(Q34369829)

1 August 2017

title

"Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally (English)

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1 August 2017

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Manuel Serrano

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María A Blasco

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Isabel García-Cao

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1 August 2017

Marta García-Cao

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1 August 2017

Juan Martín-Caballero

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1 August 2017

Luis M Criado

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1 August 2017

Peter Klatt

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1 August 2017

Juana M Flores

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1 August 2017

Jean-Claude Weill

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1 August 2017

language of work or name

English

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publication date

1 November 2002

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1 August 2017

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

6225-6235

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p53 mutant mice that display early ageing-associated phenotypes

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Putting the stress on senescence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Human germline gene therapy reconsidered

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Size matters: use of YACs, BACs and PACs in transgenic animals

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Regulation of p53 function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Transgenic monkeys produced by retroviral gene transfer into mature oocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

6 July 2018

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Cellular senescence: mitotic clock or culture shock?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

6 July 2018

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Mitotic recombination produces the majority of recessive fibroblast variants in heterozygous mice.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

The INK4A/ARF locus and its two gene products

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

High susceptibility of p53(+/-) knockout mice in N-butyl-N-(4-hydroxybutyl)nitrosamine urinary bladder carcinogenesis and lack of frequent mutation in residual allele.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Loss of p 21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm -deficient mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

p53 is required for radiation-induced apoptosis in mouse thymocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Tumor spectrum analysis in p53-mutant mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Radiation-induced cell cycle arrest compromised by p21 deficiency

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Pulmonary metastases from autochthonous 3-methylcholanthrene-induced murine tumors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137187

Genetic technologies. Facing inheritable genetic modifications.

6 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDF595

21 January 2018

Biology's last taboo.

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDF595

Tumor surveillance via the ARF-p53 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDF595

p19ARF links the tumour suppressor p53 to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDF595

In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice

21 January 2018

1 reference

12 December 2020

Enhanced proliferative potential in culture of cells from p53-deficient mice

1 reference

12 December 2020

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

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12 December 2020

Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys

1 reference

12 December 2020

Testicular wild-type p53 expression in transgenic mice induces spermiogenesis alterations ranging from differentiation defects to apoptosis

1 reference

12 December 2020

Clonal analysis of urothelial carcinomas in C3H/HeN<-->BALB/c chimeric mice treated with N-butyl-N-(4-hydroxybutyl)nitrosamine

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/CDF595

1 reference

1 August 2017

1 reference

1 August 2017

1 reference