(Q34387499)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22911707%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Substrate stiffness and oxygen as regulators of stem cell differentiation during skeletal tissue regeneration: a mechanobiological model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22911707%20AND%20SRC:MED&resulttype=core&format=json

stem cell differentiation

11 February 2020

main subject

1 reference

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22911707%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Darren Paul Burke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22911707%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

language of work or name

English

0 references

publication date

24 July 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22911707%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22911707%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22911707%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22911707%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

page(s)

e40737

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22911707%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

11 February 2020

start time

24 July 2012

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

cites work

Dynamic compressive loading enhances cartilage matrix synthesis and distribution and suppresses hypertrophy in hMSC-laden hyaluronic acid hydrogels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Mechanical regulation of vascular growth and tissue regeneration in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

The metabolism of human mesenchymal stem cells during proliferation and differentiation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

The effect of matrix stiffness on the differentiation of mesenchymal stem cells in response to TGF-β

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Occurrence and treatment of bone atrophic non-unions investigated by an integrative approach

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Hypoxia and stem cell-based engineering of mesenchymal tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Assessment of a mechano-regulation theory of skeletal tissue differentiation in an in vivo model of mechanically induced cartilage formation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Thrombospondin-2 influences the proportion of cartilage and bone during fracture healing.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Angiogenesis in bone fracture healing: a bioregulatory model.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Angiogenesis modulates adipogenesis and obesity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Endochondral ossification: how cartilage is converted into bone in the developing skeleton.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Stem cells and adipose tissue engineering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Matrix elasticity directs stem cell lineage specification

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Mechano-regulation of stem cell differentiation and tissue regeneration in osteochondral defects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Adipose tissue angiogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Developmental regulation of the growth plate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Finite element models in tissue mechanics and orthopaedic implant design

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Stiffness of compact bone: effects of porosity and density

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Skeletal structural adaptations to mechanical usage (SATMU): 1. Redefining Wolff's law: the bone modeling problem

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

ESB Research Award 1996. Biophysical stimuli on cells during tissue differentiation at implant interfaces

6 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Comparison of biophysical stimuli for mechano-regulation of tissue differentiation during fracture healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

A mechano-regulation model for tissue differentiation during fracture healing: analysis of gap size and loading

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Prediction of the optimal mechanical properties for a scaffold used in osteochondral defect repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Bone regeneration during distraction osteogenesis: mechano-regulation by shear strain and fluid velocity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Tissue differentiation and bone regeneration in an osteotomized mandible: a computational analysis of the latency period

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

The influence of expansion rates on mandibular distraction osteogenesis: a computational analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Corroboration of mechanobiological simulations of tissue differentiation in an in vivo bone chamber using a lattice-modeling approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Differential effects of hypoxia on osteochondrogenic potential of human adipose-derived stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

A mechanobiological model for tissue differentiation that includes angiogenesis: a lattice-based modeling approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Simulation of the nutrient supply in fracture healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Mechanical loading affects angiogenesis and osteogenesis in an in vivo bone chamber: a modeling study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

A hybrid bioregulatory model of angiogenesis during bone fracture healing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Hypoxia promotes chondrogenesis in rat mesenchymal stem cells: a role for AKT and hypoxia-inducible factor (HIF)-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Oxygen tension differentially regulates the functional properties of cartilaginous tissues engineered from infrapatellar fat pad derived MSCs and articular chondrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Osteogenic differentiation of hypertrophic chondrocytes involves asymmetric cell divisions and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

A numerical model of the fracture healing process that describes tissue development and revascularisation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Impact of oxygen environment on mesenchymal stem cell expansion and chondrogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Pressure, oxygen tension and temperature in the periosteal callus during bone healing--an in vivo study in sheep.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Biomechanical model to simulate tissue differentiation and bone regeneration: application to fracture healing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Simulation of fracture healing in the tibia: Mechanoregulation of cell activity using a lattice modeling approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Oxygen tension regulates the osteogenic, chondrogenic and endochondral phenotype of bone marrow derived mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Antiangiogenic treatment delays chondrocyte maturation and bone formation during limb skeletogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Initial vascularization and tissue differentiation are influenced by fixation stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Influence of fracture gap size on the pattern of long bone healing: a computational study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

Computational simulation of fracture healing: influence of interfragmentary movement on the callus growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040737

The spatio-temporal arrangement of different tissues during bone healing as a result of simple mechanobiological rules

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404068

Low oxygen tension is a more potent promoter of chondrogenic differentiation than dynamic compression

27 October 2018

1 reference

12 December 2020

Mechanobiology of skeletal regeneration

1 reference

12 December 2020

A Mathematical Framework to Study the Effects of Growth Factor Influences on Fracture Healing

1 reference

12 December 2020

Temporal tissue patterns in bone healing of sheep

1 reference

12 December 2020

The vascular repair of an experimental osteotomy held in an external fixator

1 reference

12 December 2020

Temporal and spatial vascularization patterns of unions and nonunions: role of vascular endothelial growth factor and bone morphogenetic proteins

1 reference

12 December 2020

Mechanical properties of the fibrous tissue found at the bone-cement interface following total joint replacement

1 reference

12 December 2020

Correlations between mechanical stress history and tissue differentiation in initial fracture healing

1 reference

12 December 2020

A mechano-regulation model of fracture repair in vertebral bodies

1 reference

12 December 2020

Mechano-regulation of mesenchymal stem cell differentiation and collagen organisation during skeletal tissue repair

1 reference

12 December 2020

Elastic modulus of calcified cartilage is an order of magnitude less than that of subchondral bone

1 reference

12 December 2020

Prevention of fracture healing in rats by an inhibitor of angiogenesis

1 reference

12 December 2020

The effect of mechanical stability on local vascularization and tissue differentiation in callus healing

1 reference

12 December 2020

The effect of matrix stiffness on mesenchymal stem cell differentiation in a 3D thixotropic gel

1 reference

12 December 2020

Cell-matrix interactions regulate mesenchymal stem cell response to hydrostatic pressure

1 reference

12 December 2020

Magnitudes of local stress and strain along bony surfaces predict the course and type of fracture healing

1 reference

12 December 2020

Regulation of bone mass by mechanical strain magnitude

1 reference

12 December 2020

Variations in the intrinsic mechanical properties of human articular cartilage with age, degeneration, and water content

1 reference

12 December 2020

A new theory on the influence of mechanical stimuli on the differentiation of supporting tissue. The tenth contribution to the functional anatomy and causal morphology of the supporting structure

1 reference

12 December 2020

Reduced oxygen tension attenuates differentiation capacity of human mesenchymal stem cells and prolongs their lifespan

1 reference

12 December 2020

Hydrostatic pressure acts to stabilise a chondrogenic phenotype in porcine joint tissue derived stem cells

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0040737

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22911707%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22911707%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

22911707

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22911707%20AND%20SRC:MED&resulttype=core&format=json