(Q34351574)

1 August 2017

title

Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons (English)

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1 August 2017

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Bruce J Brew

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1 August 2017

Gilles J Guillemin

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1 August 2017

George Smythe

series ordinal

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1 August 2017

Osamu Takikawa

series ordinal

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1 August 2017

language of work or name

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1 January 2005

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1 August 2017

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

15-23

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Human microglia convert l-tryptophan into the neurotoxin quinolinic acid

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20090

Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types

21 January 2018

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The preferred route of kynurenine metabolism in the rat

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7 January 2021

Regulation of indoleamine 2,3-dioxygenase expression in simian immunodeficiency virus-infected monkey brains

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7 January 2021

Distribution of quinolinic acid phosphoribosyltransferase in the human hippocampal formation and parahippocampal gyrus

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https://api.crossref.org/works/10.1002%2FGLIA.20090

7 January 2021

Immunohistochemical localization of quinolinic acid phosphoribosyltransferase in the human neostriatum

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https://api.crossref.org/works/10.1002%2FGLIA.20090

7 January 2021

Activated human microglia produce the excitotoxin quinolinic acid

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7 January 2021

Species differences in L-tryptophan-kynurenine pathway metabolism: quantification of anthranilic acid and its related enzymes

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7 January 2021

Characterization of ameboid microglia isolated from developing mammalian brain.

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7 January 2021

Tolerance, DCs and tryptophan: much ado about IDO

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7 January 2021

Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease

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7 January 2021

Obtention and characterization of primary astrocyte and microglial cultures from adult monkey brains

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https://api.crossref.org/works/10.1002%2FGLIA.20090

7 January 2021

Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection

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https://api.crossref.org/works/10.1002%2FGLIA.20090

7 January 2021

A beta 1-42 induces production of quinolinic acid by human macrophages and microglia

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7 January 2021

Tissue distribution of indoleamine 2,3-dioxygenase in normal and malaria-infected tissue

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7 January 2021

Chronic exposure of human neurons to quinolinic acid results in neuronal changes consistent with AIDS dementia complex

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7 January 2021

Quinolinic acid phosphoribosyltransferase: preferential glial localization in the rat brain visualized by immunocytochemistry

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7 January 2021

Quinolinic acid metabolism in the rat brain. Immunohistochemical identification of 3-hydroxyanthranilic acid oxygenase and quinolinic acid phosphoribosyltransferase in the hippocampal region

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7 January 2021

Immunohistochemical identification of quinolinic acid phosphoribosyltransferase in glial cultures from rat brain

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7 January 2021

Excitatory effects of kynurenine and its metabolites, amino acids and convulsants administered into brain ventricles: differences between rats and mice

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7 January 2021

Central nervous system activation of the indoleamine-2,3-dioxygenase pathway in human T cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis

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7 January 2021

Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy.

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7 January 2021

Tryptophan and the immune response

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7 January 2021

Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites

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7 January 2021

Prevention of allogeneic fetal rejection by tryptophan catabolism

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7 January 2021

Abnormally high activity of 3-hydroxyanthranilate 3,4-dioxygenase in brain of epilepsy-prone El mice

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7 January 2021

Quinolinic acid phosphoribosyltransferase: purification and partial characterization from human liver and brain

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7 January 2021

Quinolinic acid production by macrophages stimulated with IFN-gamma, TNF-alpha, and IFN-alpha.

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https://api.crossref.org/works/10.1002%2FGLIA.20090

7 January 2021

Frontal cortex indoleamine-2,3-dioxygenase activity is increased in HIV-1-associated dementia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20090

7 January 2021

Potential role of human brain microvascular endothelial cells in the pathogenesis of brain abscess: inhibition of Staphylococcus aureus by activation of indoleamine 2,3-dioxygenase

1 reference

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7 January 2021

Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain

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https://api.crossref.org/works/10.1002%2FGLIA.20090

7 January 2021

Quinolinic acid is produced by macrophages stimulated by platelet activating factor, Nef and Tat.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20090

7 January 2021

Concurrent quantification of quinolinic, picolinic, and nicotinic acids using electron-capture negative-ion gas chromatography-mass spectrometry

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20090

7 January 2021

Endogenous neurotoxins from tryptophan

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https://api.crossref.org/works/10.1002%2FGLIA.20090

7 January 2021

Endogenous kynurenines as targets for drug discovery and development

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20090

7 January 2021

Quinolinic acid: a potent endogenous excitant at amino acid receptors in CNS

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20090

7 January 2021

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20090

7 January 2021

Characteristics of interferon induced tryptophan metabolism in human cells in vitro

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20090

7 January 2021

Identifiers

DOI

10.1002/GLIA.20090

1 reference

1 August 2017

1 reference