) protein has the conformational characteristics of an aggregated molten globule folding intermediate

1 reference

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1 reference

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7 January 2021

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Physical, morphological and functional differences between ph 5.8 and 7.4 aggregates of the Alzheimer's amyloid peptide Abeta

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Structural model for the β-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of beta-crystallite assemblies formed by Alzheimer beta-amyloid protein analogues: analysis by x-ray diffraction.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous β-sheet helix

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Examination of the Structure of the Transthyretin Amyloid Fibril by Image Reconstruction from Electron Micrographs

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Beta-helical fibrils from a model peptide

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Observation of metastable Abeta amyloid protofibrils by atomic force microscopy

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Creation of "Amyloid" Fibrils from Bence Jones Proteins in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The prion folding problem.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Support for the prion hypothesis for inheritance of a phenotypic trait in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural clues to prion replication

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Refolding and aggregation of bovine carbonic anhydrase B: quasi-elastic light scattering analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Transient association of the first intermediate during the refolding of bovine carbonic anhydrase B

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

A kinetic study of the competition between renaturation and aggregation during the refolding of denatured-reduced egg white lysozyme.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Refolding of denatured and denatured/reduced lysozyme at high concentrations

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Renaturation of lysozyme--temperature dependence of renaturation rate, renaturation yield, and aggregation: identification of hydrophobic folding intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Aggregation of chymotrypsinogen: portrait by infrared spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Discrete intermediates versus molten globule models for protein folding: characterization of partially folded intermediates of apomyoglobin

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The use of light-scattering and turbidity measurements to study the kinetics of extensively aggregating proteins: alphas-casein

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Light scattering analysis of fibril growth from the amino-terminal fragment beta(1-28) of beta-amyloid peptide

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Prionics or the kinetic basis of prion diseases

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Kinetics of aggregation of synthetic beta-amyloid peptide

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein aggregation in vitro and in vivo: a quantitative model of the kinetic competition between folding and aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Simulations of kinetically irreversible protein aggregate structure

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Kinetic theory of fibrillogenesis of amyloid β-protein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyloid fibril formation requires a chemically discriminating nucleation event: studies of an amyloidogenic sequence from the bacterial protein OsmB

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

A model for the denaturation and aggregation of beta-lactoglobulin.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Solvent effects on self-assembly of beta-amyloid peptide

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Radical changes in beta-amyloid form and function

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Reconstitution of lactic dehydrogenase. Noncovalent aggregation vs. reactivation. 1. Physical properties and kinetics of aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Reconstitution of lactic dehydrogenase. Noncovalent aggregation vs. reactivation. 2. Reactivation of irreversibly denatured aggregates

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Kinetics and mechanism of amyloid formation by the prion protein H1 peptide as determined by time-dependent ESR

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Classification of acid denaturation of proteins: intermediates and unfolded states

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the stable, acid-induced, molten globule-like state of staphylococcal nuclease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein anatomy: spontaneous formation of filamentous helical structures from the N-terminal module of barnase

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular chaperones in cellular protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

ATP-induced protein-Hsp70 complex dissociation requires K+ but not ATP hydrolysis.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of ATP in the functional cycle of the DnaK chaperone system

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Chaperone-assisted protein folding.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Chaperonin-mediated folding in the eukaryotic cytosol proceeds through rounds of release of native and nonnative forms

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

GroEL-mediated protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

A thermodynamic coupling mechanism for GroEL-mediated unfolding

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Protein folding in the cytoplasm of Escherichia coli: requirements for the DnaK-DnaJ-GrpE and GroEL-GroES molecular chaperone machines.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Refolding intermediates of acid-unfolded mitochondrial aspartate aminotransferase bind to hsp70

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

DnaK-mediated alterations in human growth hormone protein inclusion bodies

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Cooperation of GroEL/GroES and DnaK/DnaJ heat shock proteins in preventing protein misfolding in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Substrate shuttling between the DnaK and GroEL systems indicates a chaperone network promoting protein folding.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The ATP hydrolysis-dependent reaction cycle of the Escherichia coli Hsp70 system DnaK, DnaJ, and GrpE

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular chaperone functions of heat-shock proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein misfolding and inclusion body formation in recombinant Escherichia coli cells overexpressing Heat-shock proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

In vitro folding of inclusion body proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Improving protein refolding yields by minimizing aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Control of aggregation in protein refolding: a variety of surfactants promote renaturation of carbonic anhydrase II.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibiting transthyretin amyloid fibril formation via protein stabilization

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Routes to active proteins from transformed microorganisms

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein folding in vivo and renaturation of recombinant proteins from inclusion bodies

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular chaperones, folding catalysts, and the recovery of active recombinant proteins fromE. coli

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Improved refolding of an immobilized fusion protein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of correctly folded proteins in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Artificial chaperone-assisted refolding of denatured-reduced lysozyme: modulation of the competition between renaturation and aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The Hofmeister effect and the behaviour of water at interfaces

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Control of aggregation in protein refolding: the temperature-leap tactic

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

A strategy for designing inhibitors of beta-amyloid toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Anti-amyloid drugs: potential in the treatment of diseases associated with aging

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Seeding of A beta fibril formation is inhibited by all three isotypes of apolipoprotein E.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-0278%2898%2900002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S1359-0278(98)00002-9

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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